The completion of the rough draft of the human genome is a remarkable achievement. It provides the overall structures of huge DNA molecules that constitute the genome and an outline of the information needed to create a human being This paper reviewed new ideas, projects, and scientific advances made by the Human Genome Project. We also discussed the future of medicine and biomedical research in postgenomic era.
DNA ; Genome ; Genome, Human* ; Genomics ; Human Genome Project* ; Humans ; Humans* ; Proteome ; Proteomics

No abstract available.
Enterococcus*

No abstract available.
Enterococcus*

Nursing the aged is yet a familiar system in Korea. However, it is a social system in urgent need that requires series of preliminary arrangements to cope with the aging society. In addition, a full-fledged preparedness is imperative, lest the nursing system should follow precedent failures of the National Medical Insurance System and the separation of dispensary from medical practice. The concept of nursing the aged exceeds the simple care (so called 'Subal') of inconveniences caused by the process of aging. One should keep in mind that 'nursing the aged' outcomes from the illness as well as the aftereffect thereof. These physical and mental inconveniences should be overcome by means of medical treatments and care that are oriented to proper physical conditions. All sectors of specialties relevant to elderly nursing care should be systematically working together, so as to set up a sound master plan for nursing the aged. Both medical and para-medical human resources shall be secured and, they must be ready to work in good harmony. Medical approaches as to the home-cares and, construction of the infrastructures relevant thereto shall be properly taken place during the pre-testing period.
Aged* ; Aging ; Home Care Services ; Humans ; Insurance ; Korea ; Long-Term Care* ; Nursing ; Nursing Care

Endoscopic ACL reconstruction using bone-patellar tendon-bone has been considered the gold standard in the field of reconstructive ACL surgery. Technically, graft must be placed at isometric point. But it is difficult to evaluate the placement of graft postoperatively. The purpose of this study is to determine the radiological ideal position of graft by comparing postoperative results with the graft placement. Seventy cases of endoscopic ACL reconstruction were reviewed and classified according to the femoral and tibial graft position on radiologic imaging. The femoral graft position was classified in relation to angle of graft on anterior position view and distance from posterior margin of graft to the inner surface of posterior cortex on lateral view. The tibial graft position was classified in relation to intercondylar eminence on anterior posterior view and lateral view. Knee score (modified Marshall, Lysholum), manual anterior instability test (Lachman test, Pivot shift test) and arthrometer measurement were checked to evaluate postoperative results in each case. The results of this study implicate that knee joint in which femoral graft was oriented at direction of 11 o clock centring around 68 degree respect to tibial joint and placed within 3mm from posterior cortex showed higher knee score and lesser laxity. In cases of tibial side, the graft oriented to intercondylar eminence (AP view) and placed anterior to intercondylar eminence (lateral view) showed higher knee score and lesser laxity.
Joints ; Knee ; Knee Joint ; Patellar Ligament* ; Transplants

No abstract available.
Fractures, Open*

Fifteen stress urinary incontinence patients were treated using the modified endoscopic suspension of the bladder neck that eliminates all incisions during the period from January 1990 to December 1990. The average operation time was 26 minutes and the mean days of urethral Foley catheter removal were 3.9 days operation. Two point three days were required to restore the normal voiding pattern. Of 15 patients treated. 1 failure occurred, for an overall success rate of 93%. There had been no significant complications. Therefore, no-incision pubovaginal suspension was simple and effective means treating stress urinary incontinence.
Catheters ; Humans ; Neck ; Urinary Bladder ; Urinary Incontinence*

Spontaneous infrarenal abdominal aortic dissection (SIAAD) is a rare entity with various clinical presentations. We recently encountered the even rarer condition of a female patient suffering from chronic SIAAD with multiple intimal flaps and prominent lumbar artery collaterals; this all caused stenotic changes of the infrarenal abdominal aorta and produced progressive lower extremity pain and claudication in both her legs. This patient's condition was successfully managed by primary stent placement followed by balloon angioplasty.
Angioplasty, Balloon ; Aorta, Abdominal ; Arteries ; Female ; Humans ; Leg ; Lower Extremity ; Stents*

Pustulotic arthro-osteitis is a rheumatic syndrome of unknovn cause, characterised by an inflammatory osteitis of the sternocostoclavicular region and pustuosis palmaris et plantaris. Although many ases of the disease have been reported in Japan, it, has not been reported in Korea so far. Three cases of pustulosis palmaris et plantaris associated i rith sternocostoclavicular hyperostosis or pustulotic arthro-osteitis are presented.
Hyperostosis, Sternocostoclavicular* ; Japan ; Korea ; Osteitis ; Psoriasis*

Homozygous Protein C deficiency is a rare genetic disease with catastrophic and fatal purpura fulminans like or thrombotic complication occurring during the neonatal period. Purpura fulminans is characterized by microvascular thrombosis in the dermis followed by perivascular hemorrhage, necrosis, and minimal inflammation. Laboratory findings are consistent with disseminated intravascular coagulopathy: We report a case of purpura fulminans in a neonate with the findings of disseminated intravascular coagulopathy and an undetectable level of protein C activity, whose parents proved to be heterozygous protein C deficiency.
Dermis ; Hemorrhage ; Humans ; Infant, Newborn ; Inflammation ; Necrosis ; Parents ; Protein C Deficiency* ; Protein C* ; Purpura Fulminans* ; Purpura* ; Thrombosis