1.Extraskeletal Ewing's sarcoma arising in the chest wall.
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(10):1107-1111
No abstract available.
Sarcoma, Ewing*
;
Thoracic Wall*
;
Thorax*
2.Surgical treatment of infective endocarditis.
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(10):1055-1060
No abstract available.
Endocarditis*
3.Treatment of deep thrombosis.
Ok Bo WANG ; Won Gon KIM ; Kyu Seog CHO ; Joo Cheol PARK ; Sae Young YOU
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(11):1358-1361
No abstract available.
Thrombosis*
4.Treatment of the spontaneous pneumothorax by the vertical axillary thoracotomy.
Ok Bo WANG ; Won Gon KIM ; Kyu Seog CHO ; Joo Cheol PARK ; Sae Young YOU
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(11):1282-1285
No abstract available.
Pneumothorax*
;
Thoracotomy*
5.An Usefulness of In Vitro Interferon Gamma Assay for the Diagnosis of Latent Tuberculosis Infection in Middle- and High-School Students in Jeju-Shi, Korea.
Jong Myon BAE ; Eun Hee KIM ; Ok Bo WANG
Tuberculosis and Respiratory Diseases 2010;68(3):155-161
BACKGROUND: The tuberculin skin test (TST) has limitations in diagnosing a latent tuberculosis infection (LTBI). The interferon-gamma release assay (IGRA) was introduced to middle- and high-school students since 2009 by the Korea Centers for Disease Control and Prevention. The aim was to evaluate the utility of IGRA in diagnosing LTBI in middle- and high-school students. METHODS: From August 2007 to July 2009, among suspected LTBI students showing TST induration with a 10 mm diameter and over with a normal chest x-ray in school students of Jeju city, 341 students underwent a Quanti FERON-TB Gold In-Tube (QFT-IT) test to confirm LTBI. RESULTS: From 348 students showing a positive TST, a QFT-IT test was carried out on 341 students. The positive QFT-IT rate was 52.8% (=180/341). The positive QFT-IT rate was higher in high-school boys with a 15~19 mm diameter of induration in TST. CONCLUSION: With the introduction of IGRA for diagnosing LTBI in middle- and high-school students, approximately 47% of students who show a TST induration with a 10 mm diameter and over can avoid taking unnecessary preventive chemotherapy. These results suggest that IGRA is useful for diagnosing and controlling LTBI in Korean students.
Benzeneacetamides
;
Centers for Disease Control and Prevention (U.S.)
;
Disease Outbreaks
;
Humans
;
Interferon-gamma Release Tests
;
Interferons
;
Korea
;
Latent Tuberculosis
;
Piperidones
;
Skin Tests
;
Student Health Services
;
Thorax
;
Tuberculin
6.Localized Tuberculous Pericardial Effusion Collapsing Right Heart.
Hea Ok JUNG ; Pum Joon KIM ; Eun Joo CHO ; Hui Kyung JEON ; Ho Joong YOUN ; Dong Heun KANG ; Ki Bae SEUNG ; Young Pil WANG ; Kyu Bo CHOI
Journal of the Korean Society of Echocardiography 2001;9(2):89-90
No abstract available.
Heart*
;
Pericardial Effusion*
7.Unusual Case of Tuberculosis in Hemodialysis Patient-Tuberculoma Involving Right Atrium.
Young Ok KIM ; Seong Won CHO ; Sang Il KIM ; Young Shin SHIN ; Chul Woo YANG ; Dong Heon KANG ; Young Pil WANG ; Kyu Bo CHOI ; Byung Kee BANG
Korean Journal of Nephrology 1997;16(1):183-187
There is a high incidence of tuberculosis in patients with chronic renal failure undergoing hemodialysis. Clinical features and laboratory findings are intermittent high fever of unknown origin, weight loss, high ESR and CRP. The diagnosis of tuberculosis in patients with hemodialysis can be difficult due to non specific symptoms, insidious onset, and unusually high frequency of extrapulmonary involvement. Sites of extrapulmonary involvement include mediastinum, meninges, pleura, kidney, peritoneum, and rarely pericardium. We experienced a unusual case of tuberculoma involving the right atrium in a hemodialysis patient. Our initial impression of this case was pericardial effusion. However, chest CT and echocardiography revealed a mass on the right atrium. Exploratory thoracotomy revealed tuberculous granuloma scattered throughout pericardium and tuberculoma involving right atrium. Following the administration of anti Tbc medication, clinical symptoms and signs resolved and follow up chest CT showed significant decrease in the size of the tuberculoma.
Diagnosis
;
Echocardiography
;
Fever of Unknown Origin
;
Follow-Up Studies
;
Granuloma
;
Heart Atria*
;
Humans
;
Incidence
;
Kidney
;
Kidney Failure, Chronic
;
Mediastinum
;
Meninges
;
Pericardial Effusion
;
Pericardium
;
Peritoneum
;
Pleura
;
Renal Dialysis*
;
Thoracotomy
;
Tomography, X-Ray Computed
;
Tuberculoma
;
Tuberculosis*
;
Weight Loss
8.Anti-diabetic effect of purple corn extract on C57BL/KsJ db/db mice.
Bo HUANG ; Zhiqiang WANG ; Jong Hyuk PARK ; Ok Hyun RYU ; Moon Ki CHOI ; Jae Yong LEE ; Young Hee KANG ; Soon Sung LIM
Nutrition Research and Practice 2015;9(1):22-29
BACKGROUND/OBJECTIVES: Recently, anthocyanins have been reported to have various biological activities. Furthermore, anthocyanin-rich purple corn extract (PCE) ameliorated insulin resistance and reduced diabetes-associated mesanginal fibrosis and inflammation, suggesting that it may have benefits for the prevention of diabetes and diabetes complications. In this study, we determined the anthocyanins and non-anthocyanin component of PCE by HPLC-ESI-MS and investigated its anti-diabetic activity and mechanisms using C57BL/KsJ db/db mice. MATERIALS/METHODS: The db/db mice were divided into four groups: diabetic control group (DC), 10 or 50 mg/kg PCE (PCE 10 or PCE 50), or 10 mg/kg pinitol (pinitol 10) and treated with drugs once per day for 8 weeks. During the experiment, body weight and blood glucose levels were measured every week. At the end of treatment, we measured several diabetic parameters. RESULTS: Compared to the DC group, Fasting blood glucose levels were 68% lower in PCE 50 group and 51% lower in the pinitol 10 group. Furthermore, the PCE 50 group showed 2- fold increased C-peptide and adiponectin levels and 20% decreased HbA1c levels, than in the DC group. In pancreatic islets morphology, the PCE- or pinitol-treated mice showed significant prevention of pancreatic beta-cell damage and higher insulin content. Microarray analyses results indicating that gene and protein expressions associated with glycolysis and fatty acid metabolism in liver and fat tissues. In addition, purple corn extract increased the phosphorylation of AMP-activated protein kinase (AMPK) and decreased phosphoenolpyruvate carboxykinase (PEPCK), glucose 6-phosphatase (G6pase) genes in liver, and also increased glucose transporter 4 (GLUT4) expressions in skeletal muscle. CONCLUSIONS: Our results suggested that PCE exerted anti-diabetic effects through protection of pancreatic beta-cells, increase of insulin secretion and AMPK activation in the liver of C57BL/KsJ db/db mice.
Adiponectin
;
AMP-Activated Protein Kinases
;
Animals
;
Anthocyanins
;
Blood Glucose
;
Body Weight
;
C-Peptide
;
Diabetes Complications
;
Fasting
;
Fibrosis
;
Glucose Transport Proteins, Facilitative
;
Glucose-6-Phosphatase
;
Glycolysis
;
Inflammation
;
Insulin
;
Insulin Resistance
;
Islets of Langerhans
;
Liver
;
Metabolism
;
Mice*
;
Muscle, Skeletal
;
Phosphoenolpyruvate
;
Phosphorylation
;
Zea mays*
9.De Novo Superinfection of Hepatitis B Virus in an Anti-HBs Positive Patient with Recurrent Hepatitis C Following Liver Transplantation.
Sung Hae HA ; Young Min PARK ; Sun Pyo HONG ; So Ya BACK ; Soo Kyeong SHIN ; Seung Il JI ; Soo Ok KIM ; Wang don YOO ; Bo Hyun KIM ; Sang Jong PARK ; Zheng HONG
Gut and Liver 2011;5(2):248-252
A 60-year-old woman with end stage liver cirrhosis caused by genotype 2 hepatitis C virus (HCV) infection received an orthotopic liver transplantation (OLT). The patient was negative for the hepatitis B surface antigen (HBsAg) and positive for the anti-hepatitis B surface antibody (anti-HBs) prior to and one and a half months following the OLT. Due to reactivation of hepatitis C, treatment with interferon-alpha and Ribavirin started two months following the OLT and resulted in a sustained virological response. We performed a liver biopsy because a biochemical response was not achieved. Surprisingly, liver pathology showed HBsAg-positive hepatocytes with a lobular hepatitis feature, which had been negative in the liver biopsy specimen obtained one and a half months post-OLT. High titers of both HBsAg and HBeAg were detected, while anti-HBs antibodies were not found. Tests for IgM anti-hepatitis B core antibody and anti-delta virus antibodies were negative. The serum HBV DNA titer was over 1x10(7) copies/mL. A sequencing analysis showed no mutation in the "a" determinant region, but revealed a mixture of wild and mutant strains at an overlapping region of the S and P genes (S codon 213 (Leu/Ile); P codons 221 (Phe/Tyr) and 222 (Ala/Thr)). These findings suggest that de novo hepatitis B can develop in patients with HCV infection during the post-OLT period despite the presence of protective anti-HBs.
Antibodies
;
Biopsy
;
Codon
;
DNA
;
Female
;
Genotype
;
Hepacivirus
;
Hepatitis
;
Hepatitis B
;
Hepatitis B e Antigens
;
Hepatitis B Surface Antigens
;
Hepatitis B virus
;
Hepatitis C
;
Hepatocytes
;
Humans
;
Immunoglobulin M
;
Interferon-alpha
;
Liver
;
Liver Cirrhosis
;
Liver Transplantation
;
Middle Aged
;
Ribavirin
;
Superinfection
;
Viruses
10.Salivary mycobiome dysbiosis and its potential impact on bacteriome shifts and host immunity in oral lichen planus.
Yan LI ; Kun WANG ; Bo ZHANG ; Qichao TU ; Yufei YAO ; Bomiao CUI ; Biao REN ; Jinzhi HE ; Xin SHEN ; Joy D VAN NOSTRAND ; Jizhong ZHOU ; Wenyuan SHI ; Liying XIAO ; Changqing LU ; Xuedong ZHOU
International Journal of Oral Science 2019;11(2):13-13
The biodiversity of the mycobiome, an important component of the oral microbial community, and the roles of fungal-bacterial and fungal-immune system interactions in the pathogenesis of oral lichen planus (OLP) remain largely uncharacterized. In this study, we sequenced the salivary mycobiome and bacteriome associated with OLP. First, we described the dysbiosis of the microbiome in OLP patients, which exhibits lower levels of fungi and higher levels of bacteria. Significantly higher abundances of the fungi Candida and Aspergillus in patients with reticular OLP and of Alternaria and Sclerotiniaceae_unidentified in patients with erosive OLP were observed compared to the healthy controls. Aspergillus was identified as an "OLP-associated" fungus because of its detection at a higher frequency than in the healthy controls. Second, the co-occurrence patterns of the salivary mycobiome-bacteriome demonstrated negative associations between specific fungal and bacterial taxa identified in the healthy controls, which diminished in the reticular OLP group and even became positive in the erosive OLP group. Moreover, the oral cavities of OLP patients were colonized by dysbiotic oral flora with lower ecological network complexity and decreased fungal-Firmicutes and increased fungal-Bacteroidetes sub-networks. Third, several keystone fungal genera (Bovista, Erysiphe, Psathyrella, etc.) demonstrated significant correlations with clinical scores and IL-17 levels. Thus, we established that fungal dysbiosis is associated with the aggravation of OLP. Fungal dysbiosis could alter the salivary bacteriome or may reflect a direct effect of host immunity, which participates in OLP pathogenesis.
Adult
;
Bacteria
;
isolation & purification
;
Case-Control Studies
;
Dysbiosis
;
complications
;
microbiology
;
Female
;
Humans
;
Lichen Planus, Oral
;
complications
;
microbiology
;
Male
;
Microbiota
;
Middle Aged
;
Mouth Mucosa
;
microbiology
;
Mycobiome
;
Saliva
;
microbiology