Noncontact tonometer is a convenient instrument for checking of intraocular pressure without corneal touch. We compared the IOP of 45 eyes in 24 patients with and without soft contact lenses. Two measurements were taken on each eye while the patients were wearing soft conbtact lenses by noncontact tonometry, and rechecked immediatly after the lenses were removed. There was no significant differance between two measurements(t-test, P>0.05).
Contact Lenses, Hydrophilic* ; Humans ; Intraocular Pressure* ; Manometry*

UV-absorption method was able to determine protease activities in various kinds of enzymatic cleaners. Bioclen G and O2 had high protease activeities at room temperature and were effective for artificial protein deposits; Bioclen G is safe for the eyes because enzyme was inactivated at 70 degrees C. Both products were better enzymatic cleaners for both hard and soft contact lenses. Hydrocare-F was effective for removing artificial protein deposits. For the sake of safety against the eyes, there was a problem in that this product had too high protease activity at 90 degrees C. Protease activities were generally lower or showed great variations at 10~30 degrees C for other products. These had lower cleaning effect for artificial protein deposits on rigid gas permeable contact lenses.
Contact Lenses* ; Contact Lenses, Hydrophilic

UV-absorption method was able to determine protease activities in various kinds of enzymatic cleaners. Bioclen G and O2 had high protease activities at room temperature and were effective for artificial protein deposits; Bioclen G is safe for the eyes because enzyme was inactivated at 70 degrees C. Both products were better enzymatic cleaners for both hard and soft contact lenses. Hydrocare-F was effctive for removing artificial protein deposits. For the sake of safety against the eyes, there was a problem in that this product had too high proteasea activity at 90 degrees C. Protease activities were generally lower or showed great variations at 10 ~ 30 degrees C for other products. These had lower cleaning effect for artificial protein deposits on rigid gas permeable contact lenses.
Contact Lenses* ; Contact Lenses, Hydrophilic

PURPOSE: To investigate the accuracy of intraocular pressure (IOP) measurement through a plano soft contact lens (SCL) in situ by a noncontact tonometer (NCT) and a rebound tonometer (RBT). METHODS: The IOP of 66 eyes of 33 subjects with no ocular pathology was measured by NCT (tonometer CT-80, TOPCON, Japan) and RBT (iCare rebound tonometry(TM), Tiolat Oy, Finland). IOP measurement was repeated through plano SCL (ACUVUE OASYS(R), Johnson & Johnson Vision Care Inc., USA) in situ. Statistical analysis was performed using the paired t-test. RESULTS: Mean IOP measured by NCT was 13.10 +/- 2.52 mmHg without SCL and 12.95 +/- 2.56 mmHg with SCL. Mean IOP measured by RBT was 14.13 +/- 2.94 mmHg without SCL and 13.84 +/- 2.75 mmHg with SCL. No significant statistical differences were found between IOP measured with and without SCL (p=0.47, p=0.11 respectively). CONCLUSIONS: Reliable measurement of IOP by NCT and RBT can be achieved through plano SCL.
Contact Lenses, Hydrophilic ; Eye ; Intraocular Pressure ; Vision, Ocular

Soft Contact Lenses(SCL) are used widely instead of glasses among young female, especially university students, for cosmetic purpose. Usually Shirmer test has been used to evaluate the tear production state however more objective method is the tear film break up time. Authors evaluated the effect of soft contact lenses on BUT. We selected 40 femalse wearing on Hyper-Thin soft contact lenses, and One Soflens(Baush and Lomb) as soft contact lens wearing group and 30 females without no evidence of systemic disease or ocular disease affecting on tear production as normal control group. And authors studied mean value of BUT at each group, difference of BUT between 2 groups and finally evaluated the BUT change accord ing to duration of wearing. The results were as follows. 1. The mean value of tear film break up time(BUT) was 8.64 +/- 3.91 seconds and 11.12 +/- 4.94 seconds in soft contact lens wearing group and normal control group respectively. 2. There was a statistically significant difference of BUT between each group(P<0.05). 3. There was statistically significant difference of BUT between more than 4 years of soft contact lens wearing group and less than 3 years of wearing gorup(P<0.05).
Contact Lenses, Hydrophilic* ; Eyeglasses ; Female ; Glass ; Humans ; Tears*

The times of uptake and release of pilocarpine solution by soft contact lenses were studied with spectrophometer in vitro. The uptake time was about 30 minutes and the releasing time was stationary after 30 minutes. The lower concentriction of pilocarpine solution was generally rapid uptake and release than higher.
Contact Lenses, Hydrophilic* ; Pilocarpine*

The purpose of the study was to evaluate a modified technique of Goldmann applanation tonometry without the use of fluorescein and anesthesia in normal eyes with soft contact lenses (SCLs) and to compare this technique with the conventional method. Fifty eyes were measured using Goldmann applanation tonometer. A mean intraocular pressure(IOP)was 17.5 +/-2.33mmHg by the conventional technique and 15.2 +/-2.35 mmHg by the modified technique. We found the IOPvalues of the modified method were consistently underestimated IOP levels by approximately 2.3 mmHg than those of the conventional method (R=0.86, p<0.05). This bias appears to be affected by the fluorescent dye, not affect-ed by the presence of SCL. Our results suggest that the measurements by the modified technique can reflect the IOP measured by conventional method with correction factor of+2 .3 mmHg. The modified technique is a very convenient and simple screening method to measure IOP in patients wearing SCLs, without need for removal or staining of lenses.
Anesthesia ; Bias (Epidemiology) ; Contact Lenses, Hydrophilic* ; Fluorescein ; Humans ; Intraocular Pressure* ; Manometry ; Mass Screening

Intraocular pressure detection has a great significance for understanding the status of eye health, prevention and treatment of diseases such as glaucoma. Traditional intraocular pressure detection needs to be held in the hospital. It is not only time-consuming to doctors and patients, but also difficult to achieve 24 hour-continuous detection. Microminiaturization of the intraocular pressure sensor and wearing it as a contact lens, which is convenient, comfortable and noninvasive, can solve this problem because the soft contact lens with an embedded micro fabricated strain gauge allows the measurement of changes in corneal curvature to correlate to variations of intraocular pressure. We fabricated a strain gauge using micro-electron mechanical systems, and integrated with the contact lens made of polydimethylsiloxane (PDMS) using injection molding. The experimental results showed that the sensitivity was 100. 7 µV/µm. When attached to the corneal surface, the average sensitivity of sensor response of intraocular pressure can be 125.8 µV/mm Hg under the ideal condition.
Contact Lenses, Hydrophilic ; Dimethylpolysiloxanes ; Glaucoma ; Humans ; Intraocular Pressure ; Tonometry, Ocular ; instrumentation

Corneal sensitivity was measured with the Cachet-Bonnet aesthesiometer in control group of 24 people with 24 eyes and in 36 people with 56 eyes who had worn daily wear soft contact lenses for various amount of years. The sensitivity in the control cornea of the normal eyes was 59 +/- 4mm and decreased gradually by duration in myopic patients with daily wear soft contact lenses. And corneal sensitivity in old aged group was lower than that in young aged group.
Contact Lenses, Hydrophilic* ; Cornea ; Humans

We evaluated the effects of piggyback contact lens that override the hard contact lens over soft contact lens for irregular astigmatic correction. Two patients received corneal suture for corneal laceration and one patient received penetrating keratoplasty for Francois dystrophy. The uncorrected visual acuity was counting fingers at 20cm, 0.05, and 0.08, respectively and corrected visual acuity using glasses or conventional contact lens was 0.1, 0.2, and 0. 2, respectively. The difference of keratometry reading between two meridians is 6, 7.5, and 12.5 diopters, respectively. The visual acuity after piggyback contact lens fitting was 0.4, 0.9, and 0.3, respectively. The complication such as corneal ederna, corneal erosion, and neovascularization of cornea was not noted during 24 months after piggyback contact lens fitting. The piggyback contact lens fitting inay be an effective method of correcting visual acuity for irregular astigmatism.
Astigmatism* ; Contact Lenses, Hydrophilic ; Cornea ; Eyeglasses ; Fingers ; Glass ; Humans ; Keratoplasty, Penetrating ; Lacerations ; Meridians ; Sutures ; Visual Acuity