No abstract available.
Anemia* ; Cross-Sectional Studies* ; Female* ; Humans ; Prevalence*

PURPOSE: This study was describes the development and implementation a sex education program with a blended learning method for university students. METHODS: Sixty-eight university students were recruited either to the experimental group (n=35) or the control group (n=33). This program was developed based on the analysis, design, development, implementation, and evaluation model. The analysis phase consisted of a literature review, focus group interview, expert consultations, and target group survey. In addition, learning objectives and structure were designed, and a printed text-book, presentation slides, cross-word puzzle, and debate topics were developed. In the implementation phase, the program was conducted 3 times over the course of 3 weeks. The evaluation phase involved verification of the effects of the program on sex-related knowledge, sexual autonomy, and justification of violence, as well as an assessment of satisfaction with the program. RESULTS: The experimental group had significantly higher scores on sex-related knowledge (t=5.47, p < .001), sexual autonomy (t=2.40, p=.019), and justification of violence (t=2.52, p=.015) than the control group. CONCLUSION: The results indicate that this sex education program with blended learning was effective in meeting the needs of university students and can be widely used in this context.
Focus Groups ; Humans ; Learning* ; Methods ; Referral and Consultation ; Sex Education* ; Violence

No abstract available.
Immunohistochemistry ; Keratins

Bilateral segmental neurofibromatosis is a rare disease characterized by bilateral neurofibromas, with or without pigmented lesion, or unilateral neurofibromas with contralateral pigmented lesion, limited to a body segment. Partial unilateral lentiginosis is characterized by numerous lentigines localized to a body segment, often corresponding to one or more dermatome. Bilateral segmental neurofibromatosis combined with partial unilateral lentiginosis is very rare, and to our knowledge, only 2 cases have been reported in English literature. We herein report another case of bilateral segmental neurofibromatosis with partial unilateral lentiginosis in a 46-year-old woman.
Female ; Humans ; Lentigo* ; Middle Aged ; Neurofibroma ; Neurofibromatoses* ; Neurofibromatosis 1 ; Rare Diseases

PURPOSE: The purposes of this study were to identify body image changes and physical suffering during radiotherapy among breast cancer patients following breast conserving operations and establish correlations between the two. METHODS: Twenty seven patients were recruited in this survey design. Patient interviews and patient-reported questionnaires were used to collect data from March 1 to July 30, 2013. The questionnaire included 18 items about body image and 10 items about physical suffering. RESULTS: Patients' body image during radiotherapy following breast conserving operation turned significantly negative. Likewise, patients' physical suffering increased significantly during radiotherapy. Body image and physical suffering were inversely correlated (p=.031). CONCLUSION: Breast cancer patients receiving radiotherapy following breast conserving operations go through changes in body image. Timely and proper interventions for physical suffering during radiotherapy would help to set up and maintain a positive body image.
Body Image* ; Breast Neoplasms* ; Breast* ; Humans ; Radiotherapy* ; Surveys and Questionnaires

No abstract available.
Antibodies* ; Korea* ; Prevalence* ; Rubella*

PURPOSE: The purpose of this study was to identify factors that affect reality shock in new nurses. METHODS: Participants were 216 newly graduated nurses with less than 1 year experience in 5 university and 10 general hospitals in Busan, Ulsan and Gyeongnam, A self-report questionnaire was completed by the nurses between November 18 and December 25, 2013. Data were analyzed using t-test, ANOVA and hierarchial multiple regression analysis with the SPSS/WIN 21.0 Program. RESULTS: Average scores for work environment and environmental reality shock were 2.63+/-0.33 and 2.66+/-0.43 points respectively. Regression analysis showed that with the nurses' demographic and work characteristics controlled, work environment explained 4.2% of the reality shock. Factors significantly affecting reality shock included nurses' changing residence because of job (beta=.21, p=.001), whether they were able to work on the unit of their choice (beta=-.13, p=.031) and whether they had a choice in days off (beta=-.14, p=.038). CONCLUSION: When these factors are considered, reduction in nurses' reality shock requires improvement in work environment, placing new nurses in a department of their choice and allowing them a choice in off-duty days. These measures would also help achieve organizational goals and develop the new nurses as professional nurses.
Busan ; Hospitals, General ; Organizational Objectives ; Surveys and Questionnaires ; Shock* ; Ulsan

In this study, we investigated the anticancer activity of the fin of Thunnus Thynnus (TT ). TT was extracted with methanol (TTM ), and then further fractionated into four subfractions by using solvent partition method, affording hexane (TTMH ), methanol (TTMM ), butanol (TTMB )and aquous (TTMA )soluble fractions. We determined the cyto-toxicity of these four fractions in four kind of cancer cell lines, such as HepG2, MCF-7, B16-F10 and HT29 by MTT assay. The TTMM showed the strongest cytotoxic effect at the concentration of 150 microgram/mL, displaying 95% on the HepG2 cell lines and 82% on MCF-7 cell line. The morphological changes such as membrane shirinking and blebbing of cells were also observed by TTMM treatment in HT29 cell. In addition, we observed that quinone reductase (QR ) activity was elevated by only TTMM and TTMH treatments in HepG2 cell. QR activity was increased to around 2.0 and 1.8 times in TTMM and TTMH treated HepG2 cell at 100 microgram/mL, respectively, compared to that in control. Although further studies are needed, the present work could suggest that the fin of TT has a potential to be usable as a chemo-preventive agent against cancer.
Blister ; Cell Line ; Hep G2 Cells ; HT29 Cells ; Humans ; MCF-7 Cells ; Membranes ; Methanol ; NAD(P)H Dehydrogenase (Quinone)*

Celastrus orbiculatus (CO) has been used as a traditional herb medicine to treat fever, chill, joint pain, edema, rheumatoid arthritis and bacterial infection in China and Korea. In this study, we investigated anticarcinogenic effects of Celastrus orbiculatus (CO). CO was extracted with methanol (COM), and then further fractionated into four different types: methanol (COMM), hexane (COMH), butanol (COMB) and aqueous (COMA) partition layers. We determined the cytotoxicity of these four partitions in four kind of cancer cell lines, such as HepG2, MCF-7, HT29 and B16F10 Cells by MTT assay. Among various partition layers of CO, the COMM showed the strongest cytotoxic effects on cancer cell lines we used. We also observed quinone reductase (QR) induced effects in all partition layers of CO on HepG2 cells. The QR induced effects of COMM on HepG2 cells at 80 microgram/mL concentration indicated 3.28 to a control value of 1.0. The COMM showed the highest induction activity of quinone reductase on HepG2 cells among the other partition layers. Although further studies are needed, the present work suggests that CO may be a chemopreventive agent for the treatment of human cells.
Anticarcinogenic Agents ; Arthralgia ; Arthritis, Rheumatoid ; Bacterial Infections ; Celastrus* ; Cell Line ; China ; Edema ; Fever ; Hep G2 Cells ; Humans ; Korea ; Methanol ; NAD(P)H Dehydrogenase (Quinone)*

PURPOSE: This study was to examine the effects of Taping therapy on the deformed angle of the foot and pain in hallux valgus patients. METHOD: The subjects were 24 feet from 15 patients who were diagnosed withhallus valgus at the orthopedic department of K University Hospital in Seoul. Taping therapy was conducted 15 times overall during a four-week period. Data was analyzed using descriptive statistics and t-test. RESULT: The deformed angle of the foot of the hallus valgus patients significantly improved from 21.95(4.38) to 18.75(4.80) after Taping therapy. Pain significantly decreased from 4.73(1.56) to 3.45(2.21) after Taping therapy. CONCLUSION: The result shows that Taping therapy is effective in improving the deformed angle of the foot and in decreasing pain in the hallux valgus patients.
Adult ; Female ; Hallux Valgus/*therapy ; Humans ; Middle Aged ; *Orthotic Devices ; Pain