1.Risk factors of peri-implantitis: a narrative review
Oral Biology Research 2024;48(2):31-36
Implant biological complications like peri-mucositis and peri-implantitis are still common in clinical practice. Peri-implantitis is a disease characterized by bleeding during the probe procedure, swelling, redness, or exudate of the gingiva around the implant, and bone loss. It is an irreversible disease, and while various treatments have been tried, the results have not always been positive. The implant can be placed in the alveolar bone on the buccolingual, vertical, or horizontal sides. Several studies have found a link between the position of the implant and peri-implantitis. Although the findings of the preceding studies are convincing in theory, the placement of implants in clinical practice is influenced by various circumstances. To overcome the difficulties that may arise during implant placement, dentists must make various efforts, from diagnosis to surgical procedures.
2.Surgical treatment of medication-related osteonecrosis of the jaw in patients with autoimmune diseases
Young Hoon KANG ; Na Young LEE
Oral Biology Research 2024;48(2):45-51
This retrospective, single-center study compares the factors influencing the surgical outcomes of medication-related osteonecrosis of the jaw (MRONJ) in patients with and without autoimmune diseases (AIDs). The total surgical success rate was 92% during the mean 2-year follow-up period, and treatment failure was observed in 8% of all patients without AID and 12% of patients with AIDs. Bisphosphonate duration and administration route (intravenous) were found to be risk factors of MRONJ. A careful treatment plan should be developed with a multidisciplinary team including a rheumatologist and a maxillofacial surgeon to avoid the use of drugs that may adversely affect treatment results when MRONJ occurs in patients with AIDs.
3.Use of digital surgical guides for esthetic crowns in anterior teeth:a case report
Jeong-Woo YUN ; Ji-Han KIM ; Joon-Seong KIM ; Yu-Ri HEO ; Mee-Kyoung SON
Oral Biology Research 2024;48(2):58-67
The shape of the maxillary anterior teeth is an essential factor in esthetics because this region is prominently exposed during conversations and smiles, significantly influencing one’s impression. Moreover, the form and color of the gingiva in the anterior teeth play a vital role in determining esthetics. Therefore, various factors should be considered when improving the esthetics of the maxillary anterior teeth. This report is aimed at introducing the use of digital devices and software to analyze various factors, determining the amount of gingival and alveolar bone resection in a patient with esthetically unpleasing maxillary anterior teeth due to a gummy smile or gingival asymmetry. Furthermore, this study describes the method for creating a digital surgical guide using CAD software for esthetic crown lengthening and reports on the achieved esthetic improvements.
4.Peripheral NLR family pyrin domain-containing 3 protein pathway participates in the development of orofacial inflammatory pain in rats
Myung-Dong KIM ; Yu-Mi KIM ; Jo-Young SON ; Jin-Sook JU ; Dong-Kuk AHN
Oral Biology Research 2024;48(2):37-44
The study aimed to investigate the role of peripheral NLR family pyrin domain-containing 3 protein (NLRP3) in inflammatory pain development in the orofacial area. Male Sprague–Dawley rats were used in experiments, with orofacial formalin-induced pain behavior and complete Freund’s adjuvant (CFA)-induced thermal hyperalgesia as chronic inflammatory pain models. Administration of 5% formalin produced biphasic nociceptive behavior, and subcutaneous pretreatment with MCC950 (50 and 100 μg/50 μL), an NLRP3 inhibitor, remarkably attenuated nociceptive behavior during the second phase. Subcutaneous CFA injection induced thermal hyperalgesia 1 day after injection, which persisted for 7 days. Five days after CFA injection, subcutaneous treatment with MCC950 (50 and 100 μg/50 μL) significantly attenuated thermal hyperalgesia. Additionally, subcutaneous injection of BMS-986299 (50 and 100 μg/50 μL), an NLRP3 agonist, induced significant nociceptive behavior for 1 hour in naïve rats. Pretreatment with an interleukin-1β (IL-1β) receptor antagonist blocked the nociceptive behavior produced by subcutaneous injection of BMS-986299 (100 μg/50 μL);however, treatment with a hypoxia-inducible factor 1α inhibitor did not. These findings suggest the involvement of the peripheral NLRP3 and IL-1β pathway in chronic inflammatory pain development in the orofacial area, highlighting the potential of blocking this pathway as a strategy for developing future inflammatory pain treatment drugs.
5.Effect of a metallic ultrasonic scaler tip on titanium surfaces:a preliminary study
Min-Cheol YANG ; Seok-Hwan JEONG ; Hyun-Min LEE ; Seung-Hwan SEOL ; Seung-Kyu LEE ; Sang-Joun YU ; Byung-Ock KIM
Oral Biology Research 2024;48(2):52-57
The present study aims to evaluate the effect of a metallic magnetostrictive ultrasonic scaler tip on titanium surfaces. Eighteen identical disks were investigated, 12 (1-untreated and 3-treated group) for surface roughness and 6 for weight change. The power settings of the conventional insert were fixed as high, medium, and low in the blue zone. Surface topography analysis was conducted via scanning electron microscopy (SEM). Furthermore, surface roughness measurements of treated and untreated surfaces were compared using a profilometer. The profilometer showed different roughness findings depending on the applied power. SEM results showed that the damaged height was more pronounced from low to high power. Additionally, the weight change of the titanium was affected by the power setting. Therefore, the power setting must be carefully selected when using this scaler in clinical practice. Moreover, an in vitro study must be conducted under various clinical conditions in the future.
6.Central odontogenic fibroma case report
Su-Wan KIM ; Jae-Seek YOU ; Gyeong-Yun KIM ; Dong-Ho SHIN
Oral Biology Research 2024;48(1):26-30
Central odontogenic fibroma (COF) is a rare tumor, accounting for only 0.1% of all odontogenic tumors of the jaw. Clinically, these tumors grow slowly and expand the cortical bone without causing pain. Radiographically, they typically appear as unilocular radiolucent lesions with relatively well-defined linings, although multilocular lesions can also be observed. In some cases, the lesion may lead to root resorption of affected teeth and increased tooth mobility. The standard treatment for COF is surgical excision.However, due to its rarity, the optimal approach regarding affected tooth extraction remains unclear. In this report, we present cases of COF in 58- and 56-year-old females, outlining the diagnostic workup, treatment strategy, and postoperative outcomes, particularly regarding affected tooth extraction. Through this case study, we aim to contribute to the existing literature on COF management and achieve successful treatment outcomes.
7.Effect of different head positions on three-dimensional facial images
Jun-Hee YOON ; Do-Gil KIM ; Seungwon OH ; Jin-Hyoung CHO ; Min-Hee OH
Oral Biology Research 2024;48(1):7-14
The purpose of this study was to determine whether head posture affects three-dimensional (3D) facial images. This study evaluated facial images of 10 mannequins, which are taken from standard postures, left and right rotations, and up and down rotations. The images with changed head posture were superimposed onto standard head posture image, and the difference between the two images was used to evaluate deformations in images with the changed head postures. The 3D facial images showed considerable differences depending on different head positions.
8.The underrated role of cold drinks in post-tonsillectomy care:a pediatric case study
Oral Biology Research 2024;48(1):22-25
The benefits of traditional techniques like cold dissection, hot methods, and suturing for reducing post-tonsillectomy complications such as swelling, pain, and bleeding have been established, however, the postoperative advantages of consuming cold drinks remain underappreciated. This case study aims to highlight the beneficial effects of cold-water consumption in post-tonsillectomy care. An 11-year-old girl suffering from mild rhinitis and severe chronic mouth breathing underwent tonsillectomy. Her postoperative care regimen involved standard instructions coupled with daily intake of cold beverages. This approach resulted in the complete healing of the intraoral wound, without necessitating additional painkillers. Histopathological evaluation revealed right tonsillar hyperplasia laden with bacterial colonies and hyperplasia in the left tonsil. The consumption of cold beverages or ice cream post-tonsillectomy is a promising alternative for postoperative care in pediatric patients. It prompts an organized spontaneous healing process at the wound site and helps pain management.
9.Surgical treatment of mandibular first premolar with radicular groove:periradicular microsurgery
Yoorina CHOI ; Sue A KIM ; Kkot Byeol BAE ; Hoon-Sang CHANG
Oral Biology Research 2024;48(1):15-21
This study aimed to report the results of a successful periradicular microsurgery on a mandibular first premolar with a radicular groove. A 38-year-old female reported a sinus tract on her buccal gingiva which was radiographically traced to the middle third of the mesial side of the root of her mandibular right first premolar (#44). A radicular groove and an accessory canal in the middle of the radicular groove were found using cone-beam computed tomography. After endodontic treatment, the sinus tract did not disappear;thus, periradicular microsurgery was performed. The radicular groove and the accessory canal were prepared and filled with fastsetting MTA without resectioning the root apex. After 3 weeks, the sinus tract disappeared, and complete healing was revealed on the periapical radiograph at a 5-month follow-up. Therefore, periradicular microsurgery is recommended in mandibular first premolars with radicular grooves on the accessible mesial side of the root.
10.Accuracy of implant installation using screw hole position analysis
Sun-Haeng LEE ; Ha-Rim LEE ; Gyeong-Je LEE
Oral Biology Research 2024;48(1):1-6
Dental implants are accepted as an effective treatment tools; however, they have a biomechanically disadvantageous structure compared with natural teeth. To compensate for the structural limitations of dental implants, occlusal must be considered to minimize the stress applied to the implants. This study aimed to verify whether the basic biomechanical principle that stress should be applied along the long axis of the implant fixture could be appropriately applied to actual implant clinical treatment. To evaluate whether the major axis of the implant is located at the center of the occlusion surface, the location of the screw hole was analyzed using the image of the stereolithographic file formed during the digital laboratory process, and the accuracy of implant placement was confirmed indirectly.The study included 261 patients and 392 implant cases. By tooth type, the numbers of samples were 57 in the first premolar, 66 in the second premolar, 152 in the first molar, and 117 in the second molar. The location of the screw hole was analyzed by dividing the occlusion surface of the implant crown into nine grids of the same size based on the outermost boundary. Consequently, the accuracy of implant placement tended to decrease from the premolar to the molar, upper jaw to the lower jaw, and left to right.