PURPOSE: To evaluate the role of MRI in the management of cervical cancer treated by conventional four-field whole pelvic irradiation. METHOD AND MATERIAL: Between 1993-march and 1994-february, 20 patients(4 Stage I B, 3 Stage U A, 13 Stage U B) with invasive cervical cancer were eligible for evaluation of accuracy of conventionally designed lateral treatment field without MRI determination. RESULTS: 5 out of 20 Patients had inadequate margin without MRI. The position of uterine fundus was more important than cervix in correction of field size and the center of treatment field. CONCLUSION: This Preliminary date show MRI determination of uterine position prior to radiotherapy planning is essential in the case of four-field whole pelvic irradiation technique.
Cervix Uteri ; Female ; Humans ; Magnetic Resonance Imaging* ; Radiotherapy* ; Uterine Cervical Neoplasms*

No abstract available.
Induction Chemotherapy*

MR imaging of the brain in 34 patients were reviewed to characterize the MR findings of brain damage due to perinatal hypoxic insult All the patients had a history of perinatal hypoxia and showed abnormal brain MR findings. Out of 34, eight infants were born premature and twenty-six were born at term or post-term. MR findings were analysed for the extent and location of abnormalities of the white matter, cortical abnormality. Corpus callosum atrophy, and abnormal progression of myelination. The major abnormalities were abnormal signal lesions or atrophy of the cerebral white matter and gyral atrophy of the cerebral cortex. The distribution of white matter lesions well correlated with maturity of the brain at the time of hypoxic insult. Periventricular and deep white matter lesions predominated in the premature-born patients. Corpus callosum atrophy was frequently seen. Reflecting the location of white matter injury. Delay in myelination was present in 55%. MR is a very useful diagnostic imaging modality and guide for the prediction of prognosis by accurate depiction of the location and extent of brain damage due to perinatal hypoxic insult.
Anoxia* ; Atrophy ; Brain* ; Cerebral Cortex ; Corpus Callosum ; Diagnostic Imaging ; Humans ; Infant ; Magnetic Resonance Imaging ; Myelin Sheath ; Prognosis ; White Matter

No abstract available.

The authors reported one case of toxic epidermal necrolysis that occurred in the carbamazepine treatment in a 47-year old male patient with aggressive organic mental disorder. This case developed toxic epidermal necrolysis while taking carbamazepine with a dose of 600mg/day. Toxic epidermal necrolysis did not improve after discontiuation of carbamazepine. We reviewed incidence and the natural history of toxic epidermal necrolysis.
Alcoholism ; Carbamazepine ; Cluster Analysis ; Neurocognitive Disorders ; Humans ; Incidence ; Male ; Middle Aged ; Natural History ; Stevens-Johnson Syndrome*

No abstract available.
Angioplasty* ; Child* ; Humans ; Takayasu Arteritis*

Purpose: There are a variety of techniques for treating chronic prostatitis. Regardless of the presence of infections, antibiotics were arbitrarily prescribed for 4-12 weeks, but there seemed to be ongoing debate of their effectiveness and side effects. Uro-vaxom(R) is known as an effective treatment for urinary tract infection due to its initiation the urothelial immune system activity. This study was performed to investigate for the possibility of Uro-vaxom(R) as a drug for use in non-inflammatory chronic prostatitis. Materials and Methods: 95 patients, diagnosed as chronic pelvic pain syndrome (CPPS) (National Institutes of Health (NIH)-category IIIB), were divided into three groups: group A, 35 patients were given levofloxacin 100mg TID and Uro-vaxom(R) 60mg OD for the first 4 weeks, followed by only Uro-vaxom(R) 60mg OD for the next 8 weeks; group B, 30 patients were given only Uro-vaxom(R) 60mg OD before breakfast for 12 weeks; group C, the patients were treated with levofloxacin 100mg TID for 4 weeks. All the patients were reevaluated 4 weeks and 12 weeks later. Results: The initial diagnostic stati, the NIH-Chronic Prostatitis Symptom Index (CPSI) were 25.1+/-2.7, 24.4+/-3.2 and 24.7+/-2.2 for groups A, B and C, respectively. In groups A and B, the NIH-CPSI after 12 weeks were 13.5 2.3 and 13.9+/-2.7, respectively, and showed noticeable improvements (p<0.05). In group C, the NIH-CPSI was 15.7+/-3.4, which was less improved compared to groups A and B (p>0.05). No patients experienced any adverse symptoms due to Uro-vaxom(R) intake. Conclusions: Uro-vaxom(R) could be appointed as an alternative method for the treatment of chronic prostatitis.
Academies and Institutes ; Anti-Bacterial Agents ; Breakfast ; Humans ; Immune System ; Levofloxacin ; Pelvic Pain* ; Prostatitis ; Urinary Tract Infections ; Urinary Tract*

Latex is the milky sap obtained by tapping the rubber tree, Hevea brasiliensis. The prevalence of latex allergy has been on the increase alongside the wider use of latex-manufactured products. The number of reports of latex-induced anaphylaxis during operation is therefore increasing. We report the case of a 56-year-old male patient who developed severe anaphylactic shock while under anesthesia when the tourniquet was deflated during elbow arthrolysis. A subsequent allergy workup revealed an IgE-mediated hypersensitivity to latex.
Anaphylaxis ; Anesthesia ; Elbow ; Hevea ; Humans ; Hypersensitivity ; Hypersensitivity, Immediate ; Latex ; Latex Hypersensitivity ; Male ; Middle Aged ; Prevalence ; Tourniquets

Eccrine spiradenoma is a rare benign tumor which is differentiated into the direction of eccrine gland. Neurofibromatosis type-1 is an autosomal dominantly inherited disorder that is characterized by neurofibroma, cafe au lait spots and axillary freckles of the skin. We report a case of a 42-year-old man with a painful, solid nodule on his right arm for 4~5 months. He was diagnosed with neurofibromatosis type-1 in childhood. He has several cafe au lait spots and diffuse freckles on whole body. On microscopy, the tumor was sharply demarcated with encapsulated lobules in the dermis. The lobules consisted of two undifferentiated epithelial cells. There was hyperpigmentation of the basal cell layer in the epidermis without increase in the number of melanocyte. We herein report an unusual case of eccrine spiradenoma in neurofibromatosis type-1 patient.
Adult ; Arm ; Cafe-au-Lait Spots ; Dermis ; Eccrine Glands ; Epidermis ; Epithelial Cells ; Humans ; Hyperpigmentation ; Melanocytes ; Melanosis ; Microscopy ; Neurofibroma ; Neurofibromatoses ; Skin

BACKGROUND: Varicella is a disease caused by varicella zoster virus with vesicular skin eruption. Usually the symptom improves automatically though there have been rare cases, that developed serious complications. It can be prevented by immunization with live attenuated varicella vaccine. But among immunized children "breakthrough varicella" has been reported in about 5~20%. OBJECTIVE: The aim of this study is to evaluate the effects of live attenuated varicella vaccine on clinical course of varicella. METHODS: A total of 104 varicella patients were divided into two groups; vaccinated and unvaccinated. We evaluated patients about the demographic characters and clinical features of varicella through interview and medical examination. Because varicella is more serious in adolescents and adults, we also divided the patients into two groups by age of 12 for male and 10 for female. RESULTS: The immunized group showed a statistically noticeable distinction. The patients showed more mild prodromal symptoms, small amount of rash in oral mucosa, and on the palms and soles. Small counts of total skin lesion and less itching were observed. They also required a shorter period of hospital treatment and disease duration. CONCLUSION: Immunization is known to decrease the incidence of varicella, but the study also confirmed that immunization can weaken serious symptoms in breakthrough varicella.
Adolescent ; Adult ; Chickenpox ; Chickenpox Vaccine ; Child ; Exanthema ; Herpesvirus 3, Human ; Humans ; Immunization ; Incidence ; Male ; Mouth Mucosa ; Prodromal Symptoms ; Pruritus ; Skin ; Vaccination