Hepatocyte specific contrast agents including gadoxetic acid and gadobenate dimeglumine are very useful to diagnose various benign and malignant focal hepatic lesions and even helpful to estimate hepatic functional reservoir. The far delayed phase image referred to as the hepatobiliary phase makes the sensitivity of detection for malignant focal hepatic lesions increased, but specificity of malignant diseases, including hepatocellular carcinoma, metastasis and cholangiocarcinoma, characterization remained to be undetermined.
Carcinoma, Hepatocellular/radiography ; Cholangiocarcinoma/radiography ; Contrast Media/chemistry/*diagnostic use ; Hemangioma/radiography ; Humans ; Liver Diseases/*radiography ; Liver Neoplasms/radiography ; Magnetic Resonance Imaging ; Meglumine/*analogs & derivatives/chemistry/diagnostic use ; Organometallic Compounds/chemistry/*diagnostic use