No abstract available.
CD4 Lymphocyte Count* ; Humans ; Oral Manifestations*

oral manifestations of the disease are posterior palate hemorrhage, gingival bleeding and gingival ulceration as a result of infection by normal oral flora and gingival infiltration by leukemic cells. A 49-year-old male patient was referred from local dental clinic. The patient was diagnosed with AML FAB M1 (acute myeloid leukemia French-American-British classification M1 myeloblastic leukemia without maturation). The oral infection focus was removed by a conservative treatment. 2 days after the dental treatment, the patient underwent chemotherapy. At 8-month follow-up, the overall outcome was excellent. Oral manifestations of AML are often the first indications of the malignancy. Therefore it is essential for dentists, especially oral and maxillofacial surgeons, to be aware of the diagnostic signs and complications associated with leukemia for better diagnosis and subsequent treatment and management.]]>
Cell Death ; Dental Clinics ; Dentists ; Follow-Up Studies ; Gingival Hemorrhage ; Granulocyte Precursor Cells ; Hemorrhage ; Humans ; Leukemia ; Leukemia, Myeloid ; Leukemia, Myeloid, Acute ; Male ; Middle Aged ; Oral Manifestations ; Palate ; Ulcer

Leukemia is a hematological malignant disease with various clinical symptoms. Due to the fatal nature of the disease, early detection is important. Oral manifestations include ulcers and gingival enlargement with bleeding. Moreover, myeloid sarcoma or opportunistic infections may also occur. This report introduces a 31-year-old male presenting with generalized gingival enlargement with bleeding and another 81-year-old female with neoplasm on the left retromolar area. Both were diagnosed as acute monocytic leukemia. These cases implicate that gingival enlargement or mucosal lesion in the oral cavity may represent underlying systemic diseases. Related to this, it has to be reminded that making timely diagnosis and referral according to the clinical findings is crucial.
Adult ; Aged, 80 and over ; Diagnosis ; Female ; Hemorrhage ; Humans ; Leukemia ; Leukemia, Monocytic, Acute ; Male ; Mouth ; Opportunistic Infections ; Oral Manifestations ; Referral and Consultation ; Sarcoma, Myeloid ; Ulcer

Non-Hodgkin's lymphoma is a heterogenous group of neoplasm affecting the lymphoid system. About 10% of Non-Hodgkin's lymphoma occur in the extra-nodal region in the head and neck area and more than half of extra-nodal lymphoma in the head and neck area involves the Waldeyer's ring. Localization in the oral cavity is rare. We experienced one rare case of Non-Hodgkin's lymphoma in the oral cavity, with trismus and persistent ulcerated swelling in the right-side cheek as the chief complaint.
Cheek ; Head ; Lymphoma ; Lymphoma, Non-Hodgkin* ; Mouth* ; Neck ; Oral Manifestations ; Trismus ; Ulcer

Osteonecrosis of the jaw (ONJ) is a well-known pathological condition in oncology derived from the use of bisphosphonates (BPs) and denosumab. Many molecular and immunological targets have been introduced for daily use in cancer treatment in recent years; consequently, new cases of ONJ have been reported in association with these drugs, especially if administered with BPs and denosumab. When the drugs are administered alone, ONJ is rarely seen. The objective of our study was to analyze the recent literature relative to the association of ONJ with these new drugs highlighting the pathogenic, clinical and therapeutic aspects. The close collaboration between maxillofacial surgeon, oncologist, dentist, and dental hygienist remains the most important aspect for the prevention, prompt recognition, and treatment of this pathology.
Angiogenesis Modulating Agents ; Cooperative Behavior ; Denosumab ; Dental Hygienists ; Dentists ; Diphosphonates ; Humans ; Immunomodulation ; Immunotherapy ; Jaw ; Oral and Maxillofacial Surgeons ; Oral Manifestations ; Osteonecrosis ; Pathology

Dyke-Davidoff-Masson syndrome is a non-inherited rare condition that presents during childhood and is characterized by seizures, hemiplegia, mental retardation, cerebral hemiatrophy, calvarial thickening, and hyperpneumatization of the frontal sinuses. The present article highlights a case of a 12-year-old male child with additional clinical findings of café-au-late pigmentation and ocular lipodermoid. This is the first case report of Dyke-Davidoff-Masson syndrome to describe oral manifestations, such as unilateral delayed eruption of teeth, hypoplasia, and taurodontism, which could be unique and characteristic of this condition. Oral health care providers and physicians should be aware of these oral observations as dental referrals could warrant early dental prophylactic care and can be useful in diagnosing the possible time of injury and type of Dyke-Davidoff-Masson syndrome.
Child ; Dental Enamel Hypoplasia ; Frontal Sinus ; Hemiplegia ; Humans ; Intellectual Disability ; Male ; Open Bite ; Oral Health ; Oral Manifestations* ; Pigmentation ; Referral and Consultation ; Seizures ; Tooth

oral cavity has been known to be less common one among oral manifestations of AIDS. The authors experienced a case of CMV infection on tongue of an AIDS patient. Thirty eight years old male developed a lesion on the dorsal surface and tip of tongue, manifesting superficial painful ulcer, and complained of the mouth discomfort. The histopathological features showed changes within the vascular endothelial cells : that is, extremely swollen cells with intracytoplasmic and intranuclear inclusions. Periodic acid-Schiff(PAS) and Gomori's methenamine silver(CMS) stains showed more prominent inclusions. The immunohistochemical stain using cytomegalovirus antibody(CMV Ab) showed strong positivity So it seems to us that was a good example of oral CMV infection in AIDS patient. Therefore we report one case of CMV stomatitis in AIDS patient.]]>
Coloring Agents ; Cytomegalovirus ; Endothelial Cells ; Humans ; Intranuclear Inclusion Bodies ; Male ; Methenamine ; Mouth ; Oral Manifestations ; Stomatitis ; Tongue ; Ulcer

Oral features include repeated occurrence of blisters, erosions, and scars, which lead to limited mouth opening, ankyloglossia, elimination of buccal vestibule, and increased risk of oral carcinoma. Routine dental care or even normal tooth brushing might cause bullae on the oral mucosa. Occasionally, the clinician will be called upon to treat patients with EB and should therefore be aware of specific treatment modifications. we present a reviews of the literature with a case providing adequate anesthetic and surgical care.]]>
Blister ; Cicatrix ; Dental Care ; Epidermolysis Bullosa ; Genetic Heterogeneity ; Humans ; Mouth ; Mouth Abnormalities ; Mouth Mucosa ; Oral Manifestations ; Phenotype ; Skin ; Tooth

Treating patients with severely worn dentition often requires comprehensive prosthetic treatments. Oral rehabilitation and long-term stability could be achieved by analyzing the cause of the wear and changing vertical dimension. The temporary restoration procedure is executed and patient's adaptation is evaluated by long-term observation when treatment is accompanied with increasing vertical dimension. In this case, 54 year-old male presented with worn dentition and esthetic dissatisfaction. In oral manifestations, severely worn dentition with attrition and erosion is diagnosed. To evaluate change of vertical dimension, interocclusal rest space, facial appearance, pronunciation, clinical crown length, distance from incisor edge to labial vestibule are evaluated. Consequently, 2.5 mm increase of vertical dimension that based on articulator incisal pin is determined. After 8 weeks stabilization period with temporary prostheses, definitive prostheses are fabricated. After 6 months follow up period, satisfactory outcomes were achieved both in functional and esthetic aspects through this procedure.
Crowns ; Dental Articulators ; Dentition* ; Follow-Up Studies ; Humans ; Incisor ; Male ; Mouth Rehabilitation* ; Oral Manifestations ; Prostheses and Implants ; Rehabilitation ; Tooth Wear ; Vertical Dimension*

Migraine without aura was significantly frequent in Beh et's disease patients. While, the relationship of TAC(trigeminal autonomic cephalalgia) and Beh et's disease was not known. And, it is thought that pathogenesis of proxysmal headache with autonomic features in neuroBehcet's disease as our case may be different from those of clust headache and TAC. A 45-year-old male admitted with left sided periobital poxysmal headache accompained by ipsilateral conjunctival injection and lacrimination with autonomic features. T2WMR image showed about 1.5x2.6x2.6 cm sized mass with high signal intensity surrounded by a rim of low signal intensity in pons. Enhanced MR image showed enhancing mass-like lesion inside the T2 high signal intensity. CSF study revealed neutrophilic pleocytosis with normal pressure, protein and glucose concentration. No malignant cell were seen. Antiphospholipid antibody and cryoglobuline was significantly increased. 3 days after hospitalvisit, oral ulcerations appeared in the patient. He was treated with high-dose steroid for a week and his headache and abnormal findings of CSF study became fully recovered. Two weeks later, the mass was nearly reduced in the pons on follow-up MR image. We suggest to include a careful interviewfor 2ndary TAC as the first neurologic symptom in the diagnostic work-up of Behet's disease.
Antibodies, Antiphospholipid ; Brain Stem* ; Brain* ; Follow-Up Studies ; Glucose ; Headache* ; Humans ; Leukocytosis ; Male ; Middle Aged ; Migraine without Aura ; Neurologic Manifestations ; Neutrophils ; Oral Ulcer ; Pons ; Trigeminal Autonomic Cephalalgias