Silicone has become one of the most extensively applied biomaterials in moderm medicine. But, silicone-related diseases are being observed with increasing frequency. We report a case of silicone granuloma of the face in a 44-year-old female patient who had been injected with liquid silicone for cosmetic purpose 20 years prior to visit. The patient presented with erythematous sclerotic plaque and large round brownish patch on the chin and left cheek, respectively. Histopathologically, there were many variable sized ovoid or round cavities surrounded by multinucleated giant cells and lymphohistiocytes. After 6 weeks of oral steroid treatment, mild improvement was noted.
Adult ; Biocompatible Materials ; Cheek ; Chin ; Female ; Giant Cells ; Granuloma* ; Humans ; Silicones*