1.In vitro storage lesions of filterd RBC after irradiation.
Oh Hun KWON ; Chung Hyun NAHM ; Hyun Ok KIM ; Chang Ok SUH ; Gwi Eon KIM
Korean Journal of Hematology 1993;28(1):135-141
No abstract available.
3.Categorization of Vascular Lesions and Selection of Treatment Modalities Using Color Doppler Ultrasound.
Oh Eon KWON ; Jong Young OH ; Chae Wook LEE ; Ki Ho KIM
Korean Journal of Dermatology 2005;43(11):1488-1496
BACKGROUND: Vascular lesions can be diagnosed by biopsy, simple x-ray, ultrasound, CT, MRI, venography and MR angiography. These diagnostic tools can identify the detailed structure and abnormalities in the peri-lesional area of vascular lesions. Color Doppler ultrasound (CDU) can demonstrate the hemodynamic features, distribution of veins and arteries, shunts and structures of vascular lesions. Authors have tried to categorize vascular lesions with CDU and also applied this to the selection of treatment methods. MATERIALS AND METHODS: Forty-seven vascular lesions were evaluated by means of CDU. All patients underwent a complete clinical evaluation as well as peak systolic velocity (PSV), peak diastolic velocity (PDV), resistive index (RI) of feeding arteries. In particular, we evaluated the hemodynamic features and structures of vascular lesions. We categorized the vascular lesions and then treated them with systemic steroid, compression, SPTL1 Dye laser, steroid intralesional injection and sclerotherapy. We evaluated the clinical improvement and objective effects of treatments by CDU. RESULTS: There were 37 hemangiomas and 10 vascular malformations. Vascular lesions were classified by the hemodynamic features and structures: category Ia (infantile hemangioma, regressed infantile hemangioma), Ib (RICH), Ic (deep hemangioma, mixed hemangioma), II (arteriovenous malformation), III (venous malformation, verrucous hemangioma). The clinical improvement after treatment was associated with the decrease of PSV and RI values. The clinical improvement above 50% resolution of the lesion showed 70.9% in category Ia, 50% in Ib, 66.6% in Ic, 83.3% in II and 50% in III. CONCLUSIONS: The analysis of hemodynamic feature and structures by CDU can be helpful in the study of vascular lesions. These processes suggest CDU be a useful modality in differential diagnosis of vascular lesions and a more advantageous tool in the decision of treatment policy than the conventional modalities. And it is also useful for the evaluation of treatment effects.
Angiography
;
Arteries
;
Biopsy
;
Diagnosis, Differential
;
Hemangioma
;
Hemodynamics
;
Humans
;
Injections, Intralesional
;
Lasers, Dye
;
Magnetic Resonance Imaging
;
Phlebography
;
Sclerotherapy
;
Ultrasonography*
;
Vascular Malformations
;
Veins
4.A Case of Calcifying Aponeurotic Fibroma with Gait Disturbance.
Oh Eon KWON ; Bon Seok KU ; Dae Cheol KIM ; Chae Wook LEE ; Ki Ho KIM
Korean Journal of Dermatology 2006;44(1):71-74
Calvus, callus, plantar warts and piezogenic papules are well known to cause discomfort and disturbance of gait in ordinary physical and sports activities. Furthermore, calcifying aponeurotic fibroma, whose mass slowly grows on the palms and soles of children and young adults, leads to pain, disturbance of gait, and even to skeletal deformities. A 22-year-old woman noticed an elevated subcutaneous mass on the left plantar surface of her big toe, which was accompanied with pain, tenderness and gait disturbance. The histologic findings showed an ill-circumscribed fibroblastic proliferation with foci of calcification and chondroid differentiation. After total excision of the mass, the patient became free of the above symptoms and the lesion did not recur for 9 months.
Bony Callus
;
Child
;
Congenital Abnormalities
;
Female
;
Fibroblasts
;
Fibroma*
;
Gait*
;
Humans
;
Sports
;
Toes
;
Warts
;
Young Adult
5.A Case of SAPHO Syndrome in a Palmoplantar Pustulosis Patient.
Oh Eon KWON ; Hong Seok KIM ; Seung Joo SIM ; Ki Hoon SONG ; Ki Ho KIM
Korean Journal of Dermatology 2005;43(2):239-243
SAPHO syndrome is characterized by sternocostoclavicular osteoarthritis and hyperostosis in the anterior chest wall, and skin changes such as palmoplantar pustulosis and acne. Despite the higher frequency of psoriasis in this syndrome, its inclusion in the psoriatic arthropathy spectrum is not yet clearly established to date. According to a familial series of the SAPHO syndrome, both sacroiliac and sternoclavicular joints could be involved. We report a case of SAPHO Syndrome in a palmoplantar pustulosis patient who had on associated osteoarticular manifestation. A 47-year-old woman had been treated for palmoplantar pustulosis for 15 months. Pain and tenderness then developed abruptly on the chest and neck, and multiple erythematous papules and pustules broke our over the whole body. Laboratory tests were negative for serum RA factor and ANA, and positive for HLA-B27. An X-ray showed a hyperostosis, osteolytic and osteosclerotic lesions in the costo-sterno-clavicular junction. 99mTc isotope scan showed the typical "Bull's head sign" in the anterior chest wall due to increased uptake in the manubrium and both sternoclavicular joints.
Acne Vulgaris
;
Acquired Hyperostosis Syndrome*
;
Arthritis, Psoriatic
;
Female
;
Head
;
HLA-B27 Antigen
;
Humans
;
Hyperostosis
;
Manubrium
;
Middle Aged
;
Neck
;
Osteoarthritis
;
Psoriasis
;
Skin
;
Sternoclavicular Joint
;
Thoracic Wall
;
Thorax
6.A Clinical Analysis of the Risk Factors of Varicose Veins in Korean.
Ki Hoon SONG ; Oh Eon KWON ; Hong Seok KIM ; Ki Ho KIM
Korean Journal of Dermatology 2005;43(6):762-768
PURPOSE: Varicose veins occur commonly in the general population, however the etiology is not well established. Varicosities are frequently associated with a reflux of blood in the leg veins due to valvular incompetence. Our aim was to determine which risk factors are related to reflux in the general population, and thus could be implicated in the etiology of varicose veins. METHOD: One hundred and eighty nine patients were assessed and their clinical records from March 2001 to June 2004 were reviewed. They were all diagnosed as having primary varicose veins of the lower extremities using duplex ultrasonography. We analyzed the sex, age, symptoms, signs, duration, location and CEAP classification. Patients also completed a self-administered questionnaire, asking about their objectives of the visit, cigarette consumption, familial history, previous pregnancies, use of drugs such as oral contraceptives, hormones, and anticoagulant agents, and other associated diseases. We carried out duplex scans to measure the reflux in venous segments in each leg. RESULTS: The mean age was 46.0 years, and there were 3.3 times more females than males. The most common CEAP classification was C2sEpAsPr, followed by C2aEpAsPr and C1sEpAsPr. Venous reflux was significantly associated with females (p=0.0067), duration (p=0.0027), pregnancy (p=0.0034), smoking (p=0.0360), family history of mother (p=0.0082) and brother (p=0.0360), heaviness (p=0.0120) and stasis dermatitis or ulcer (p=0.0219). CONCLUSION: This study identified relatively strong and consistent risk factors of venous reflux that are associated with females, pregnancy, smoking, duration, family history of the mother or brother, heaviness, and stasis dermatitis or ulcers.
Anticoagulants
;
Classification
;
Contraceptives, Oral
;
Dermatitis
;
Female
;
Humans
;
Leg
;
Lower Extremity
;
Male
;
Mothers
;
Pregnancy
;
Risk Factors*
;
Siblings
;
Smoke
;
Smoking
;
Tobacco Products
;
Ulcer
;
Ultrasonography
;
Varicose Veins*
;
Veins
;
Surveys and Questionnaires
7.Angiomatoid Spitz Nevus.
Oh Eon KWON ; Bon Seok KU ; Yeong Kyu LEE ; Young Hun KIM ; Ki Ho KIM
Annals of Dermatology 2008;20(1):14-17
Spitz nevus is a variant of melanocytic nevus which is histopathologically defined as large spindle and/or epithelioid cells. Angiomatoid Spitz nevus is a rare histologic variant of desmoplastic Spitz nevus characterized by prominent vasculature. We present a case of angiomatoid Spitz nevus, celluar type, that has not been reported before. We provide another example to show the remarkable diversity of Spitz nevus.
Epithelioid Cells
;
Nevus, Epithelioid and Spindle Cell
;
Nevus, Pigmented
8.Multiple Cutaneous Edema and Infiltration of Signet-ring Cells in the Lymphatics as an Initial Manifestation of Metastatic Gastric Adenocarcinoma.
Oh Eon KWON ; Bon Seok KU ; Dae Cheol KIM ; Chae Wook LEE ; Ki Ho KIM
Korean Journal of Dermatology 2006;44(5):601-604
Signet-ring cells are cells in which the nucleus is crescentically compressed with a cellular border, so that the cell looks like a signet-ring. Many cutaneous signet-ring cell neoplasms originate from the stomach, lung and breast, and these appear to be the most common sites of origin. In skin, the appearance of signet-ring cells within a neoplasm can indicate metastatic adenocarcinoma of the stomach, lung and breast. Thus, the primary origin and other metastatic sites should be evaluated. A 44-year-old man presented with a six month history of cutaneous swelling on the left axillary and left supraclavicular area. Histopathologic findings of the axillary lesion showed signet-ring cells in the lymphatics. These clustered cells were PAS-positive, diastase-resistant, and stained with colloidal iron and CEA. During the work-up study to find the primary origin, we discovered advanced gastric cancer and multiple lymph node metastases.
Adenocarcinoma*
;
Adult
;
Breast
;
Colloids
;
Edema*
;
Humans
;
Iron
;
Lung
;
Lymph Nodes
;
Neoplasm Metastasis
;
Skin
;
Stomach
;
Stomach Neoplasms
9.A Case of Muticentric Reticulohistiocytosis Misdiagnosed As Rheumatoid Arthritis.
Oh Eon KWON ; Ki Hoon SONG ; Hong Seok KIM ; Dae Cheol KIM ; Ki Ho KIM
Korean Journal of Dermatology 2005;43(1):81-85
Multicentric reticulohistiocytosis (MRH) is a rare multisystemic granulomatous disease of unknown cause, characterized by severe debilitating polyarthritis and papular to nodular mucocutaneous lesions. This disease usually manifests as a progressive, destructive polyarthritis with mucocutaneous eruptions consisting of erythematous to brownish-colored papules and nodules. MRH is important, not only because of its disfiguring and disabling manifestations and systemic involvements, but also due to its association with internal malignancy. The histological features of skin and synovial lesions are infiltration of multinucleated giant cells, and histiocytes which contain abundant eosinophilic cytoplasm and have a ground glass appearance. Without the accompanying skin nodules, the patients can be misdiagnosed as having rheumatoid arthritis or psoriatic arthritis, and this inaccurate diagnosis will affect treatment. We report a case of MRH which was misdiagnosed as rheumatoid arthritis.
Arthritis
;
Arthritis, Psoriatic
;
Arthritis, Rheumatoid*
;
Cytoplasm
;
Diagnosis
;
Eosinophils
;
Giant Cells
;
Glass
;
Histiocytes
;
Humans
;
Skin
10.A Case of Lentigo Maligna Melanoma Treated with Mohs Micrographic Surgery.
Bon Seok KU ; Oh Eon KWON ; Dae Cheol KIM ; Keun Cheol LEE ; Chae Wook LEE ; Ki Ho KIM
Korean Journal of Dermatology 2006;44(4):457-461
Lentigo maligna melanoma and lentigo maligna are typically located on photo-exposed sites such as the head and neck, with the cheek being the most common site. Since lentigo maligna melanoma and lentigo maligna are found predominantly on such cosmetically-sensitive areas, it is critical to determine the exact histologic margin for maximal sparing of tissue and complete extirpation of the tumor. Since Mohs micrographic surgery has been recommended for tumors on cosmetically-sensitive locations where the tumor margin is indistinct, it appears to be a reasonable treatment modality for this type of tumor. We describe a case of lentigo maligna melanoma on the cheek, which was resected with Mohs micrographic surgery.
Cheek
;
Head
;
Hutchinson's Melanotic Freckle*
;
Lentigo*
;
Melanoma*
;
Mohs Surgery*
;
Neck