2.Correlation Between Frequency Doubling Technology Perimetry and Scanning Laser Polarimetry in Glaucoma Suspects and Glaucomatous Eyes.
Su Hyun KIM ; Hunei HONG ; Hee Jo KOO ; Sung jae YANG ; Hungwon TCHAH ; Michael S KOOK
Korean Journal of Ophthalmology 2004;18(2):89-99
The aim of this study was to determine the relationship between the frequency doubling technology (FDT) screening algorithm and parapapillary retinal nerve fiber layer (RNFL) thickness in the eyes of glaucoma suspects and patients with open angle glaucoma. FDT C20-1 screening program and a scanning laser polarimetry (SLP) system (GDx-NFA) was used to assess 53 glaucomatous eyes, 53 glaucoma suspects and 36 normal control eyes. In glaucomatous eyes, there were correlations between the FDT the screening algorithm and RNFL retardation values in several polarimetric indices, most significantly "inferior thickness" (r = -0.321, P = 0.029). In the eyes of glaucoma suspects, however, we observed no correlation between the FDT results and RNFL retardation values (r = 0.080, P > 0.05, "inferior thickness"). In glaucomatous eyes, the abnormal scores obtained with FDT screening program correlated negatively with RNFL retardation values, as measured by SLP. Despite poor correlation between the FDT abnormal score and RNFL retardation value in glaucoma suspects, detection of abnormality using the FDT screening protocol may aid in the assessment of early glaucomatous structural damage.
Comparative Study
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Glaucoma, Open-Angle/*diagnosis/physiopathology
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Humans
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Intraocular Pressure
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Lasers/diagnostic use
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Microscopy, Confocal
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Middle Aged
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Nerve Fibers/*pathology
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Ocular Hypertension/diagnosis/physiopathology
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Optic Nerve/*pathology
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Perimetry/*methods
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Retinal Ganglion Cells/*pathology
3.Congenital Aniridia: Long-term Clinical Course, Visual Outcome, and Prognostic Factors.
Ji Woong CHANG ; Jeong Hun KIM ; Seong Joon KIM ; Young Suk YU
Korean Journal of Ophthalmology 2014;28(6):479-485
PURPOSE: To describe the clinical course of congenital aniridia and to evaluate prognostic factors for visual outcome after long-term follow-up. METHODS: The medical records of 120 eyes from 60 patients with congenital aniridia were retrospectively reviewed. The prevalence and clinical course of ophthalmic characteristics, systemic disease, refractive errors, and visual acuity were assessed. Prognostic factors for final visual outcomes were analyzed. RESULTS: Aniridic keratopathy developed in 82 (69%) of 119 eyes. Macular hypoplasia was observed in 70 eyes of 35 patients (91%). Cataract was observed in 63 of 120 eyes (53%). Nystagmus was present in 41 patients (68% of 60 patients) at the initial visit but decreased in five patients (8% of 60 patients). Ocular hypertension was detected in 19 eyes (20% of 93 eyes), six (32% of 19 eyes) of which developed secondarily after cataract surgery. The mean changes in spherical equivalent and astigmatism during the follow-up period were -1.10 and 1.53 diopter, respectively. The mean final visual acuity was 1.028 logarithm of minimal angle of resolution. Nystagmus and ocular hypertension were identified as prognostic factors for poor visual outcome. CONCLUSIONS: Identification of nystagmus and ocular hypertension was important to predict final visual outcome. Based on the high rate of secondary ocular hypertension after cataract surgery, careful management is needed.
Adolescent
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Adult
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Aniridia/*diagnosis/physiopathology
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Cataract/diagnosis
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Child
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Child, Preschool
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Corneal Diseases/diagnosis
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Eye Abnormalities/diagnosis
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Eye Diseases/*diagnosis/physiopathology
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Follow-Up Studies
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Humans
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Infant
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Infant, Newborn
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Nystagmus, Pathologic/diagnosis
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Ocular Hypertension/diagnosis
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Prognosis
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Retina/abnormalities
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Retrospective Studies
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Visual Acuity/*physiology
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Young Adult
4.Bilateral Spontaneous Anterior Lens Dislocation in a Retinitis Pigmentosa Patient.
Young A KWON ; Soong Hwan BAE ; Yong Ho SOHN
Korean Journal of Ophthalmology 2007;21(2):124-126
PURPOSE: To report a case of bilateral spontaneous anterior lens dislocation associated with retinitis pigmentosa (RP). METHODS: A 45-year-old male with RP presented with elevated intraocular pressure (IOP) in the right eye and was treated with laser iridotomy (LI). After LI, complete crystalline lens dislocation into the anterior chamber occurred. Surgical intervention, including anterior vitrectomy, intracapsular cataract extraction (ICCE), and IOL scleral fixation was performed. Two years later, the same episode occurred in his left eye and a similar treatment was done. RESULTS: Surgery was successful in both eyes. CONCLUSIONS: This is the first report of bilateral spontaneous anterior lens dislocation in a RP patient.
*Anterior Chamber
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Cataract/complications/diagnosis
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Cataract Extraction
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Electroretinography
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Follow-Up Studies
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Humans
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Iris/surgery
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Laser Therapy/adverse effects
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Lens Implantation, Intraocular/methods
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Lens Subluxation/diagnosis/*etiology/surgery
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Male
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Middle Aged
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Ocular Hypertension/complications/physiopathology/surgery
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Retinitis Pigmentosa/*complications/diagnosis/surgery
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Sclera/surgery
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Suture Techniques
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Visual Fields
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Vitrectomy