1.Pharmacological Erection with Prostaglandin E(1) in the Treatment of Chordee or Penile Curvature.
Jun O KWON ; Dong Soo RYU ; Tae Hee OH
Korean Journal of Urology 2001;42(2):154-158
PURPOSE: The artificial erection is critical to chordee repair. We report the use of a natural erection induced by prostaglandin E(1)(PGE1) in the diagnosis and treatment of penile curvatu re as an alternative to artificial erection in children and adult patients. MATERIALS AND METHODS: Pharmacological erection was induced 14 children with a mean age of 5 years (range 1-10) and 8 adults with a mean age of 33 years (range 18-58) to diagnose and repair anomalies, such as simple penile curvature, chordee with or without hypospadias, webbed penis and Peyronie's disease. Alprostadil (1-16ng) as a agent for induce erection was used exclusively, but no agents were routinely given to reverse the erection was used exclusively, but no agents were routinely given to reverse the erections. The dose injected intracavernosally was dependent on the patient's age, penile size and response, and ranged from 0.5 to 10 micrograms. Time to and adequacy of erection, detumescence, changes in blood pressure and pulse rate were monitored. RESULTS: A dilatation of erectile tissue was achieved within 8 minutes and was judged adequate in 2 and excellent in 20. The mean duration of erection was 107 minutes, while a prolonged erection, for up to 2.5 hours, occured on 2 patients who were treated conservatively. Detumescence were occurred when the corpora were opened, but re-erected penis after closure of corpora in 7 cases who treated with Nesbit's corporeal plication or fibrous plaque excision and dermal graft. Although there were the impression of increased bleeding, there were no specific changes in blood pressure or pulse rate. CONCLUSIONS: Pharmacological erection in penile curvature is effective and reliable with no significant complications. Although PGE1 is expensive and induced slightly increased bleeding, pharmacological erection has the advantage of tumescence of the entire penis and consequently a constant and natural representation of chordee without corporeal or urethral injury. Therefore, the erection achieved by injecting PGE1 into the corpora cavemosa is a useful alternative to artificial erection in the diagnosis and treatment of penile anomalies.
Adult
;
Alprostadil
;
Blood Pressure
;
Child
;
Diagnosis
;
Dilatation
;
Female
;
Heart Rate
;
Hemorrhage
;
Humans
;
Hypospadias
;
Male
;
Penile Induration
;
Penis
;
Transplants
2.Ultrastructural Study on Basement Membrane Thickening of Iris Capillaries in Diabetic Patients.
Jun Seok TAE ; Jung Hyub OH ; Oh Woong KWON
Journal of the Korean Ophthalmological Society 1993;34(11):1148-1153
The early ultrastructural changes of basement membrane thickening and degeneration of the pericyte were noted in retinal capillaries in diabetic patients. However no early ultrastructural changes were reported in diabetic iris capillary. The authors studied the ultrastructural features of basement membrane of iris capillaries which were obtained during cataract surgery in five diabetic patients and compared with those obtained in five nondiabetic patients. The endothelium basal lamina, pericyte basal lamina and membrane-like pericyte matrix in didabetic iris capillaries were thicker than those in nondiabetic Iris capillaries. The thickening of pericyte basal lamina is more prominant than the endothelium basal lamina in diabetes. The duration of diabetes had no relationship to endothelium basal lamina but, showed statistically significant relationship to thickness of pericyte bascal lamina and pericyte matrix.
Basement Membrane*
;
Capillaries*
;
Cataract
;
Endothelium
;
Humans
;
Iris*
;
Pericytes
;
Retinaldehyde
3.The Effect of Ocular Massage in Cataract Extraction.
Dal Man KWON ; Jun Sup OH ; Jae Soo SUHK ; Bum Hi OH ; Pyo Sup HAN
Journal of the Korean Ophthalmological Society 1968;9(1):20-23
The authors have studied on the effect of digital pressure on eyeball under the surface anesthesia instead of other reducing agents of intraocular pressure and retrobulbar anesthesia in order to lower the intraocular pressure as a preoperative procedure of cataract extraction in 26 eyeballs of 24 patients and following results were obtained: 1. The authors had intraocular pressure lowered till averaging 10.8 mmHg (average 13.5 ~ 8.0 mmHg) of original pressure by ocular massage. 2. Massage on eyeball was thought to be a satisfactory preoperative procedure to perform cataract extractIon. 3. In operative complications, loss of vitreous and rupture of capsule were noticed 11.5% and 60% respectively. and it was thought to be caused by technical failure in surgeons. In view of this fact we could not find that the loss of vitreous was caused by intraocular pressure below 13.5 mmHg.
Anesthesia
;
Cataract Extraction*
;
Cataract*
;
Humans
;
Intraocular Pressure
;
Massage*
;
Preoperative Care
;
Reducing Agents
;
Rupture
4.A case of leiomyoma on urethrovaginal septum.
Kyung Jun OH ; Jae Young KIM ; Oh Hyun KWON ; Joo Kyun PARK ; Kyu Hwan KIM
Korean Journal of Urology 1991;32(1):160-161
Leiomyoma is rare. Most of patients present with urinary tract infection, hematuria, dyspareunia, or complaint of mass. A case of leiomyoma on urethrovaginal septum in a 36 years old female was presented. The presenting symptom was a protruding mass at the anterior vaginal wall The mass was removed surgically and confirmed as a leiomyoma pathologically.
Adult
;
Dyspareunia
;
Female
;
Hematuria
;
Humans
;
Leiomyoma*
;
Urinary Tract Infections
5.Rapid Detection of Mycobacteria usin Mycobacteria Growith Indicator tube(MGIT)and Ogawa Media.
Oh Gun KWON ; Hyun Mi CHO ; In Ho JANG ; Young UH ; Kap Jun YOON
Korean Journal of Clinical Microbiology 2000;3(2):116-120
BACKGROUND: As many as several weeks of incubation may be necessary for the recovery of mycobacteria when conventional culture media are used. Previous studies evaluating Mycobacteria Growth Indicator Tube (MGIT) as a rapid for the growth and detection of mycobacteria from clinical specimens have been reported. We compared MGIT with Ogawa media for the recovery of mycobacteria from clinical specimens. METHODS: Ninety nine clinical specimens received in the laboratory of Wonju Christian Hospital from June to September 199 were used for this study. The specimens from nonsterile body sites were digested, decontaminated, and concentrated, for culture and Ziehl-Neelsen stain, and specimen were inoculated onto MGIT tube and 3% Ogawa egg medium, and cultured for 8 weeks. RESULTS: Of the 38 specimens culture-positive for mycobacteria, 3 grew isolates in MGIT medium only, 8 grew isolates in Ogawa media only, and 27 grew isolates in both media. Mean (median, range) times to detection of mycobacteria were 13.7 (5.5, 2-48) days with MGIT and 19.6 (18, 13-37) days with Ogawa (P>0.05). The number recovered with MGIT plus Ogawa media was 24 (63.2%) within 14 days of receipt of specimen, and 31 (81.6%) within 21 days. The contamination rates were 31 % for MGIT and 1 % for Ogawa media. CONCLUSIONS: MGIT appears useful to quickly detect and identify mycobacteria from clinical specimens. However, because the number of culture-positive specimen in MGIT was not greater than those recovered with Ogawa media, MGIT should be used in combination with solid media to reduce turnaround times and increase the isolation rate.
Culture Media
;
Gangwon-do
;
Mycobacterium
;
Ovum
6.Rapid Detection of Mycobacteria usin Mycobacteria Growith Indicator tube(MGIT)and Ogawa Media.
Oh Gun KWON ; Hyun Mi CHO ; In Ho JANG ; Young UH ; Kap Jun YOON
Korean Journal of Clinical Microbiology 2000;3(2):116-120
BACKGROUND: As many as several weeks of incubation may be necessary for the recovery of mycobacteria when conventional culture media are used. Previous studies evaluating Mycobacteria Growth Indicator Tube (MGIT) as a rapid for the growth and detection of mycobacteria from clinical specimens have been reported. We compared MGIT with Ogawa media for the recovery of mycobacteria from clinical specimens. METHODS: Ninety nine clinical specimens received in the laboratory of Wonju Christian Hospital from June to September 199 were used for this study. The specimens from nonsterile body sites were digested, decontaminated, and concentrated, for culture and Ziehl-Neelsen stain, and specimen were inoculated onto MGIT tube and 3% Ogawa egg medium, and cultured for 8 weeks. RESULTS: Of the 38 specimens culture-positive for mycobacteria, 3 grew isolates in MGIT medium only, 8 grew isolates in Ogawa media only, and 27 grew isolates in both media. Mean (median, range) times to detection of mycobacteria were 13.7 (5.5, 2-48) days with MGIT and 19.6 (18, 13-37) days with Ogawa (P>0.05). The number recovered with MGIT plus Ogawa media was 24 (63.2%) within 14 days of receipt of specimen, and 31 (81.6%) within 21 days. The contamination rates were 31 % for MGIT and 1 % for Ogawa media. CONCLUSIONS: MGIT appears useful to quickly detect and identify mycobacteria from clinical specimens. However, because the number of culture-positive specimen in MGIT was not greater than those recovered with Ogawa media, MGIT should be used in combination with solid media to reduce turnaround times and increase the isolation rate.
Culture Media
;
Gangwon-do
;
Mycobacterium
;
Ovum
7.A Case of Pigmented Fungiform Papillae of the Tongue.
Oh Chan KWON ; Dong Won LEE ; Jun Young LEE ; Baik Kee CHO
Korean Journal of Dermatology 1998;36(6):1134-1136
Pigmented fungiform papillae of the tongue is a rare disorder in Korea. It is characterized clinically by pigmentation confined to the fungiform papillae and histopathologically by the presence of melanophages in the upper dermis. We report a case of pigmented fungiform papillae of the tongue in a 21-year-old woman who had brown to violaceous dots on the fungiform papillae and pigmented patches on the right lateral dorsum of the tongue. Histological findings showed increased melanophages in the upper dermis.
Dermis
;
Female
;
Humans
;
Korea
;
Pigmentation
;
Tongue*
;
Young Adult
8.Optic Disc Hamartoma Combined with Optic Neuritis.
Jin Hyung KIM ; Hyoung Jun KOH ; Oh Woong KWON
Journal of the Korean Ophthalmological Society 2001;42(6):911-915
PURPOSE: Optic disc harmatoma is usually seen in tuberous sclerosis patients, but, it may be seen in otherwise normal people. Visual acuity is usually not affected by this lesion. METHODS: We experienced a 40-year-old woman with optic disc hamartoma who presented with acute visual defect. With oral triamcinolone 48mg/day, her visions recovered to normal in 2 weeks. RESULTS: Her age, symptom, and course of disease supported the diagnosis of optic neuritis. CONCLUSION: We report this patient as a case of optic disc hamartoma combined with optic neuritis.
Adult
;
Diagnosis
;
Female
;
Hamartoma*
;
Humans
;
Optic Neuritis*
;
Triamcinolone
;
Tuberous Sclerosis
;
Visual Acuity
9.Polypoid Cystitis Mimicking Bladder Tumor: A Case Report.
Journal of the Korean Radiological Society 2002;46(1):63-66
Polypoid cystitis without a history of catheterization is rare. We report a case in which the condition occurred in a 16-year-old girl complaining of dysuria, urgency, frequency, and a residual urine sensation. Cystography revealed a large intravesical filling defect with bladder distension, while sonography and CT demonstrated a large, inhomogeneously enhancing solid mass in the urinary bladder.
Adolescent
;
Catheterization
;
Catheters
;
Cystitis*
;
Dysuria
;
Female
;
Humans
;
Sensation
;
Urinary Bladder Neoplasms*
;
Urinary Bladder*
10.Treatment of Liver Abscess.
Chang Oh YOO ; Byung Jun SO ; Kwon Mook CHAE
Korean Journal of Hepato-Biliary-Pancreatic Surgery 1998;2(1):61-71
BACKGROUND: To evaluate the changing pattern of liver abscess treatment, we did a retrospective analysis of 80 patients with liver abscess, treated surgically and medically at the Department of Surgery and Internal Medicine, Wonkwang University Hospital from January 1985 to December, 1995. RESULTS: Among 80cases of liver abscess, 59 cases(76%) were pyogenic abscess and 21 cases(24%) were amebic abscess. The liver abscess was more commonly located in the right lobe. In the 59cases of pyogenic liver abscess, etiologic factors were biliary stones with cholangitis(19 cases), cholecystitis(6 cases), hepatobiliary cancer(4 cases), diabetes mellitus(3 cases). All 21 cases of amebic abscess were treated with percutaneous catheter drainage and metronidazole administration; 20 cases were treated successfully and 1 case died of sepsis. Among the 59 cases of pyogenic liver abscess, 38 cases were treated with percutaneous catheter drainage; 30 cases were successful, but 8 cases were not. Operations were performed in 21 cases because of underlying intraabdominal conditions requiring surgical correction( 19cases) and panperitonitis due to rupture of liver abscess(2cases). CONCLUSION: In the treatment of amebic abscss, percutaneous catheter drainage and metanidazole adminstration should be considered first. Percutaneous catheter drainage and antibiotic treatment tend to increase more than surgical treatment in the pyogenic liver abscess therapy. The liver abscess is no more surgical indication, unless it is associated with underlying intraabdominal conditions requiring surgical correction and panperitonitis due to rupture of liver abscess.
Abscess
;
Amebiasis
;
Catheters
;
Drainage
;
Humans
;
Internal Medicine
;
Liver Abscess*
;
Liver Abscess, Amebic
;
Liver Abscess, Pyogenic
;
Liver*
;
Metronidazole
;
Retrospective Studies
;
Rupture
;
Sepsis