1.Oligodontia: challenges in dental rehabilitation
Nur Adilah Ahmad Othman ; S. Nagarajan M.P. Sockalingam
Archives of Orofacial Sciences 2014;9(2):96-100
Oligodontia, although rare, may have significant impact on the quality of life of those affected with it. Provision of restorative treatment for these patients can be very challenging and demanding for clinicians, especially during the active growth phase. Nevertheless, the dental needs of these patients are real and should be addressed appropriately. The present case report described a restorative rehabilitative plan and execution of different restorative treatment modalities in a 14-year-old patient with oligodontia. The challenges faced in the provision of dental care were highlighted. The treatment outcome showed a positive psychological impact on the well-being of the patient based on parental observations.
Anodontia
2.Detection of virulence genes and antibiotic resistance profiles of Staphylococcus aureus isolated from animals
Asinamai Athliamai Bitrus ; Zakaria Zunita ; Siti Khairani Bejo ; Sarah Othman ; Nur Adilah Ahmad Nadzir
Malaysian Journal of Microbiology 2016;12(6):408-417-417
Aims: This study was designed to determine the virulence genes and antibiotic resistance profiles of Staphylococcus
aureus isolated from dogs, cats, chickens and horses.
Methodology and results: A total of 15 S. aureus isolates were used in this study. Antibiogram and screening of
virulence genes was carried out using disc diffusion method and polymerase chain reaction. The results obtained
showed that a total of 9 S. aureus isolates were resistant towards oxacillin (60%), 9 isolates were resistant towards
neomycin (60%) and 8 isolates were resistant towards tilmicosin (53%). Resistance to amoxicillin, tetracycline and
vancomycin was also observed in 6 (40%) of the isolates. Additionally, 5 (33%) of the isolates showed resistance
towards streptomycin and linzolide while 4 (27%) of the isolates were resistant towards rifampin, erythromycin and
mupirocin. Lastly, 3 (20%) of the isolates were resistant towards doxycycline. Intermediate resistance to amoxicillin and
doxycycline was also observed. Virulence gene profiling showed that 4 (26.7%) of the isolates were positive for hlβ and
SspA, 9 of the isolates (60%) showed positive for geh and 12 of the isolates (80%) showed positive for Set-1. Similarly,
2 (13.3%) of the isolates showed positive for etA and Seu while only 1 isolate (6.7%) showed positive for PVL and hlα.
None of the isolates were positive for tst-1 and etB.
Conclusion, significance and impact of study: This study revealed reduced susceptibility and multiple drug
resistance (MDR) in four isolates, and susceptibility to all antibiotics in two isolates in addition to low carriage rate of
virulence gene in all isolates. Thus, indicating resistance development in majority of the isolates and the need to regulate
indiscriminate use of antibiotics in animals.
Staphylococcus aureus