PURPOSE: The Swedish Interactive Thresholding Algorithm (SITA) strategies is a new diagnostic tool of Humphrey automatic perimetry and has been reported to reduce testing time without loss of useful diagnostic information. To test the usefulness of this new diagnostic method, we compared the SITA and full threshold diagnostic method, which had been used previously. METHODS: Forty six patients (46 eyes) who were followed up for glucoma or ocular hypertension were in this study. Autoperimetry was performed using both SITA and full threshold strategies. RESULTS: The SITA showed shorter testing time (7.74+/-1.25 min) than the full threshold (14.4+2.43 min). There were significant differences between the full threshold MD (-8.06+8.11 dB) and SITA MD (-7.45 +/-8.32 dB), as well as full threshold PSD (4.47+/-2.50 dB) and SITA PSD (3.67+/-2.56 dB), when compared with data of greater than -12 dB MD respectively(p<0.05). Two cases showed changed diagnosis in GHT. CONCLUSIONS: SITA is a good test method with short test time. However, changing from full threshold to the SITA method should be reconsidered due to variation in the amount of field defect depending on the damage progression and the possibility of changes in diagnosis.
Diagnosis ; Glaucoma* ; Humans ; Ocular Hypertension ; Visual Field Tests

PURPOSE: To evaluate the pressure-lowering effects of selective trabeculoplasty versus these of Argon laser trabeculoplasty. METHODS: Fifteen eyes of 15 patients with primary open-angle glaucoma and ocular hypertension, all with IOPs over 30 mm Hg received SLT and 30 eyes of 30 patients with the same diagnosis were treated with ALT. Patients were evaluated after laser treatments at 1 hour, 1 day, 1 week, 1 month, and 3 months using slit lamp examinations and Goldmann applanation tonometry. RESULTS: At 3 months postoperative, the SLT group had a mean IOP of 16.9+/-4.2 mmHg with a mean reduction of 31.2+/-20.1%, while the ALT group had a mean IOP of 17.9+/-5.4 mmHg with a mean reduction of 26.3+/-23.3%. CONCLUSIONS: Selective trabeculoplasty and Argon laser trabeculoplasty are equally effective statistically in lowering IOP over a 3-month period (p=0.47). SLT has been shown to be safe and effective in lowering IOP.
Argon* ; Diagnosis ; Glaucoma, Open-Angle* ; Humans ; Manometry ; Ocular Hypertension ; Trabeculectomy*

As accommodation and repeated tonometry were known to change the level of intraocular pressure, sometimes they may give a misleading indication for the diagnosis and management of early glaucoma, ocular hypertension and low tension glaucoma. The object of this study was to investigate the effects of accommodation and repeated tonometry on intraocular pressure in Korean adults. Repeated tonometry was performed on 120 normal Korean eyes with visual acuity of 20/20 or more under controlled condition of accommodation and relaxation using Goldmann applanation tonometry and Schiotz tonometry. The results were as follows: 1. In repeated Goldmann applanation tonometry, a statistically significant reduction in mean intraocular pressure was produced during accommodation but not during relaxation. The maximum reduction of 3.25mmHg was produced during four minutes of accommodation and significant reduction of 2.01 mmHg was shown in first one minute of accommodation. 2. In repeated Schiotz tonometry, a statistically significant reduction in mean intraocular pressure was produced during accommodation but not during relaxation. The maximum reduction of 3.71mmHg was produced during four minutes of accommodation and significant reduction of 2.39 mmHg was shown in first one minute of accommodation.
Adult* ; Diagnosis ; Glaucoma ; Humans ; Intraocular Pressure ; Low Tension Glaucoma ; Manometry* ; Ocular Hypertension ; Relaxation ; Visual Acuity

PURPOSE: To evaluate the clinical manifestations and the factors associated with prognosis of the traumatic cyclodialysis patients who underwent direct cyclopexy. METHODS: The authors retrospectively analyzed the data of 23 eyes of 22 patients who underwent consecutive direct cyclopexy for the hypotonous cyclodialysis between 1997 and 2002 at the authors' institution. Perioperative A-scan and ultrabiomicroscopy were performed to evalaute correlation between the parameters and postoperative visual prognosis. RESULTS: Postoperatively, the mean increase of intraocular pressure was 11.1mmHg and the mean improvement of visual acuity was four lines of Han's Korean visual acuity chart. As the preoperative hypotony period was shorter, postoperative visual prognosis was better (p<0.05). Anterior chamber depth (p<0.0001), axial length (p<0.01), spherical equivalent (p<0.05), and intraocular pressure (p<0.0001) were increased, whereas lens thickness (p<0.0001) was decreased postoperatively. Transient postoperative ocular hypertension was controlled by adequate medication, and the patients' intraocular pressure were controlled below 20 mmHg without medications at the average of 19 days after the cyclopexy. Post-operative visual acuity was not significantly correlated with pre-operative intraocular pressure, pre-operative visual acuity, age, or sex. Preoperative extent of cyclodialysis was not significantly correlated with visual prognosis, postoperative development of cataract, intraocular pressure, or the cause of trauma. CONCLUSIONS: Direct cyclopexy is one of a successful method for the treatment of the hypotonous cyclodialysis cleft, and the early diagnosis and treatment are thought to be necessary for the improvement of visual prognosis.
Anterior Chamber ; Cataract ; Early Diagnosis ; Humans ; Intraocular Pressure ; Ocular Hypertension ; Prognosis ; Retrospective Studies ; Visual Acuity

We evaluated one of the new non-contact tonometers, the Pulsair non-contact tonometer, to assess its accuracy and reliability. Measurements on 101 eyes were used to assess its accuracy against Goldmann tonometry measurements, and another 24 eyes were used to assess its reliability (reproducibility). The results showed the instrument to be highly accurate and reliable in measurement.
Evaluation Studies as Topic ; Female ; Humans ; Intraocular Pressure ; Male ; Ocular Hypertension/diagnosis ; Predictive Value of Tests ; Regression Analysis ; Reproducibility of Results ; Tonometry, Ocular/*instrumentation ; Vision Screening/*methods

PURPOSE: To determine the effect of central corneal thickness (CCT) on the measurement of intraocular pressure (IOP) and diagnosis of glaucoma on the resultant reclassification of patients as having primary open-angle glaucoma (POAG), normal tension glaucoma (NTG), or ocular hypertension (OHT). METHODS: Intraocular pressure (Goldmann applanation tonometry) and visual field test (Humphrey 24-2) were measured in 22 eyes of 23 patients with OHT, 20 eyes of 20 patients with POAG, 31 eyes of 31 patients with NTG, 27 eyes of 27 control subjects. CCT was measured and used to obtain a corrected value for the IOP and to reclassify the type of glaucoma. RESULTS: There was no significant difference in CCT between controls and patients with POAG, but the CCT in the group with NTG was significantly lower than that in the control group (p=0.012), and the CCT in the group with OHT was significantly higher than in controls (p=0.002). Correcting IOP for corneal thickness, 22.58% of patients with NTG could be reclassified as having POAG, and 56.52% of the patients with OHT as normal. CONCLUSIONS: Underestimation of the IOP in patients with POAG who have thin cornea may lead to a misdiagnosis of NTG, while overestimation of the IOP in normal subjects who have thick cornea may lead to a misdiagnosis of OHT. We suggest that CCT must be considered in diagnosis of glaucoma.
Cornea ; Diagnosis* ; Diagnostic Errors ; Glaucoma* ; Glaucoma, Open-Angle ; Humans ; Intraocular Pressure ; Low Tension Glaucoma ; Ocular Hypertension ; Visual Field Tests

The human pattern reversal retinal potential(PRRP) is a bioelectrical response that reflects neural activity generated in the proximal retina. Visual diseases which affect the retinal ganglion cells and the optic nerve often produce signifjcant reductions in the amplitude of the PRRP. PRRP amplitude reductions are freguently obseved in the patients with primary open angle glaucoma. This study was designed to determine whether patients with ocular hypertension whieh are at risk of developing glaucoma also exhibit PRRP amplitude reductions. 1. As compared to the control group the glaucoma patients showed decreased P1-N2 amplitude and a significant delay of Visual evoked potential(VEP) latency. The retinocortical time was delayed(72%) and PRRP P1-N2 amplitude was decreased in 30 percents of the ocular hypertensive patients. 2. In the glaucoma and ocular hypertension, VEP P1 latency has more diagnoic value than PRRP P1 latency. 3. VEP and PRRP show more diagnostic values and these tests are essential for early diagnosis in the glaucoma.
Early Diagnosis ; Evoked Potentials, Visual ; Glaucoma ; Glaucoma, Open-Angle ; Humans ; Ocular Hypertension* ; Optic Nerve ; Retina ; Retinal Ganglion Cells ; Retinaldehyde*

Adenosine deaminase(ADA)has been used for the diagnosis of localized tuberculosis.The titer of ADA was measured from the ocular fluid of the patients who had undergone vitreoretinal surgery due to non-tuberculous vitreoretinal disease. Forty five patients were included and twenty patients were male. Mean age was 51.9 years. Four patients had diabetes mellitus and two had essential hypertension. The most frequent cause of vitreoretinal surgery was proliferative vitreoretinopathy(12 eyes). For the analysis of ADA titer, vitreous fluid(group I)was aspirated in 36 patients undergoing pars plana vitrectomy and subretinal fluid(group II)in 9 patients undergoing scleral encircling. Mean titer of ADA was 9.01+/-15.69 IU/L, and there was no significant difference on the statistics between group I(6.06+/-13.75 IU/L)and group II(20.83+/-18.17 IU/L). All 45 eyes showed negative reaction to polymerase chain againt tuberculosis, and 25 of 29 patients had positive reaction to tuberculin skin test. There was no statistically significant relationship between ADA titer and tuberculin skin test. This result suggests that ADA may be used for the diagnosis of posterior ocular tuberculosis, since the normal concentration in the posterior ocular fluid was compatible with the one in other body fluids where it has been used for the diagnosis of localized tuberculosis.
Adenosine Deaminase* ; Adenosine* ; Body Fluids ; Diabetes Mellitus ; Diagnosis ; Humans ; Hypertension ; Male ; Skin Tests ; Tuberculin ; Tuberculosis ; Tuberculosis, Ocular ; Vitrectomy ; Vitreoretinal Surgery

No abstract available.
Chronic Disease ; Cryopyrin-Associated Periodic Syndromes/*complications/diagnosis ; Gonioscopy ; Humans ; *Intraocular Pressure ; Male ; Microscopy, Acoustic ; Middle Aged ; Ocular Hypertension/diagnosis/*etiology/physiopathology ; Rare Diseases

We have investigated the potential usefulness of stereoscopic viewing of optic disc photographs in marking the disc margin in computerized analysis with the Rodenstock Analyzer in 48 eyes of 26 patients with ocular hypertension or primary open-angle glaucoma. Marking of the disc margin without Method 1) and with the aid of stereoscopic viewing of disc photographs (Method 2) three consecutive times by one observer at the same sitting, and three subsequent topographic analyses of each method were done on each 48 eyes. The mean intraphotographic variabilities of such optic disc parameters as rim area, and cup volume with Method 2 were significantly less than those with Method 1 overall and in 16 eyes (33%) with poor video images having an ill-defined disc margin (p less than 0.05 for each), but not in 32 eyes (67%) with clear video images having a well-defined disc margin. Furthermore, the mean paired differences of rim area, disc area and cup volume between the two methods (Method 1 minus Method 2) were also statistically significant overall and in eyes with poor video images (p less than 0.05 for each).
Adult ; Aged ; Female ; Glaucoma, Open-Angle/pathology ; Human ; *Image Interpretation, Computer-Assisted ; Male ; Middle Age ; Ocular Hypertension/diagnosis ; Optic Disk/*anatomy & histology/pathology ; Photography