OBJECTIVETo investigate the chemical constituents from Hedyotis diffusa.

METHODThe compounds were isolated and purified by various chromatographic techniques and identified by their physicochemical properties and spectral data.

RESULTEight compounds had been reported in last paper, and this time eight more compounds were isolated and identified as 6-hydroxystigmasta-4,22-dien-3-one (1), 3-hydroxystigmasta-4,22-dien-7-one (2), 2-hydroxy-3-methylanthraquinone (3), 2,6-dihydroxy-3-methyl-4-methoxyanthraquinone (4), iso-scutellarein (5), isoetin (6), aesculetin (7), gypsogenic acid (8).

CONCLUSIONCompounds 1-3, 5-8 were obtained from the genus Hedyotis for the first time.

OBJECTIVETo study the chemical constituents of Usnea longissima.

METHODThe compounds were isolated and purified by the methods of solvent extraction and chromatographic technique, and their structures were identified on the basis of the analysis of spectral data or comparison with those of authentic sample.

RESULTThirteen compounds were obtained and identified as ethyl hematommate (1), friedelin (2), beta-amyrin (3), beta-sitosterol (4), methyl-2,4-dihydroxy-3,6-dimethylbenzoate (5), barbatinic acid (6), zeorin (7), ethyl orsellinate (8), 3beta-hydroxy-glutin-5-ene (9), oleanolic acid (10), (+)-usnic acid (11), methylorsellinate (12), and 4-methyl-2,6-dihydroxy-benzaldehyde (13).

CONCLUSIONCompounds 2, 3, 5, and 8-10 were isolated from this genus for the first time, and compounds 1,4 were obtained from this plant for the first time.

Thirteen compounds were isolated from the leaves of Rhododendron rubiginosum var. rubiginosum by various chromatographic techniques. On the basis of spectroscopic data, their structures were elucidated as 3,9-dihydroxy-megastigma-5-ene (1), 3 beta-hydroxy-5alpha ,6 alpha-epoxy-7-megastigmen-9-one (2), loliolide (3), ursolic acid(4), 2 alpha, 3 beta-dihydroxy-urs-12-en-28-oic acid (5), 2 alpha, 3 beta,23-trihydroxy-urs-12-en-28-oic acid (6), 7,9-dimethoxyrhododendrol (7), 7-methoxyrhododendrol (8), zingerone (9), isofraxidin (10), scopoletin (11), (+)-pinoresinol (12) and 3'-O-demethylepipinorisenol (13). All compounds were isolated from this plant for the first time, and compounds 1-3, 7-9, and 11-13 were isolated from the genus Rhododendron for the first time.
Organic Chemicals ; analysis ; chemistry ; Plant Leaves ; chemistry ; Rhododendron ; chemistry

OBJECTIVETo study the chemical constituents from the roots of Linum usitatissimum.

METHODThe compounds were isolated and purified by silica gel column chromatography, their structures were elucidated by physico-chemical properties and spectroscopic data.

RESULTTen compounds were isolated and identified as vanillic acid (1), syringic acid (2), xanthine (3), vitexin (4), isovanillin (5), (E)-3,3'-dimethoxy-4,4'-dihydroxystilbene (6), tachioside (7), beta-sitosterol and stigmasterol (8 and 9) mixture, berberine (10).

CONCLUSIONCompounds 1-3, 5-7, 10 were isolated from L. usitatissimum for the first time.

OBJECTIVETo isolate and elucidate the chemical constituents of the fruits of Acanthopanax sessiliflorus.

METHODIsolation and purification were carried out on the column chromatography of silica gel and Sephadex LH-20. Their structures were elucidated on basis of physicochemical properties and spectral data.

RESULTNine compounds were isolated and identified as oleanolic acid-3-O-6'-O-methyl-beta-D-glucuronopyranoside (1), 22-alpha-hydroxychiisanogenin (2), oleanolic acid-3-O-beta-D-glucuronopyranoside (3), oleanolic acid-3-O-beta-D-glucopyranoside (4), oleanolic acid (5), chiisanogenin (6), (-)-sesamin (7), daucosterol (8), beta-sitosterol (9).

CONCLUSIONCompound 1 is obtained from the genus Acanthopanax genus for the first time. Compounds 2-5 are isolated from this plant for the first time.

OBJECTIVETo study the chemical constituents of Excoecaria acerifclia.

METHODColumn chromatography on Silica gel and Sephadex LH-20 were applied for isolation and purification of the constituents. The structures were elucidated on the basis of spectrascopic analysis, chemical evidences and by comparison with the data reported in the literature.

RESULTFrom the crude EtOAc fraction of Excoecaria acerifclia F. Didr, 14 compounds were isolated and identified as 7,8-trans-4,5,9-trihydroxy-3,3',9'-trimethoxy-7-O-5',8-O-4'-neolignan (1), 7,8-trans 4,5,9,9'-tetrahydroxy-3,3'-dimethoxy-7-O-5',8-O-4'-neolignan (2), malloapelin C (3), sy-ringaresinol (4), 2alpha,3beta,24-trihydroxy-12-ursen-28-oic acid (5), 11-hydroxy-3-oxo-12-ursen-28-oic acid (6), 6-hydroxy-20 (29)-lupen-3-one (7), isolupenyl acetate (8), kaempferol (9), quercetin (10), apigenin (11), catechin (12), kamepferol-3-O-beta-D-galactopyranoside (13), and catechin (6-->8) catechin (14).

CONCLUSIONSCompound 1 was new, the remained compounds were isolated and identified from E. acerifclia for the first time. Among them, compounds 5-8 are triterpenoids, while the other compounds are phenylpropanoids.

Chemical constituents of a new species of Spongia sponge collected from Sanya bay in Hainan province, were analyzed. Nine secondary metabolites 1-9 were isolated. On the basis of their spectroscopic data and chemical degradation, their chemical structures were determined as palmitoyl-heptacosane-1, 3, 5-triol (1), stigmast-4-en-3beta, 6beta-diol (2),2,3-dihydroxypropanyl hentetracosanate (3), sitosterol (4), thymine (5), gorgosterol (6), batyl alcohol (7), uracil (8) and thymidine (9). Palmitoyl-heptacosane-1, 3, 5-triol (1) is a new compound.
Animals ; Magnetic Resonance Spectroscopy ; Organic Chemicals ; analysis ; chemistry ; Porifera ; chemistry

OBJECTIVETo study the chemical constituents from the fruits of Ligustrum lucidum.

METHODThe chemical constituents from the ethanol extract of L. lucidum were isolated and purified by silica gel, Sephadex LH-20, ODS column chromatographic methods. Their structures were identified on the basis of spectroscopic data and physico-chemical properties.

RESULTTwenty compounds were isolated and identified as oleanolic acid (1), crategolic acid (2), acetyl oleanolic acid (3), lupeol (4), betulin (5), dammarenediol-II (6), 3beta-acetyl-20, 25-epoxydammarane-24alpha-ol (7), 25-epoxydammarane-3beta, 24alpha-diol (8), dammar-24-ene-3beta-acetyl-20S-ol) (9), 20S, 24R-dammarane-25-ene-24-hydroperoxy-3beta, 20-diol (10), fouquierol (11), oliganthas A (12), dammarenediol II 3-O-palmitate (13), ocotillol II 3-O-palmitate (14), (E) -25-hydroperoxydammar-23-ene-3beta,20-diol (15), verbascoside (16), cimidahurinine (17), 2-(3,4-dihydroxyphenyl)-ethyl-O-beta-D-glucopyranoside (18), osmanthuside H (19), 2-(3,4-dihydroxyphenyl) ethanol (20).

CONCLUSIONCompounds 4, 16,17, 19 were isolated from this plant for the first time, andcompounds 12-15 were isolated from this genus for the first time.

OBJECTIVETo study the chemical constituents of Sorbus tianschanica.

METHODThe compounds were isolated and purified by recrystallization and chromatography with silica gel and resin. Their structures were identified by physicochemical properties and spectral analysis.

RESULTSeven compounds were isolated from the EtOH extraction and six structures were identified as benzoic acid (1), benzyl-O-beta-D-glucopyranoside (2), ursolic acid (3), 2alpha-hydroxyursolic acid (4), hyperoside (5), quercetin-3-O-glucoside (6).

CONCLUSIONCompounds 1-5 were isolated from S. tianschanica for the first time.

The chemical constituents of Poria cocos were studied by means of silica gel, ODS column chromatography, Sephadex LH-20 and preparative HPLC. Thirteen compounds were isolated from this plant. By analysis of the ESI-MS and NMR data, the structures of these compounds were determined as tumulosic acid (1), dehydrotumulosic acid (2), 3beta, 5alpha-dihydroxy-ergosta-7, 22-dien-6-one (3), 3beta, 5alpha, 9alpha-trihydroxy-ergosta-7, 22-diene -6-one (4), ergosta-7, 22-diene-3-one (5), 6, 9-epoxy-ergosta-7,22-diene-3-ol (6), ergosta-4,22-diene-3-one (7), 3beta, 5alpha, 6beta-trihydroxyl-ergosta-7,22-diene (8), ergosta-5, 6-epoxy-7,22-dien-3-ol (9), beta-sitosterol (10), ribitol (11), mannitol (12), and oleanic acid 3-O-acetate (13), respectively. Compounds 3-13 were isolated from the P. cocos for the first time.
Drugs, Chinese Herbal ; chemistry ; Organic Chemicals ; analysis ; Poria ; chemistry