PURPOSE: Although the metabolic syndrome (MS), which can lead to the development of cardiovascular disease (CVD) or diabetes mellitus (DM), is increasing in children and adolescents, no unified criteria have been established, and little attention has been paid to its occurrence in Korean children and adolescents. In this study, we compared the prevalence of the MS in Korean children and adolescents using the criteria which were modified for children and adolescents by Cook et al., Cruz and Goran, and Ferranti et al. MATERIALS and METHODS: The study population was a nationwide representative sample of 3,431 children and adolescents (1,828 boys and 1,603 girls) from the 2001 Korean National Health and Nutrition Examination Survey (KNHANES), who were aged 10-19 years (mean 14.1 +/- 2.8), underwent a physical examination, and fasted for 8 hours before collecting blood samples. RESULTS: The rates of the MS were 6.1, 5.3, and 14.0% according to the criteria of Cruz and Goran, Cook et al., and Ferranti et al., respectively, and the agreement rate of the three sets of criteria was 88.7%. CONCLUSION: Unified criteria for the MS and a strategy for reducing obesity in children and adolescents will be necessary to prevent the occurrence of this syndrome.
Adolescent ; Adult ; Child ; Female ; Humans ; Korea/epidemiology ; Male ; Metabolic Syndrome X/classification/*epidemiology ; Obesity/classification/epidemiology

Asian Continental Ancestry Group ; Body Weight ; China ; epidemiology ; Humans ; Obesity ; classification ; epidemiology ; metabolism

PURPOSE: The study was conducted to describe body shapes of school age children using the degree of obesity index (DOI) and body mass index obesity index classified by the Ministry of Education, Science and Technology (M-BOI) and Seoul Metropolitan Office of Education (S-BOI). METHODS: In this cross sectional descriptive study health screening data for school children collected in 2007 was used. RESULTS: Data were analyzed for 2,193 4th-6th grade boys (52%) and girls who attended 4 schools in rural areas. DOI determined that only 44.3% of students had average weight. This proportion was much lower than the results of other methods (74.3-77.6%). All three methods defined girls (51.3-61.8%) as skinnier than boys. Skinny and average body shaped children classified by DOI and obese children classified by S-BOI were heavier and taller and presented higher degrees of obesity (DO) and BMI scores than by other methods. M-BOI and S-BOI presented statistically significant positive correlations with weight, height, DO and BMI, while DOI was not correlated with height. CONCLUSION: BMI based body shape classifications provide a more rigorous classification of body shape which are favorable for school health professionals with limited resources and policy makers for internationally comparable references.
Anthropometry ; Body Height ; *Body Mass Index ; Body Weight ; Child ; Cross-Sectional Studies ; Female ; Humans ; Male ; Obesity/*epidemiology ; Students/classification

The aim of this study was to determine the appropriate cut-off values for visceral fat area and waist circumference (WC) associated with an increase in risk for obesity-related disorder, and to validate diagnostic criteria for abdominal obesity and the metabolic syndrome in a Korean adult population. We included 413 subjects (174 men and 239 women) for this study. Subjects were selected among Korean adults who visited the obesity clinic at St. Mary's Hospital and Kangnam St. Mary's Hospital from January 1999 to August 2005. All patients had computed tomography performed. The cut-off value, of visceral fat area associated with an increase risk of obesity-related disorder, according to the receiver operating characteristics curve, was 103.8 cm2 (sensitivity 74.5%, specificity 64.7%, p<0.001). The cut-off value for the WC was 89.8 cm in men (sensitivity 84.7%, specificity 91.7%, p<0.005) and 86.1 cm in women (sensitivity 83.9%, specificity 62.9%, p<0.001). Based on the results of this study, the visceral fat area associated with an increased risk of obesity-related disorder in Korea was 103.8 cm2 and the WC was 89.8 cm in men and 86.1 cm in women.
Sensitivity and Specificity ; Reproducibility of Results ; Prevalence ; Obesity/classification/*diagnosis/*ethnology ; Male ; Korea/epidemiology ; *Intra-Abdominal Fat ; Humans ; Health Status Indicators ; Female ; *Body Size ; *Body Composition ; Anthropometry/*methods ; Adult ; *Abdomen

Sarcopenia was listed in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) as M62.84, on October 1, 2016. Sarcopenia is primarily associated with metabolic diseases, such as diabetes, obesity, and cachexia, as well as chronic renal failure, congestive heart failure, and chronic obstructive pulmonary disease. Sarcopenia is also significantly associated with osteoporosis in elderly populations and the combined disease is defined as osteosarcopenia. Several studies have confirmed that sarcopenia and osteoporosis (osteosarcopenia) share common risk factors and biological pathways. Osteosarcopenia is associated with significant physical disability, representing a significant threat to the loss of independence in later life. However, the pathophysiology and diagnosis of osteosarcopenia are not fully defined. Additionally, pharmacologic and hormonal treatments for sarcopenia are undergoing clinical trials. This review summarizes the epidemiology, pathophysiology, diagnosis, and treatment of osteosarcopenia, and includes Korean data.
Aged ; Cachexia ; Diagnosis ; Epidemiology ; Heart Failure ; Humans ; International Classification of Diseases ; Kidney Failure, Chronic ; Korea ; Metabolic Diseases ; Obesity ; Osteoporosis ; Pulmonary Disease, Chronic Obstructive ; Risk Factors ; Sarcopenia

BACKGROUND: Knee osteoarthritis is highly prevalent, especially among the elderly. However, its risk factors have not been well identified, especially in the Korean population. This study aimed to assess the epidemiologic characteristics and risk factors of knee osteoarthritis in the Korean population. METHODS: Data of 2,280 (1,295 women) participants of the 2013 Korea National Health and Nutrition Examination Survey aged ≥50 years who underwent knee radiography were analyzed. According to the American College of Rheumatology clinical/radiographic classification criteria, knee osteoarthritis was defined as knee pain and radiographic knee osteoarthritis. The association between risk factors and knee osteoarthritis was analyzed using the chi-square test and binominal logistic regression. RESULTS: The participants had an average age of 62.6 years; 56.8% of them were women. The average body mass index was 24.2 kg/m2, and 296 (13%) participants were diagnosed with knee osteoarthritis. After adjustment for multiple risk factors, age of ≥65 years (adjusted odds ratio [OR], 2.552; 95% confidence interval [CI], 1.868–3.486), female sex (OR, 2.050; 95% CI, 1.275–3.295), obesity (body mass index, ≥25.0 kg/m2; OR, 1.563; 95% CI, 1.191–2.051), hypertension (OR, 1.394; 95% CI, 1.052–1.846), low educational level (lower than or equal to elementary school: OR, 4.761; 95% CI, 2.131–10.635; middle school: OR, 3.184; 95% CI, 1.375–7.369), and low strength exercise frequency (<2 times/wk; OR, 1.829; 95% CI, 1.202–2.784) increased the risk of knee osteoarthritis. CONCLUSION: Old age, sex, obesity, hypertension, low educational level, and low strength exercise frequency were found to be risk factors for knee osteoarthritis.
Aged ; Body Mass Index ; Classification ; Epidemiology ; Female ; Humans ; Hypertension ; Knee ; Korea ; Logistic Models ; Nutrition Surveys ; Obesity ; Odds Ratio ; Osteoarthritis ; Osteoarthritis, Knee ; Prevalence ; Radiography ; Rheumatology ; Risk Factors

OBJECTIVEFor prevention of obesity in Chinese population, it is necessary to define the optimal range of healthy weight and the appropriate cut-off points of BMI and waist circumference for Chinese adults. The Working Group on Obesity in China under the support of International Life Sciences Institute Focal point in China organized a meta-analysis on the relation between BMI, waist circumference and risk factors of related chronic diseases (e.g., high diabetes, diabetes mellitus, and lipoprotein disorders).

METHODS13 population studies in all met the criteria for enrollment, with data of 239,972 adults (20-70 year) surveyed in the 1990s. Data on waist circumference was available for 111,411 persons and data on serum lipids and glucose were available for more than 80,000. The study populations located in 21 provinces, municipalities and autonomous regions in mainland China as well as in Taiwan. Each enrolled study provided data according to a common protocol and uniform format. The Center for data management in Department of Epidemiology, Fu Wai Hospital was responsible for statistical analysis.

RESULTS AND CONCLUSIONThe prevalence of hypertension, diabetes, dyslipidemia and clustering of risk factors all increased with increasing levels of BMI or waist circumference. BMI at 24 with best sensitivity and specificity for identification of the risk factors, was recommended as the cut-off point for overweight, BMI at 28 which may identify the risk factors with specificity around 90% was recommended as the cut-off point for obesity. Waist circumference beyond 85 cm for men and beyond 80 cm for women were recommended as the cut-off points for central obesity. Analysis of population attributable risk percent illustrated that reducing BMI to normal range (< 24) could prevent 45%-50% clustering of risk factors. Treatment of obese persons (BMI > or = 28) with drugs could prevent 15%-17% clustering of risk factors. The waist circumference controlled under 85 cm for men and under 80 cm for women, could prevent 47%-58% clustering of risk factors. According to these, a classification of overweight and obesity for Chinese adults is recommended.

Adult ; Aged ; Body Mass Index ; Body Weight ; China ; Diabetes Mellitus ; epidemiology ; ethnology ; Female ; Health Surveys ; Humans ; Hypertension ; epidemiology ; ethnology ; Male ; Middle Aged ; Obesity ; classification ; complications ; ethnology ; Reference Values ; Risk Factors ; Sex Factors ; Thorax ; anatomy & histology

BACKGROUND/AIMS: The aim of this study was to assess the association between the number of existing permanent teeth and chronic kidney disease (CKD) in a representative sample of the elderly Korean population. METHODS: A total of 2,519 subjects who participated in the Korean National Health and Nutrition Examination Survey were cross-sectionally examined. The number of existing permanent teeth was evaluated by clinical oral examination. CKD was defined based on definition and classification by Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guidelines. Multivariable logistic regression analyses were performed controlling for age, gender, income, education, tooth-brushing frequency, periodontitis, state of dentition, smoking, alcohol consumption, hypertension, obesity, diabetes mellitus, and hypercholesterolemia. Subgroup analyses by age and gender were also performed. RESULTS: The number of teeth was significantly associated with CKD after controlling for all potential confounders (adjusted odds ratio [AOR], 1.67; 95% confidence interval [CI], 1.04 to 2.70 for lower number of teeth; AOR, 1.59; 95% CI, 1.14 to 2.23 for moderate number of teeth). In the subgroup analyses, the association was highlighted in females aged 75 years over (AOR, 2.55; 95% CI, 1.05 to 6.20 for lower number of teeth; AOR, 1.95; 95% CI, 1.01 to 3.80 for moderate number of teeth). CONCLUSIONS: Our findings suggest that the number of existing permanent teeth may be associated with CKD among Korean elderly.
Aged* ; Alcohol Drinking ; Classification ; Dentition ; Diabetes Mellitus ; Diagnosis, Oral ; Education ; Epidemiology ; Female ; Humans ; Hypercholesterolemia ; Hypertension ; Kidney Diseases ; Logistic Models ; Nutrition Surveys ; Obesity ; Odds Ratio ; Periodontitis ; Renal Insufficiency, Chronic* ; Risk Factors ; Smoke ; Smoking ; Tooth*