1.Risk Factors Of Newly Diagnosed Hypertension Among Individuals In Malaysia
Malaysian Journal of Public Health Medicine 2018;18(2):57-69
The aim of this study is to examine the influence of risk factors which include modifiable and non-modifiable risk factors on the likelihood of newly diagnosed hypertension among Malaysians. A cross-sectional population-based survey: The Fourth National Health and Morbidity Survey (2011) was conducted by the Ministry of Health, Malaysia in 2011. The sample included 20,095 participants. This study uses binomial logistic regression techniques to predict the likelihood of modifiable and non-modifiable risk factors of newly diagnosed hypertension among the individuals. The analysis has been carried out by estimating odds ratio with 95% confidence interval. This study reveals that obese and overweight respondents as well as current drinkers have increased chances of having newly diagnosed hypertension. In contrast to that, only physically inactive respondents exhibit lower odds of newly diagnosed hypertension. Besides that, the significant predictors, which include older respondents, retirees and home makers, as well as lower educated respondents are respectively found to be more likely to have newly diagnosed hypertension. On the other hand, female respondents, urban dwellers, including the Chinese and Indian respondents, the highest income earners and underweight respondents have been found to have statistically significant lower odds of newly diagnosed hypertension. Through the insightful findings and evidence, this research provides a platform for the early detection and prevention of newly diagnosed hypertension. Hence, this study offers a means to monitor and control the increasing prevalence of newly diagnosed hypertension in Malaysia.
Newly diagnosed hypertension
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prevention
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modifiable risk factors
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non-modifiable risk factors
2.The Risk Factors for Undiagnosed and Known Hypertension among Malaysians
Malaysian Journal of Medical Sciences 2019;26(5):98-112
Background: The prevalence of known hypertension has resulted from the progression of
undiagnosed hypertension. This study is targeted to examine and compare the risk factors based
on the estimated odds ratios of modifiable and non-modifiable risk factors on different outcome
levels of hypertension.
Methods: A nationwide representative secondary data from the Fourth National Health of
Morbidity Survey (NHMS IV) which consists of 24,632 non-institutionalised Malaysian population
conducted by the Ministry of Health in 2011 has been used. Odds ratio (OR) with 95% confidence
interval has been estimated using multinomial logistic regression.
Results: Obese and overweight respondents exhibit increased likelihood of having
undiagnosed and known hypertension. Physically inactive, ex-smokers and unclassified drinkers
are found having higher likelihood to have known hypertension. However, current drinkers
are found to have higher likelihood of having undiagnosed hypertension. Elderly, retirees,
home makers and lower educated respondents are shown higher odds to have undiagnosed
hypertension. Likewise, the likelihood of having known hypertension has been found to increase
among the elderly and other Bumiputra.
Conclusion: Through this research, significant predictors which consist of obese and
overweight respondents, current drinkers, older respondents (above 65 years old) and primary
educated respondents are having higher likelihood to have undiagnosed hypertension.
3.Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn's disease in Asia
Choon Jin OOI ; Ida HILMI ; Rupa BANERJEE ; Sai Wei CHUAH ; Siew Chien NG ; Shu Chen WEI ; Govind K MAKHARIA ; Pises PISESPONGSA ; Min Hu CHEN ; Zhi Hua RAN ; Byong Duk YE ; Dong Il PARK ; Khoon Lin LING ; David ONG ; Vineet AHUJA ; Khean Lee GOH ; Jose SOLLANO ; Wee Chian LIM ; Wai Keung LEUNG ; Raja Affendi Raja ALI ; Deng Chyang WU ; Evan ONG ; Nazri MUSTAFFA ; Julajak LIMSRIVILAI ; Tadakazu HISAMATSU ; Suk Kyun YANG ; Qin OUYANG ; Richard GEARY ; Janaka H DE SILVA ; Rungsun RERKNIMITR ; Marcellus SIMADIBRATA ; Murdani ABDULLAH ; Rupert WL LEONG ;
Intestinal Research 2019;17(3):285-310
The Asia-Pacific Working Group on inflammatory bowel disease (IBD) was established in Cebu, Philippines, under the auspices of the Asian Pacific Association of Gastroenterology with the goal of improving IBD care in Asia. This consensus is carried out in collaboration with Asian Organization for Crohn's and Colitis. With biologic agents and biosimilars becoming more established, it is necessary to conduct a review on existing literature and establish a consensus on when and how to introduce biologic agents and biosimilars in the conjunction with conventional treatments for ulcerative colitis (UC) and Crohn's disease (CD) in Asia. These statements also address how pharmacogenetics influence the treatments of UC and CD and provide guidance on response monitoring and strategies to restore loss of response. Finally, the review includes statements on how to manage treatment alongside possible hepatitis B and tuberculosis infections, both common in Asia. These statements have been prepared and voted upon by members of IBD workgroup employing the modified Delphi process. These statements do not intend to be all-encompassing and future revisions are likely as new data continue to emerge.
Adalimumab
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Asia
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Asian Continental Ancestry Group
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Biological Factors
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Biosimilar Pharmaceuticals
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Colitis
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Colitis, Ulcerative
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Consensus
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Cooperative Behavior
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Crohn Disease
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Gastroenterology
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Hepatitis B
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Humans
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Immunologic Factors
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Inflammatory Bowel Diseases
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Infliximab
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Pharmacogenetics
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Philippines
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Practice Guidelines as Topic
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Tuberculosis
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Ulcer