To address the possible prognostic value of p53 and Bcl-2 proteins in non-small cell lung carcinomas (NSCLCs), the authors studied 43 cases of NSCLCs diagnosed between the years 1990 to 1995 at Pusan National University Hospital. The patients were treated either by pneumonectomy or lobectomy of the lung. The expression of p53 and Bcl-2 proteins was semiquantitatively analyzed in paraffin sections by immunohistochemical method and correlated with clinicopathologic prognostic parameters of NSCLCs. Overexpression of the p53 protein was found in 31 cases (72.1%) of the 43 NSCLCs. Overexpression of the p53 protein was significantly correlated with the decreasing degree of histologic differentiation, increasing tumor stage, and cigarette smoking. Bcl-2 expression was found in 19 cases (44.2%) of the 43 NSCLCs. Increased expression of the Bcl-2 protein was significantly correlated only with decreasing tumor stage. An inverse relationship was found between p53 and Bcl-2 proteins, but it was not statistically significant. Thus p53 and Bcl-2 proteins, as demonstrated immunohistochemically in routine paraffin sections, could be of value in prediction of the aggressiveness and prognosis of NSCLCs, in agreement with the central role of p53 and Bcl-2 proteins in the evolution of NSCLCs associated with cigarette smoking.
Busan ; Humans ; Immunohistochemistry ; Lung* ; Paraffin ; Pneumonectomy ; Prognosis ; Smoking

No abstract available.
Coronary Vessels*

PURPOSE: The purpose of this study is to verify the effects of the Qigong training program on the anxiety and labor pains of primipara. METHOD: The research subjects were a total of 60 primipara who consulted a doctor regularly concerning their antenatal care. Among them, 30 people were the experimental group, and the other 30 people were the control group, and were selected as homogeneous with the experimental group. The degree of anxiety and labor pains were measured by State-Trait Anxiety Inventory(STAI) and Graphic Rating Scale(GRS). SPSS WIN 11.0 was used for data analysis. Obstetric and general characteristics between experimental and control groups, and a homogeneity test of state and trait anxiety were done by both X2 test and t-test. The hypothesis testing was analyzed by ANCOVA with a covariate of pretest value. RESULT: The first hypothesis, 'Primipara who join the Qigong training program have lower anxiety than those who do not join' was supported (F=28.8, p<.000). The second hypothesis, 'Primipara who join the Qigong training program have lower labor pain than those who do not join' was unsupported. CONCLUSION: It was verified that the Qigong training program was effective in alleviating anxiety; however it did not have any effect on relieving labor pain, so more in-depth research is needed later on.
Anxiety* ; Education* ; Female ; Humans ; Labor Pain* ; Pregnancy ; Qigong* ; Research Subjects ; Statistics as Topic

No abstract available.
Hepatitis E virus* ; Hepatitis E* ; Hepatitis* ; Korea*

No abstract available.
Humans ; Quintuplets*

PURPOSE: The purpose of this study was to describe and explore the experience process of life of patients with Crohn's disease. METHODS: Using a grounded theory methodology, 24 interviews were performed with 7 men and 5 women, 17-47 years of age, suffering from Crohn's disease. RESULTS: 'Tuning of two conflicting lives' was identified as the core category, and 5 subcategories were identified and they were integrated into the core category. The identified outcomes were 'Living a withdrawn life', 'coping flexibly', 'drifting with tangled emotions' and 'maintaining long-term remission'. CONCLUSION: When caring for these patients, it is important to identify needs, allow patients to express what they want at that moment and support them in maintaining a daily life that can be perceived as normal.
Adaptation, Psychological ; Adolescent ; Adult ; Crohn Disease/*psychology ; Female ; Humans ; Interviews as Topic ; *Life Change Events ; Male ; Middle Aged ; Stress, Psychological ; Young Adult

No abstract available.

PURPOSE: This study was done to investigate the point prevalence of postpartum depression and its predictors during early postpartum in mother of preterm infants. METHODS: Participants were 101 women, 2-3 weeks after delivery whose preterm babies were hospitalized in a neonatal intensive care unit. Data were collected from June 2010 to January 2011. The instruments included 'Edinburgh Postnatal Depression Scale', 'Prenatal depression', 'Subjective health status of infant', 'Medical staff support', and 'Husband support'. Collected data were analyzed using t-test, chi2-test, and multiple logistic regression with SPSS/WIN version 18.0. RESULTS: The point prevalence was 86.1% that postpartum depression occurred during the early postpartum period in mothers of preterm infants. Three significant predictors of postpartum depression in mothers of preterm infants were identified; 'Type of delivery (OR, 5.57; 95% CI, 1.25-24.77)', 'Subjective health status of infant (OR, 0.34; 95% CI, 0.16-0.70)', and 'Medical staff support (OR, 0.52; 95% CI, 0.28-0.97)'. CONCLUSION: The results indicate that postpartum mothers should be screened for postpartum depression early in the postpartum period and that, medical personnel should pay particular attention to mothers with a caesarean section and should help mothers of preterm babies to develop positive perceptions of their babies.
Cesarean Section ; Depression, Postpartum* ; Female ; Humans ; Infant ; Infant, Newborn ; Infant, Premature* ; Intensive Care Units, Neonatal* ; Intensive Care, Neonatal ; Logistic Models ; Mothers* ; Postpartum Period ; Pregnancy ; Prevalence

It is commonly believed that the branchial anomalies are persistent remnants of the embryologic branchial apparatus. These anomalies are originated from branchial cleft and most commonly involved in second branchial deft. Clinically they present palpable mass, discharge from fistula, recurrent infection due to obstruction of Gstula tract. As respiratory symptoms, they may present hoarseness, preceeded by or associated with upper respiratory infection. However, it has not been reported that they caused airway obstruction in newborn infants. Wc experienced a case of the fourth branchial deft cyst in a 2 day old infant who showed respiratory difficulty due to airway obstruction.
Airway Obstruction ; Branchial Region* ; Branchioma* ; Fistula ; Hoarseness ; Humans ; Infant ; Infant, Newborn

Recently, the number of obese people have been increasing due to westernized diets and increased sedentary activity. In particular, obese adolescent have been newly recognized as having significant health problems. This study focuses on determining the gender difference of obese adolescents through implementation of a structured questionnaire on general characteristics, attitudes toward dieting, eating habits and emotional depression due to obesity. Data collection was carried out by 291 students in attendance at 3 high schools in Pusan from 11. 2. 1998 to 11. 30. 1998. The targes were 148 boys and 143 girls who were judged as obese in the school's physical check-up. The test of reliability of this research was calculated by chronbach's alpha . Data analysis was managed by computer and statistics by SPSS/WIN. The results of the survey are as follows: 1.For the questionnaire regarding attitudes toward dieting which include 28 items, 10 out of 28 items (about 36%)showed gender difference. 2. For the questionnaire regarding eating habits which include 17 items, 5 out of 17 items (about 30%)showed gender difference. 3.For the questionnaire regarding emotional depression about obesity, 30.6% of boys and 27.3% girls answered but no statistical significance. The results of this survey indicated that this study will be important as a good guideline for treating obese adolescents. It is hoped that much more research on gender difference in obese adolescents will be implemented in the future. In addition, the development of effective treatments for obesity should be based on the gender of the adolescent.
Adolescent* ; Busan ; Data Collection ; Depression* ; Diet* ; Eating* ; Female ; Hope ; Humans ; Obesity ; Statistics as Topic ; Child Health ; Surveys and Questionnaires