In acupuncture practice of animals, preanesthetics sometimes are needed. The purpose of this study was to select the ideal chemical restraint at acupuncture for gastric motility. Nine healthy mixed breed dogs weighed 10-21 kg and aged 1-3 years old were used in this study. Two EMG surface electrodes were placed between the seromuscular and the mucosal layer of pylorus. Twenty minutes after feeding normal gastric motility was recorded for 60 minutes using physiograph (Narco-Biosystem). Then preanesthetic treated-gastric motility was observed for 30 minutes. Preanesthetics used were xylazine, diazepam, and acepromazine. Acupuncture needles were inserted to BL-21 (Wei-Yu) acupoint, and then changes of gastric motility were recorded for 60 minutes. The gastric motility following xylazine administration (1 mg/kg, IV) was markedly decreased. BL-21 (Wei-Yu) acupoints stimulation did not alter xylazine-induced depression of gastric motility. The diazepam (1 mg/kg IV) treated-gastric motility was increased mildly 20 minutes after drug administration. BL-21 (Wei-Yu) acupoint stimulation after diazepam administration enhanced gastric motility significantly. The gastric motility following acepromazine (0.3 mg/kg, IM) administration was not changed compared with normal gastric motility. Application of traditional acupuncture at BL-21 (Wei-Yu) significantly increased the gastric motility. Based on these results, acepromazine and diazepam could be acceptable chemical restraints for acupuncture therapy of gastric motility, but xylazine couldn't be.
Acepromazine ; Acupuncture/*standards ; *Acupuncture Points ; Adjuvants, Anesthesia ; Adrenergic alpha-Agonists ; Animals ; Antipsychotic Agents ; Atropine ; Diazepam ; Dogs/*physiology ; Dopamine Antagonists ; Electromyography/veterinary ; Gastrointestinal Motility/drug effects/*physiology ; Hypnotics and Sedatives ; Metoclopramide ; Parasympatholytics ; Preanesthetic Medication/standards/*veterinary ; Xylazine

No abstract available.

The authors have intended to measure intrinsic dose distribution by Farmer dosimeter in irregularly shaped fields such as L.M. and T shape models in order to determine dose in homogeneity in those models. We made 2 off-xis points in each model and measured the depth dose at 1.5, 5 and 9cm below surface. The results showed 1~3% dose discrepancy between 2 points. We also measured the depth dose by geometric approximation and computer calculation in those models, and came to the conclusion that computer calculation using Clarkson's principle is simpler and the measurements are closer to the ideal data obtained by the experiment in three models of irregularly shaped fields than those of geometric approximation method.

A primary hepatic sarcoma is a rare tumor, that most frequently arises from hepatic connective tissue or vascular channels, and is usually located in the intrahepatic area. Pedunculated, or bulging, lesions have also been reported. We encountered a pedunculated primary hepatic leiomyosarcoma occurring in a 61-year-old woman. A giant exophytic hepatic mass measuring 15x10cm in size, was located in the left lateral segment of the liver, which was compressing the stomach. A left lateral segmentectomy was performed. Microscopically, the tumor was composed of spindle cells reactive to muscle specific actin. The mitotic figures were 5/10 high power fields indicating the tumor was malignant. No other primary sites were recognized from clinical studies.
Actins ; Connective Tissue ; Female ; Humans ; Leiomyosarcoma* ; Liver ; Mastectomy, Segmental ; Middle Aged ; Sarcoma ; Stomach

Angiomyolipoma is a benign renal tumor composed of thick- walled blood vessels, smooth muscle cells, and adipose tissue. Despite the aggressive biological and histological features associated with angiomyolipoma, the lack of distant metastasis led us to conclude that angiomyolipoma is a benign neoplasm. Epithelioid angiomyolipoma is a recently described variant type of angiomyolipoma of the kidney. Diagnosis is usually made by histological method and immunohistochemical staining with HMB-45. Several reports suggested the presence of malignant epithelioid angiomyolipomas showing multiple metastases and local aggressiveness. We report a case of epithelioid angiomyolipoma with multiple metastases. Local recurrence and liver, bone and lung metastases developed 11 months after radical nephrectomy. Right hepatectomy and wedge resection of left lobe of the liver with radiation therapy were done.
Adipose Tissue ; Angiomyolipoma* ; Blood Vessels ; Diagnosis ; Hepatectomy ; Kidney ; Liver ; Lung ; Myocytes, Smooth Muscle ; Neoplasm Metastasis* ; Nephrectomy ; Recurrence

BACKGROUND AND OBJECTIVES: The aim of our study was to evaluate postoperative mastoid aeration according to the preoperative middle ear disease and investigate the factors affecting it. SUBJECTS AND METHODS: We retrospectively reviewed the high-resolution computed tomography (CT) scans of temporal bones that were taken 1 year after surgery. The postoperative mastoid aeration was evaluated according to the preoperative diagnosis, and classified into three groups: grade 1 (complete mastoid aeration), an air-filled epitympanum and mastoid cavity; grade 2 (partial mastoid aeration), an air-filled epitympanum and partially aerated mastoid cavity; and grade 3 (absence of mastoid aeration), no air space in the mastoid cavity. RESULTS: The overall mastoid aeration rate was 55.8%, with adhesive otitis media accounting for 21.2%, attic cholesteatoma 53.8%, and chronic otitis media 75.4%. The rates of postoperative mastoid aeration were significantly higher in the chronic otitis media cases and attic cholesteatoma cases than in the adhesive otitis media cases. There were 14 cases requiring revision operations due to the development of a retraction pocket in the tympanic membrane. All of the revised cases had grade 3 postoperative mastoid aeration, and underwent canal wall down mastoidectomies. CONCLUSIONS: The degree of postoperative mastoid aeration is associated with the preoperative middle ear disease. When planning a canal wall up mastoidectomy, the surgeon should contemplate the middle ear disease, because a canal wall down mastoidectomy or mastoid obliteration is recommended if the patient has adhesive otitis media.
Adhesives ; Cholesteatoma ; Diagnosis ; Ear, Middle* ; Humans ; Mastoid* ; Otitis Media ; Otologic Surgical Procedures ; Retrospective Studies ; Temporal Bone* ; Tympanic Membrane

BACKGROUND AND OBJECTIVES: The aim of our study was to evaluate postoperative mastoid aeration according to the preoperative middle ear disease and investigate the factors affecting it. SUBJECTS AND METHODS: We retrospectively reviewed the high-resolution computed tomography (CT) scans of temporal bones that were taken 1 year after surgery. The postoperative mastoid aeration was evaluated according to the preoperative diagnosis, and classified into three groups: grade 1 (complete mastoid aeration), an air-filled epitympanum and mastoid cavity; grade 2 (partial mastoid aeration), an air-filled epitympanum and partially aerated mastoid cavity; and grade 3 (absence of mastoid aeration), no air space in the mastoid cavity. RESULTS: The overall mastoid aeration rate was 55.8%, with adhesive otitis media accounting for 21.2%, attic cholesteatoma 53.8%, and chronic otitis media 75.4%. The rates of postoperative mastoid aeration were significantly higher in the chronic otitis media cases and attic cholesteatoma cases than in the adhesive otitis media cases. There were 14 cases requiring revision operations due to the development of a retraction pocket in the tympanic membrane. All of the revised cases had grade 3 postoperative mastoid aeration, and underwent canal wall down mastoidectomies. CONCLUSIONS: The degree of postoperative mastoid aeration is associated with the preoperative middle ear disease. When planning a canal wall up mastoidectomy, the surgeon should contemplate the middle ear disease, because a canal wall down mastoidectomy or mastoid obliteration is recommended if the patient has adhesive otitis media.
Adhesives ; Cholesteatoma ; Diagnosis ; Ear, Middle* ; Humans ; Mastoid* ; Otitis Media ; Otologic Surgical Procedures ; Retrospective Studies ; Temporal Bone* ; Tympanic Membrane

PURPOSE: Chronic pancreatitis is difficult to cure because relapse is common. In particular the removal of stone is very difficult in pancreatolithiasis (pancreatic stone), and is associated with pancreatic duct stenosis. We attempted to evaluate the risk and the outcome of pancreatic resection in chronic pancreatitis. METHODS: We retrospectively reviewed the clinical records of twelve patients with chronic pancreatitis who had undergone pancreatic resection at our hospital between January, 1991 and December, 2000. RESULTS: Pancreaticoduodenectomy was performed in nine cases and distal pancreatectomy in three cases. In the nine cases of pancreaticoduodenectomy, five cases were associated with pancreatolith and four cases were suspected malignancy. In one case of distal pancreatectomy, a pigtail drain was inserted due to postoperative pancreatic leakage. Additionally, one patient who underwent distal pancreatectomy was readmitted one year later due to recurred pancreatitis. The remaining ten patients were discharged without complications and followed up without pain. CONCLUSION: According to two complementary theories (visceral compartment syndorme and neural inflammatory theory), pancreatic resection is better than more conservative treatment, ensuring the elimination of pain. If performed by an expert surgeon, pancreatic resection is a safe and effective treatment for chronic pancreatitis.
Constriction, Pathologic ; Humans ; Pancreatectomy ; Pancreatic Ducts ; Pancreaticoduodenectomy* ; Pancreatitis ; Pancreatitis, Chronic* ; Recurrence ; Retrospective Studies

PURPOSE: Multiple primary cancers are not a rare disease. The clinicopathologic characteristics of a hepatocellular carcinoma with extrahepatic malignancies, have not been identified. To address these points, the clinical data of patients with a hepatocellular carcinoma, with extrahepatic malignancies, treated with surgical resections at our hospital, were retrospectively reviewed. METHODS: We reviewed the clinical records of ten hepatocellular carcinoma patients, with extrahepatic malignancies, who had undergone an operation between January, 1986 and December, 2002 at the Hanyang University Hospital. RESULTS: 10 patients were comprised of 9 males and 1 female, with a mean age of 58.6 years, ranging from 34 to 75. There were 9 stomach cancers and 1 rectal cancer extrahepatic malignancies associated with the hepatocellular carcinomas. Four of these were synchronous type and six were metachronous type. The treatments used for the HCCs were: 1 extended right lobectomy, 6 right lobectomies, 1 each of a TAE with RFTA, a segmentectomy with RFTA, and a segmentectomy. The operations for the extrahepatic malignancies included 1 low anterior resection, for the rectal cancer and 9 subtotal gastrectomies, for the stomach cancers. During the mean follow up time of 66.1 months, five patients survived and five died. CONCLUSION: Patients who have a hepatocellular carcinoma, associated with extrahepatic malignancies, have been treated with aggressive operations and combination therapies. Stomach cancer is the most common extrahepatic malignancy associated with a hepatocellular carcinoma.
Carcinoma, Hepatocellular* ; Female ; Follow-Up Studies ; Gastrectomy ; Humans ; Male ; Mastectomy, Segmental ; Rare Diseases ; Rectal Neoplasms ; Retrospective Studies ; Stomach Neoplasms

Mucoepidermoid carcinoma of the liver is a rare variant of cholangiocarcinoma which contains both mucus-secreting glandular cells and squamous cells mixed in nests. We diagnosed a case of mucoepidermoid carcinoma of the liver in a 69-year-old woman who visited hospital because of fever, chill, right flank pain for one week. On admission, she was not jaundiced. Under a provisional diagnosis of liver abscess, a pigtail catheter was inserted to the abscess cavity. One month after the admission, despite conservative treatment, the abscess cavity remained. For a curative treatment and possible hiden malignancy, right hepatectomy of the liver and excision of partial diaphragm were done. Microscopically, the tumor mass composed of solid and invasive nests of epidermoid and mucin-producing cells with desmoplastic stroma. Alcian blue, Periodic-Acid Schiff (PAS) stainings confirmed the presence of mucin in the cytoplasm of mucus-secreting cells. Electron micrographs showed the presence of tonofilaments and confirmed the squamous nature of the tumor cells. The tumor cells, intrahepatic bile ducts and ductules were consistently reactive with cytokeratin 7. Adjacent nonneoplastic liver cells were negative to cytokeratin 7. In the present case, the tumor was diagnosed as mucoepidermoid carcinoma, which was arisen from the intrahepatic bile duct.
Abscess ; Aged ; Alcian Blue ; Bile Ducts, Intrahepatic ; Carcinoma, Mucoepidermoid* ; Catheters ; Cholangiocarcinoma ; Cytoplasm ; Diagnosis ; Diaphragm ; Female ; Fever ; Flank Pain ; Hepatectomy ; Humans ; Intermediate Filaments ; Keratin-7 ; Liver Abscess* ; Liver* ; Mucins