1.The Ultrastructure of Tongue Mast Cells in Bombina orientalis.
Chang Ho SONG ; Hyung Tae KIM ; Ok Hee CHAE ; Sun Ok LEE ; Moo Sam LEE
Korean Journal of Anatomy 1997;30(1):29-34
This study was carried out to observe the ultrastructure of tongue mast cells in frog, Bombina orientalis. In the light microscopy, mast cells were round, oval, spindle-like and irregular shape and occasionally had one or more tail-like long cytoplasmic processes. Mast cells had many red granules stained with toluidine blue in the cytoplasm. In the electron microscopy, mast cells had membrane-bounded granules and poorly developed organelles. The granules were composed of two parts, low and dense electron density. In high magnification the dense part in the middle region of granule had honey comb-like crystalline structure.
Anura*
;
Crystallins
;
Cytoplasm
;
Honey
;
Mast Cells*
;
Microscopy
;
Microscopy, Electron
;
Organelles
;
Tolonium Chloride
;
Tongue*
2.Studies on preparation of 99mTc complexes of methionine isomers.
Ok Doo AWH ; Hee Soon CHANG ; Dong Sun LEE
Korean Journal of Nuclear Medicine 1992;26(1):140-146
No abstract available.
Methionine*
3.The Economic Impact of a Rural Hospital to local Economy.
Im Ok KANG ; Sun Hee LEE ; Han Joong KIM
Korean Journal of Preventive Medicine 1996;29(4):831-842
Demand for high quality medical care has recently been increasing in step with high level of income and education. Patients prefer the use of large general hospitals to small community hospitals. Large hospitals, usually located at urban area, expand their capacities to cope with the increasing demand, therefore, they easily secure revenue necessary for growth and development of hospitals. However, small community hospitals are facing with serious financial difficulties caused from the reduction of patients in one hand and the inflation of cost in another. If small rural hospitals were closed, the closure would have negative impacts on local economies in addition to the decrease in access to medical care. Community leaders should have an insight on the contribution of community hospitals to local economies. They could make a rational decision on the hospital closure only with the understanding of hospital's contribution to the community. This study is designed to develop an economic model to estimate the contribution of rural hospital to local economies, and also to apply this model with a specific hospital. The contribution of a hospital to local economies consists of two elements, direct effect and multiplier effects. The direct impacts include hospital's local purchasing power, employee's local purchasing power, and the consumption of patients coming from outside the community. The direct impact induces multiplication effect in the local economy. The seed money invested to other industries grows through economic activities in the economy. The seed money invested to other industries grows through economic activities in the region. This study estimated the direct effect with the data of expenditure of the case hospital. The total effect was calculated by multiplied the direct effect with a multiplier. The multiplier was drown from the ratio of marginal propensity of income and expenditure. Beside the estimation of the total impacts, the economic effect from the external resources was also analyzed by the use of the ratio of patients coming outside the region. The results are as follows. 1. The direct economic contribution of the hospital to the local economy is 1,104 million won. 2. The value of multiplier in the region is 2.976. 3. The total economic effect is 3,286 million won, and the multiplication effect is 2,182 million won. 4. The economic contribution from the external resources is 245 million won which is 7.5% of the total economic effect.
Education
;
Growth and Development
;
Hand
;
Health Expenditures
;
Health Facility Closure
;
Hospitals, Community
;
Hospitals, General
;
Hospitals, Rural*
;
Humans
;
Inflation, Economic
;
Models, Economic
4.Clinical study on twins.
Sang Hee LEE ; Ok Young KIM ; Son Sang SEO
Journal of the Korean Pediatric Society 1993;36(12):1663-1671
Clinical survey was performed on 413 cases of twin pregnancies and their 816 twin babies who were born at IlSin Christian Hospital during 5years from January 1987 to December 1991. The result of study was as follows: 1) there was 413 twin pregnancies among 40,711 deliveries, so the incidence of twins was 1:98.6. Average male-female sex ratio of twins was 1.3:1, same sex pairs rate was 86% and different sex ratio was 14%. 2) The incidence of relation with maternal age was highest between 25 years old and 29 years old but the ratio of twin delivery to total delivery was 0.9% so, was not higher than other age group. 3) The incidence of relation with maternal parity was highest at first pregnancy but the ratio of twin delivery to total delivery was highest at second pregnancies. 4) Normal birth weight infants were 45.7%, low birth weight infants were 54.3% and very low birth weight infants was 9.3%. Fullt-erm infants were 63.7% and prematurity were 35.4%. 5) The incidence of feto-fetal transfusion was 7.3%. 6) Perinatal death rate was 76.3 and was more higher in second babies. The most common cause of perinatal death was prematurity, followed by respiratory complication, congenital anomaly, infection and asphyxia. Still-births were 8 cases.
Adult
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Asphyxia
;
Birth Weight
;
Female
;
Humans
;
Incidence
;
Infant
;
Infant, Low Birth Weight
;
Infant, Newborn
;
Infant, Very Low Birth Weight
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Maternal Age
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Mortality
;
Parity
;
Pregnancy
;
Pregnancy, Twin
;
Sex Ratio
;
Twins*
5.Factors Influencing Self-Rated Health in Elderly Women in the Community.
Journal of Korean Academy of Fundamental Nursing 2008;15(3):284-290
PURPOSE: This study was done to identify factors that influence self-rated health in elderly women. METHOD: The research design for this study was a descriptive survey design using a convenience sampling method. Data collection was done using a self-questionnaire with 201 women participating in the study. Frequencies, percentages, means, standard deviations, Pearson's correlation coefficients and stepwise multiple regression with the SPSS 10.0 program were used to analyze the data. RESULTS: The age of the women ranged from 65 to 89 and mean was 72.9. The main factors that affected self-rated health were depression, sleep, family APGAR, economic level, social activities and number of illnesses. These variables accounted for 44% of self-rated health. CONCLUSION: The findings of this study provide useful information for constructing intervention programs for elderly women.
Aged
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Data Collection
;
Depression
;
Female
;
Humans
;
Research Design
6.Effects of Postpartum Exercise on Mental Health.
Sun Ok LEE ; Mi Ok KIM ; Suk Hee AHN ; Young Ran CHO
Korean Journal of Women Health Nursing 2004;10(1):15-22
PURPOSE: This study was to examine the effect of postpartum exercise on mental health. Mental health comprises a 9 symptom dimension of Somatization, Obsessive-Compulsive, Interpersonal Sensitivity, Depression, Anxiety, Hostility, Phobic anxiety, Paranoid Ideation, and Psychoticism. METHOD: A non-equivalent pre-test, post-test control group study was conducted. Fifty-two puerperal women who were admitted to a postpartum ward of a mother-baby clinic in Pusan were recruited; 26 women were assigned to the experimental group and 26 women to the control group. Postpartum exercise was applied to the experimental group from postpartum day 3 for a period of 8 weeks while no exercise program was applied to the control group. Mental health with SCL-90-R was measured before and after exercise. Data was analyzed using mean, x2-test, t-test, and ANOVA by SPSS 10.0. RESULT: The mental health status in the exercise group did not show a statistically significant decrease when compared to that of the control group. CONCLUSION: There is no effect of postpartum exercise on women's mental health during the first 8 weeks of the postpartum period. Further studies are needed for randomized clinical trials with a larger sample size.
Anxiety
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Busan
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Depression
;
Female
;
Hostility
;
Humans
;
Mental Health*
;
Postpartum Period*
;
Sample Size
7.Professional Self-Concept and Self-Efficacy according to the Need for Advanced Practice Nurse among Korean Nurses.
Hee Jung JANG ; Soon Ok YANG ; Myung Ok LEE
Journal of Korean Academy of Fundamental Nursing 2007;14(1):110-119
PURPOSE: The purpose of this study was to identify the need for advanced practice nurse and explain the relationship between self-efficacy and professional self-concept among Korean nurses. METHOD: The participants were 511 Korean nurses who were recruited in hospitals or public health centers in Korea. The instruments used in this study were Sherer et al's self-efficacy instrument, Arthur's professional self-concept instrument, and a structured questionnaire on the need for advanced nurse practitioners. Cronbach alpha, mean, SD, X2, t-tests, ANOVA, Pearson correlation coefficient were used to analyze the data using SPSS PC+ ver 12.0 for Windows. RESULTS: Of the nurses, 57.9% of wanted to be advanced practice nurses. The mean of professional self-concept and self-efficacy scores for the nurses were at the medium level. Professional self-concept and self-efficacy of nurses showed significant differences according to age, working location, marital status, level of education, and length of clinical experience. A significant positive correlation was found between professional self-concept and self-efficacy. CONCLUSION: Before planning to develop the role of Advanced practice nurse, there is a need to measure self-efficacy and professional self-concept among nurses. Politically, strategies to increase self-efficacy and professional self-concept among Korean nurses will be necessary in order to prepare good advanced practice nurse.
Education
;
Humans
;
Korea
;
Marital Status
;
Nurse Practitioners
;
Professional Role
;
Public Health
;
Questionnaires
8.Bone Mineral Density, Health-promoting Behaviors, and Self-efficacy in Middle-aged Women.
Geum Hee JEONG ; Soon Ok YANG ; Kwang Ok LEE ; Ok Jung PYE ; Mira LEE ; Sung Hee BAIK ; Kyung Won KIM
Korean Journal of Women Health Nursing 2003;9(2):170-178
To identify osteoporosis and examine the relationship between health behavior and the self-efficacy of middle-aged women, a descriptive survey was conducted. The subjects were 465 healthy female residents of Kyunggido, Korea, who underwent ultrasound measurement and a health examination at the Kangmeung-Ci Health Center between July and August 2000. They were 40 to 60 years old, with a mean age of 46.7 years. The subjects completed a self- reported questionnaire that consisted of seven items concerning health behavior and twelve items concerning self-efficacy related to osteoporosis. Bone density was evaluated from ultrasound measurements of the right heel. All the data were analyzed using the program SAS-PC. The study found that the mean T score related to bone density was -1.30, and ranged from -3.52 to 3.06. Based on the T score, 74.8% of the subjects were normal, 12.9% had osteopenia, and 12.3% had osteoporosis. The mean osteoporosis self-efficacy score was 41.17 and ranged from 12 to 60. Osteoporosis self-efficacy differed significantly with health behavior related to health supplementary food (t=5.63, p=.018), exercise (t=6.65, p=.010), alcohol drinking(t=10.80, p=.001), and smoking (t=10.23, p=.001). A community-based health promotion program should be developed to prevent osteoporosis in middle-aged women.
Bone Density*
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Bone Diseases, Metabolic
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Female
;
Gyeonggi-do
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Health Behavior
;
Health Promotion
;
Heel
;
Humans
;
Korea
;
Middle Aged
;
Osteoporosis
;
Surveys and Questionnaires
;
Smoke
;
Smoking
;
Ultrasonography
10.Decrease of peripheral blood lymphocyte count predicts response to neoadjuvant chemotherapy in breast cancer patients
Korean Journal of Clinical Oncology 2020;16(2):79-88
Purpose:
Pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) holds promise as a significant prognostic factor to predict NAC response in breast cancer patients. The absolute peripheral blood lymphocyte (PBL) count has been suggested as an independent predictor of response to NAC. The current study evaluated the relationship between pCR and the change of PBL count in patients treated with NAC.
Methods:
A total of 61 patients with histologically confirmed breast cancer treated with NAC followed by mastectomy between January 2010 and December 2019 were analyzed retrospectively. Correlational analyses confirmed a statistically significant relationship between PBL count and pCR. Following conformational correlational analyses, patients were divided into two groups according to cutoff values using the receiver operating characteristics curve and a logistic regression was conducted to determine the optimal conditions for achieving pCR.
Results:
A total of 14 patients (22.9%) achieved pCR. Most PBL counts decreased after NAC relevant to pCR. Logistic regression analysis revealed that a small decrease of PBL was associated with pCR (P=0.028). The cutoff value of PBL decrease was 755×106/L, which was used to divide patients into high and low reduction groups. The pCR rate was 11.43% and 38.46% for the high and low reduction group, respectively (area under the curve, 0.707; 95% confidence interval, 0.556–0.858; P=0.020). The high reduction group was found to have more difficulty achieving pCR.
Conclusion
The decrease of PBL is significantly associated with pCR. Our data support that the decrease of PBL after NAC may be useful factors in predicting the response to NAC in breast cancer patients.