A case of fibroepithelial polyp with stromal atypia in a 25-year-old female is described. The tumor arose from the vaginal wall and measured 3.5 cm in maximal diameter. It was composed of hypercellular connective tissue stroma and focal myxoid area containing numerous atypical mono- and multinucleated stromal cells. These cells may mislead to make a diagnosis of sarcoma, particulary of botryoid rhabdomyosarcoma.
Adult ; Connective Tissue ; Diagnosis ; Female ; Humans ; Polyps* ; Rhabdomyosarcoma ; Sarcoma ; Stromal Cells* ; Vagina*

No abstract available.
Diabetes Insipidus* ; Diagnosis*

No abstract available.
Infarction* ; Liver*

Multiple myeloma is a primary malignant tumor of bone marrow characterized by proliferation of cells arising from primitive marrow reticulum that resemble plasma cells. This is one of the most common primary malignant neoplasm involving bone elements. Bone pain, soft tissue mass, low grade fever, anemia, neurologic symptom and renal insufficiency are the main clinical pictures. Authors present radiological and clinical findings of multiple myeloma in 10 cases of pathologically proved multiple myeloma. The results obtained are as follows; 1. In the age and sex distributions, all cases are over 45 years of age, and male to female is 7:3. 2. Clinical manifestations are bone pain, anemia, infection, weight loss, and bleeding. 3. Radiological findings are numerous punched out osteolytic lesions, generalized osteoporosis & osteolytic change, pathologic compression fractures, fracture only and osteoporosis, lytic and fractures. 4. Laboratory findings are monoclonal gammopathy in serum-electrophoresis, proteinuria, anemia, elevated uric acid in serum, Bence-Jones protein in urine and albumin/globulin ration inverse in serum protein.
Anemia ; Bone Marrow ; Female ; Fever ; Fractures, Compression ; Hemorrhage ; Humans ; Male ; Multiple Myeloma ; Neurologic Manifestations ; Osteoporosis ; Paraproteinemias ; Plasma Cells ; Proteinuria ; Renal Insufficiency ; Reticulum ; Sex Distribution ; Uric Acid ; Weight Loss

Osteosarcoma is a malignant tumor arising from the undifferentiated fibrous tissue of bone and one of the mostcommon pirmary malignant tumors of bone. The diagnosis of osteosarcoma is based one can be diagnosed with areasonable degree of confidence from the conbination of the lesion site, age and radiological findings. This is aclinical and radiological observation of 40 cases of osteosarcoma which were experienced at Chonnam NationalUniversity Hospital, Chosum University Hospital and Kwangju Christian Hospital from 1978 to 1981. The results wereas follows; 1. The peak incidence was in the age group from 10 to 19 years in 21 cases (52.5%). 2. In sexdistribution, male group showed slightly higer incidence than in female group with the ratio of 1.35;1. 3. Themost commonly affected site was proximal tibia(35%). The lesion was found around the knee in 65% of the studiedcases. 4. Increment of the level of serum alkaline phosphase was observed in 25 cases (62.5%), and the averagevalue of serum alkaline phosphature in these cases was 5.6 Bessay Lowry units. 5. Radiographically, osteoblastictype was 14 cases (35%), and soft tissue mass shadow with calcification was observed in 34 cases (85%). 6.Cortical destruction was observed in 30 cases (75%), and soft tissue mass shadow with calcification was observedin 34 cases (85%). 7. Solid periosteal reaction, sunburst periosteal reaction and Codman's triangle were observedin 35%, 57.5% and 22.5% respectively. 8. At the first visit, lung meatastasis was found in 5 cases (12.5%) andinguinal lymphnode metastasis in 2 cases (5%)
Diagnosis ; Female ; Gwangju ; Humans ; Incidence ; Jeollanam-do ; Knee ; Lung ; Male ; Neoplasm Metastasis ; Osteosarcoma ; Sulindac

No abstract available.
DNA* ; Mycobacterium tuberculosis* ; Mycobacterium* ; Polymerase Chain Reaction*

No abstract available.
Panax* ; Saponins* ; Water*

Breast cancer is a common cancer in women and the most common primary tumor metastatic to the skin. Cutaneous metastasis from breast cancer occurs predominently through lymphatic dissemination. Alopecia neoplastica is rare and probably caused by the hematogenous spread of the internal carcinoma. It has diagnostic importance because it may be the first sign of an undiscovered internal malignancy. We report a case of a 40-year-old female who showed alopecia neoplastia secondary to an invasive intraductal carcinoma of the breast.
Adult ; Alopecia* ; Breast Neoplasms* ; Breast* ; Carcinoma, Intraductal, Noninfiltrating ; Female ; Humans ; Neoplasm Metastasis* ; Skin

Sebaceous carcinoma is a rare malignant epithelial tumor and has diverse clinical presentations as well as a variety of histologic patterns. Although the overwhelming majority of sebaceous carcinomas occur on the eyelid, they may also arise where sebaceous gland and hair are found together, but they favor the head and neck. We report a case of sebaceous carcinoma of the umbilicus in a 68-year-old man who had suffered from a long standing recurrent Bowen's disease of 23 years. The recurrent Bowen's disease in this patient appeared to be closely related to multiple arsenic medication 49 years and 39 years earlier. The excised specimen of umbilicus revealed a well demarcated, 1.5x1 cm sized tumor with grey-yellow hue. The tumor was identified as sebaceous carcinoma, which was characterized by lobular and comedo-carcinoma patterns. The tumor cells showed cytoplasmic foamy vacuolation, nuclear pleomorphism, and high mitotic activity. On an Oil-Red-O stain, the tumor cells were found to contain fine lipid droplets. The intracytoplasmic lipid vacuoles were demonstrated by an electron microscopic examination.
Aged ; Arsenic ; Bowen's Disease* ; Carcinoma ; Cytoplasm ; Eyelids ; Hair ; Head ; Humans ; Neck ; Sebaceous Glands ; Umbilicus ; Vacuoles

The wandering spleen is a rare condition, in which the spleen is located in other than the left upper quadrant of the abdomen. The clinical manifestation is variable from asymptomatic to abdominal catastrophy due to torsion of the splenic pedicle. We experienced a case of torsion of wandering spleen in 8-year-old girl who admitted with fever, vomiting, abdominal pain, palpable left abdominal mass. She was diagnosed preoperatively with the aid of abdominal sonography and C.T. scanning. A splenectomy was performed and she made uneventful recovery. The case report illustrates some of the diagnostic and therapeutic considerations pertaining to wandering spleen with a brief review of related literature.
Abdomen ; Abdominal Pain ; Child ; Female ; Fever ; Humans ; Spleen ; Splenectomy ; Vomiting ; Wandering Spleen*