Resuscitation is the medical process of reviving a patient in cardiac arrest or impending cardiac arrest. In this paper, we describe some of the resuscitation research conducted by our group. The discussion will include: using Geographic Information Systems (GIS) technology to describe the geographic epidemiology of pre-hospital cardiac arrest in Singapore, therapeutic post resuscitation hypothermia, and automated cardio-pulmonary resuscitation (CPR) using a load-distributing band (LDB) device.
Cardiopulmonary Resuscitation - Education

INTRODUCTIONExercise-related cardiac arrest is uncommon, however it is devastating when it occurs in otherwise healthy adults. This study aims to identify the characteristics of exercise-related cardiac arrest in the study population and estimate the overall survival rate.

MATERIALS AND METHODSThis is a retrospective observational study of exercise-related cardiac arrest in Singapore. Patients with exercise-related out of hospital cardiac arrest (OHCA) were selected from the Cardiac Arrest and Resuscitation Epidemiology (CARE) database, which is a prospective cardiac arrest registry, derived from ambulance records, emergency department and hospital discharge records. Patient characteristics, cardiac arrest circumstances and outcomes were studied.

RESULTSFifty-fi ve cases of exercise-related cardiac arrests were identified from December 2001 to January 2008. Mean age was 50.9 years with a male predominance of 96.4%. Eighty percent of the exercise-related cardiac arrests were witnessed, however only 58.2% of the patients received bystander cardiopulmonary resuscitation (CPR). The fi rst presenting rhythm was ventricular fibrillation (VF) in 40% of the patients, followed by asystole (38.2%). Of 96.2% of the patients who died from cardiac causes, coronary artery disease was the main etiology for 54%. The 30-day survival rate was 5.5%.

CONCLUSIONWe found that exercise-related cardiac arrest causes significant mortality in our community. Increased CPR training among the public, easy access to defibrillators and faster emergency medical service (EMS) response time could improve the outcome of exercise-related cardiac arrests. A comprehensive pre-participation screening for competitive exercises should be outlined for primary prevention of exercise-related cardiac arrest. A better reporting system for exercise-related cardiac arrest is needed.

Adolescent ; Adult ; Age Factors ; Aged ; Cardiopulmonary Resuscitation ; utilization ; Exercise ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Out-of-Hospital Cardiac Arrest ; epidemiology ; Retrospective Studies ; Singapore ; epidemiology ; Young Adult

A 77-year-old Chinese female patient presented with acute onset of left lower limb paraesthesia and weakness after she received an intramuscular injection for pain relief in the gluteal region. Magnetic resonance (MR) imaging of her lumbosacral spine and sacral plexus was performed. The MR imaging findings are reviewed and discussed.
Aged ; Female ; Humans ; Iatrogenic Disease ; Injections, Intramuscular ; adverse effects ; Magnetic Resonance Imaging ; Sciatic Neuropathy ; diagnosis ; etiology

INTRODUCTIONHaemolysis of blood samples is a common problem encountered in the Emergency department (ED). It leads to inaccurate blood results and has cost implications as blood samples very often have to be retaken. The purpose of our study was to determine which factors in blood sampling were associated with higher rates of haemolysis.

MATERIALS AND METHODSAn observational convenience sample of all patients presenting to the ED requiring blood urea and electrolyte (UE) analysis were eligible for our study. Questionnaires were distributed to the doctors and nurses conducting blood sampling to determine the method used and outcome data were collected after the samples were processed.

RESULTSOut of 227 UE samples analysed, 45 (19.8%) were haemolysed. Various factors, including method (IV cannulation or venepuncture), system (syringe or vacutainer), operator, rate of blood flow, difficulty of cannulation/venepuncture and source of blood (arterial or venous), were analysed, but their effects on haemolysis were not statistically significant (P >0.05). However, the use of the vacutainer system was associated with the highest rates of haemolysis [adjusted odds ratio (OR), 6.0; 95% confidence interval (CI), 2.3 to 15.1].

CONCLUSIONWe found blood sampling with the vacutainer system to have increased rates of haemolysis. This could potentially change attitudes towards equipment used for blood sampling in the ED.

Catheters, Indwelling ; Data Collection ; Emergency Service, Hospital ; Hemolysis ; Humans ; Nurses ; Phlebotomy ; instrumentation ; methods ; Physicians ; Professional Competence ; Singapore ; Syringes ; utilization

INTRODUCTIONIntraosseous access is an alternative to conventional intravenous access when access is difficult or impossible in the adult population. The EZ-IO is a novel intraosseous access device designed for use in adults, utilising a powered driver.

MATERIALS AND METHODSA prospective, observational study involving a convenience sample of 25 medical students, physicians and nursing staff recruited as study subjects to secure intraosseous access using the EZIO powered drill device, on a bone model.

RESULTSTwenty-three (92%) of the 25 study subjects required only 1 attempt at placing the EZ-IO. There were 24 (96%) successful placements of the EZ-IO. The average time taken to place the EZ-IO was 13.9 seconds. Twenty (87%) of 23 participants reported easier placement with the EZ-IO than an intravenous cannula. The average time taken for the physicians, nursing staff and medical students was 3.71 (+/- SD 1.70) seconds, 7.88 (+/- SD 4.02) seconds and 33.7 (24.5), respectively. Overall mean difficulty of insertion score (VAS) was 3.1 (+/- SD 1.9).

CONCLUSIONThe intraosseous access device evaluated in this study appears to be easy to use with high success rates of insertion with inexperienced participants. There is potential for use in the Emergency Department.

Adult ; Catheterization, Peripheral ; instrumentation ; Catheters, Indwelling ; Equipment Design ; Humans ; Infusions, Intraosseous ; instrumentation ; Professional Competence ; standards ; Prospective Studies ; Resuscitation ; methods ; Shock ; therapy

BACKGROUND: This study was undertaken to validate the use of the modified early warning score (MEWS) as a predictor of patient mortality and intensive care unit (ICU)/ high dependency (HD) admission in an Asian population. METHODS: The MEWS was applied to a retrospective cohort of 1024 critically ill patients presenting to a large Asian tertiary emergency department (ED) between November 2006 and December 2007. Individual MEWS was calculated based on vital signs parameters on arrival at ED. Outcomes of mortality and ICU/HD admission were obtained from hospital records. The ability of the composite MEWS and its individual components to predict mortality within 30 days from ED visit was assessed. Sensitivity, specificity, positive and negative predictive values were derived and compared with values from other cohorts. A MEWS of ≥4 was chosen as the cut-off value for poor prognosis based on previous studies. RESULTS: A total of 311 (30.4%) critically ill patients were presented with a MEWS ≥4. Their mean age was 61.4 years (SD 18.1) with a male to female ratio of 1.10. Of the 311 patients, 53 (17%) died within 30 days, 64 (20.6%) were admitted to ICU and 86 (27.7%) were admitted to HD. The area under the receiver operating characteristic curve was 0.71 with a sensitivity of 53.0% and a specificity of 72.1% in addition to a positive predictive value (PPV) of 17.0% and a negative predictive value (NPV) of 93.4% (MEWS cut-off of ≥4) for predicting mortality. CONCLUSION: The composite MEWS did not perform wel in predicting poor patient outcomes for critical y il patients presenting to an ED.

INTRODUCTION: Atrial fibrillation (AF) with rapid ventricular rate (RVR) is a common diagnosis in the Emergency Department (ED) requiring evaluation and treatment. We present the characteristics and outcomes of patients presenting with primary or secondary AF in a tertiary hospital ED. MATERIALS AND METHODS: This retrospective cohort study included consecutive patients ≥21 years old, with a primary or secondary diagnosis of AF with RVR in the ED over a 1-year period from 1 January 2016 to 31 December 2016. Primary AF is defined as AF with no precipitating cause and secondary AF as AF secondary to a precipitating cause. RESULTS: A total of 464 patients presented to the ED from 1 January to 31 December 2016 with primary and secondary diagnosis of AF with RVR; 44.8% had primary diagnosis of AF whereas 55.2% had secondary AF. Overall admission rate from ED was high at 91.8% (primary 84.6% vs secondary 97.7%). Patients with primary AF were younger (68 vs 74 years, <0.001), had lower rates of cardiovascular risk factors, and shorter length of stay (median 4 vs 5 days). Within 30 days of discharge, they had lower ED reattendance (16.3% vs 25.8%, <0.001) and lower readmission (16.3% vs 25.8%, <0.001). There was no mortality in the primary AF group (0% vs 9.8%, <0.001). CONCLUSION Currently, majority of patients with AF with RVR are admitted from the ED. Other study suggests patients with uncomplicated primary AF have lower adverse outcomes and some could potentially be treated as outpatients.
Aged ; Atrial Fibrillation ; diagnosis ; epidemiology ; therapy ; Emergency Service, Hospital ; statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Outcome and Process Assessment (Health Care) ; Patient Care Management ; methods ; statistics & numerical data ; Patient Readmission ; statistics & numerical data ; Retrospective Studies ; Risk Factors ; Singapore ; epidemiology ; Tachycardia, Ventricular ; diagnosis ; epidemiology ; therapy ; Tertiary Care Centers ; statistics & numerical data

No abstract available.
Cardiopulmonary Resuscitation*

PURPOSE: We evaluated the influence of time-related input, throughput, and output factors on ambulance diversions in an urban emergency department (ED). METHODS: Data was prospectively collected in an urban ED for one year. We measured daily input factors (daily number of visit, etc), throughput factors (ED length of stay), and output factors (occupancy rate of adult ward, etc). The duty emergency physician had the authority to declare an ambulance diversion. There was no written protocol for ambulance diversion, and each diversion lasted 4 hours if not extended. We estimated the effect of the potential factors of the same day and the previous day on ambulance diversion with a multivariates logistic regression analysis excluding variables with collinearity RESULTS: The total annual number of visits was 40,863. The number of patients delivered by ambulance was 4,059 (9.9%). Ambulance diversion occurred 29 times during 365 twenty-four hour observation intervals (7.9%). The multivariates logistic regression analyses revealed three significant independent factors of ambulance diversion: the ward occupancy rate of the previous day (odds ratio [OR], 1.278; 95% confidence interval [CI], 1.039-1.573), the elderly proportion for the day (OR, 1.106; 95% CI, 1.005-1.217), the total number of visits of the day (OR, 1.079; 95% CI, 1.039-1.120). CONCLUSION: Daily number of visits, proportion of elderly, and ward occupancy rate of the previous day were found to be factors related with ambulance diversion, with the hospital occupancy rate of the previous day showing the highest OR.
Adult ; Aged ; Ambulances ; Crowding ; Emergencies ; Emergency Service, Hospital ; Humans ; Logistic Models ; Prospective Studies ; Time Factors

A 50-year-old Chinese man presented to the clinic with left hypochondrial pain, more than 10 kg of weight loss over a 3-month period, and a firm, large, ill-defined mass in the left upper quadrant. Contrast-enhanced computed tomography of the abdomen and pelvis revealed a well-circumscribed exophytic pancreatic mass with features suggestive of acinar cell carcinoma (ACC). The patient underwent chemotherapy and radiotherapy, with no evidence of local recurrence detected at one-year follow-up. He remains under close surveillance by his oncologist. Treatment for ACC includes surgical resection with adjuvant radiotherapy. Better overall survival is seen in patients with surgically resectable ACC as compared to those with the more common ductal cell carcinoma.
Carcinoma, Acinar Cell ; diagnostic imaging ; pathology ; Humans ; Male ; Middle Aged ; Pancreatic Neoplasms ; diagnostic imaging ; pathology ; Tomography, X-Ray Computed