Based on the results of 20 cases with mumps orchitis who were treated with Prednisolon (25-30 mgs per day in 5 days) or Triamcinolon (5-6 mgs per day in 5 days), the author showed that corticoids could either release fever and pain within 24 hours or 48 hours, or reduce the swelling of orches faster in comparison with the other group of patients. Nevertheless, corticoids could not prevent the orches shrinking
Orchitis ; Mumps ; Therapeutics ; Adrenal Cortex Hormones

Cysts ; Epididymitis ; Humans ; Male ; Orchitis ; Urinary Tract Infections

Cryptococcus is native to the environment and thrives in any type of environment inhabited by birds. Cryptococcal genito-urinary infection has been reported in immunnocompromised patients and can involve the adrenal gland, kidney, prostate, or penis. To our knowledge, there have been no reports of cases where cryptococcal epididymo-orchitis infects an uncompromised healthy host. Here, we report a case of primary cryptococcal epididymo-orchitis in a healthy male.
Adrenal Glands ; Birds ; Cryptococcus ; Humans ; Kidney ; Male ; Orchitis ; Penis ; Prostate

The review summarized the recent progress on macrophages of male reproductive tract and the action of macrophages on male reproductive physiology and pathology. The close correlation and effect between testicular macrophages and Leydig cells, Sertoli cells, germ cells, hypothalamic-pituitary-gonadal axis were introduced, respectively. At the same time, it pointed out the changes of macrophages' morphology and function in immune orchitis, and their regulation on the development of orchitis. So the complex immune regulation network in testes and testicular macrophages playing an important role on spermatogenesis and the stableness of spermatogenetic microenvironment in testes were further illuminated, which can provide theoretical basis for clinic therapy.
Genitalia, Male ; cytology ; immunology ; physiology ; Humans ; Macrophages ; cytology ; immunology ; Male ; Orchitis ; immunology ; pathology ; Spermatogenesis ; physiology

OBJECTIVETo investigate the epidemiological characteristics, clinical manifestations, diagnosis, and treatment of Brucella orchitis, so as to provide reliable evidence for the prevention and treatment of the disease.

METHODSWe conducted retrospective statistical analyses on the medical records of 48 outpatients and 21 inpatients with Brucella orchitis.

RESULTSBrucella orchitis was diagnosed in 6.67% of the male patients with brucellosis (69/1 034). The disease exhibited typical epidemiological features, with a higher incidence rate among those in frequent contact with sheep and elderly people, in the period from April to July, and in the areas with sheep husbandry. All the Brucella orchitis patients had such local symptoms as testicular pain and swelling, more frequently involving both testes, and other most common symptoms included fever, chills, sweating, and painful joints. Based on IIEF-5, 45 of the patients suffered from severe erectile dysfunction, with their reproductive function temporarily affected in the course of the disease. Misdiagnosis easily occurred in the early stage of the disease. Therapeutic options mainly included doxycycline hydrochloride and rifampicin, administered orally or intravenously, which could effect a cure, though relapse might occur in some cases.

CONCLUSIONBru- cella orchitis has distinct epidemiological characteristics, with clinical manifestations of testicular pain and swelling. Though a transient disease, it affects the reproductive function of the patient before cured. It can be treated by combined oral and intravenous medication, with painkillers or ice bags for testicular pain and swelling.

Animals ; Brucella ; pathogenicity ; Brucellosis ; complications ; diagnosis ; therapy ; Humans ; Male ; Orchitis ; diagnosis ; microbiology ; therapy ; Retrospective Studies ; Sheep

Color Doppler ultrasonography was performed in 41 patients with the acute onset of scrotal pain. of the 32 cases of 33 inflammatory diseases (epididymitis n=19, epididymo-orchitis n=12, orchitis n=1) color Doppler image demonstrated increased epididymal or testicular flow. Color Doppler ultrasonography correctly predicted the need for surgery in 5 of 9 operated patients and correctly predicted the outcome in all 32 nonoperated patients. In the two cases of 3 detorsions which were evident in color Doppler ultrasonography was incorrectly diagnosed with testis scintigraphy. Color Doppler ultrasonography is more effective than testis scintigraphy. Results show that color Doppler ultrasonography helps accurately correlate anatomy and perfusion in real time and may prove to be the definitive imaging technique for the diagnostic evaluation of the acute scrotum.
Humans ; Male ; Orchitis ; Perfusion ; Radionuclide Imaging ; Scrotum* ; Testis ; Ultrasonography, Doppler, Color*

Behcet's disease is a multisystem disorder presented with recurrent oral and genital ulcerations as well as ocular involvement. The principal manifestations in the urinary system are glomerulonephritis, cystitis, epididymitis, orchitis, and genital ulcerations. Urethrovaginal fistula is an unusual complication. The primary lesion of the disease is a small vessel vasculitis with endothelial deposition of immunocomplexes, and consequent inflammatory and necrotizing process of the vascular wall. We experienced a 19-year-old woman with Behcet's disease, who had a large urethrovaginal fistula on the anterior vaginal wall. The size of fistula was 2x1cm. For this patient, we tried combining bulbocavernosus muscle and labial fat pad flap (Martius flap) urethral reconstruction. This operative method seemed to be safe and effective for the urethral defect with Behcet's disease.
Adipose Tissue ; Behcet Syndrome ; Cystitis ; Epididymitis ; Female ; Fistula* ; Glomerulonephritis ; Humans ; Male ; Orchitis ; Ulcer ; Vasculitis ; Young Adult

Brucellosis is a zoonosis, which is caused by Brucella abortus, B. melitensis, B. suis and B. canis. Brucellosis has been an emerging disease since the discovery of B. melitensis, by Bruce, in 1887. Worldwide, brucellosis remains a major source of disease in both humans and domesticated animals. A high prevalence in certain geographical areas is well recognized, but has been largely underestimated. In Korea, the first human case of Brucellosis occurred in 2002, but the incidence of human brucellosis has now increased. Herein, a case of epididymorchitis due to brucellosis is reported.
Animals, Domestic ; Brucella abortus ; Brucella* ; Brucellosis ; Epididymitis ; Humans ; Incidence ; Korea ; Male ; Orchitis ; Prevalence

PURPOSE: Mumps orchitis rarely occurs in prepubescent boys, but it is common in adolescents and adults. Approximately 30-40% of the affected testes are said to atrophy within several months as a complication, but any study on this is lacking. We studied the clinical outcomes and the ultrasonographic findings of mumps orchitis. MATERIALS AND METHODS: We studied 15 patients who had been hospitalized and followed up for more than 3 months from July 2003 to June 2005. The average age of the patients was 16 years old. The patients' medical history, therapeutic measures and clinical outcomes were recorded, and scrotal color doppler ultrasonography was performed at the follow up sessions after the treatment. The criteria for testicular atrophy have been set according to the contralateral testicular volume reduction of 20% or 2ml. RESULTS: During an average of 10 months of follow up period, 9 of 15 patients experienced atrophy and the contraction rate of the affected testes was about 39.8%. Two of 5 patients who under systemic interferon-alpha2b treatments experienced atrophy and their contraction rate was about 46.5%. On the ultrasonography, inhomogeneous and decreased echogenicity was noted in the atrophic testes and the blood flow comparably decreased. CONCLUSIONS: From the study, it has been confirmed that the interfereon-alpha2b treatment was not adequate to completely prevent the atrophy. Scrotal ultrasonography is a useful examination that is able to measure the correct testicular volume and judge testicular atrophy. As mumps orchitis seem to induce testicular atrophy, periodic check up may be required after the acute stage.
Adolescent ; Adult ; Atrophy ; Follow-Up Studies ; Humans ; Male ; Mumps* ; Orchitis* ; Testis ; Ultrasonography ; Ultrasonography, Doppler, Color

PURPOSE: Recently, we have noticed an increase in the number of patients with mumps in Incheon, Korea. The aim of this study is to estimate the regional trend in mumps incidence and to evaluate the factors related to the recent increase. METHODS: We reviewed the medical records of 66 patients with mumps who had been admitted to Incheon St. Mary's Hospital from July 1999 to June 2009. We compared the differences in records between "outbreak, 2009" and "nonoutbreak, 2000-2008." RESULTS: Of the 66 patients, 35 (53%) were admitted in 2009, and 31 (47%) were admitted between 2000 and 2008. Most of the patients admitted during the outbreak were over 15 years of age (80.0%), were born before 1993 (77.1%), and had received a single dose of mumps vaccine (62.9%). There were no significant differences in contact history, present address, clinical manifestations, and complications, except for orchitis, between the two groups. CONCLUSION: There was a sharp increase in the number of inpatients with mumps who were born before 1993 and who were over 15 years of age. We recommend that a booster vaccination be considered for adolescents and young adults born before 1993 who are susceptible to mumps infection due to their reduced opportunities for receiving two doses of mumps vaccine.
Adolescent ; Humans ; Incidence ; Inpatients ; Korea ; Male ; Medical Records ; Mumps ; Mumps Vaccine ; Orchitis ; Vaccination ; Young Adult