A clinical study was made on 117 cases of benign prostatic hyperplasia admitted to the Department of Urology, Chungnam University Hospital during the period from January 1974 to August 1982. The results were summarized as follows: 1. Common symptoms were dysuria (82.1%) and urinary retention (41.0%). 2. Gross or microscopic hematuria was noticed in 48 cases (41.0%). 3. The degree of prostatic enlargement by rectal palpation was not related to the severity of symptoms. 4. Pulmonary disease (19.5%) and cardiac disease (12.8%) were frequently associated with B.P.H. 5. Treatment consisted of suprapubic of retropubic prostatectomy in 94 cases, TUR in 7 cases and cystostomy in 10 cases. 6. Postoperative complications were urinary incontinence (34%), wound problem (9.7%), delayed bleeding (8.7%), and urinary tract infection (4.8%). 7. Mean weight of removed prostatic tissue was 31.3gm.
Chungcheongnam-do ; Cystostomy ; Digital Rectal Examination ; Dysuria ; Heart Diseases ; Hematuria ; Hemorrhage ; Lung Diseases ; Postoperative Complications ; Prostatectomy ; Prostatic Hyperplasia* ; Urinary Incontinence ; Urinary Retention ; Urinary Tract Infections ; Urology ; Wounds and Injuries

The incidence of giant condyloma acuminata of the penis is extremely rare. Although they are considered clinically malignant, the real possibility of malignant changes from them are controversial even among the investigators but cannot be entirely overlooked. Therefore, attention must be focused on this fact, in our conclusion. Two cases of malignancy of the penis which have apparently been transformed from giant condyloma acuminata of the penis are herein presented with review of related literatures. Case I: Sixty nine year old male patient complained of a fungating mass on the sulcus coronaris of the penis with ulceration and bleeding from the mass. Biopsy confirmed giant condyloma acuminata and subsequently circumcision and electrocoagulation were performed. Pathological specimen taken after 4 months because of the recurrence of the mass on the same region showed squamous cell carcinoma of the penis and amputation of penis was performed. Case II: Sixty eight old male patient complained of a growing mass and pain on glans penis. This patient also underwent circumcision and electrocoagulation according to the biopsy finding of giant condyloma acuminata. But 1 year later with recurrence of the mass on the same region, the pathological finding revealed squamous cell carcinoma of penis.
Amputation ; Biopsy ; Carcinoma, Squamous Cell ; Circumcision, Male ; Electrocoagulation ; Female ; Hemorrhage ; Humans ; Incidence ; Male ; Penile Neoplasms ; Penis ; Recurrence ; Research Personnel ; Ulcer

This study was carried out to investigate the response of interphase Y chromosome to some drugs and toxins by observing the rate of leukocytes showing Y-body in the peripheral blood. The interphase Y chromosomes of blood leukocytes were stained with quinacrine mustard and the animals used were rabbits, rats and guinea pies. Y-bodies of leukocytes were studied in the animals as well as in man. Changes in positive rate of Y-body in leukocytes and total leukocyte count were observed in the rabbits administered with drug or toxin. The results concerning the rate of Y-body were as follows: 1. Y-bodies were present in the blood leukocytes of the animals. However positive rates in mononuclear and polymorphonuclear leukocytes were lower in animals that in man. The positive rate of Y-body was higher in mononuclear leukocytes than in polymorphonuclear leukocytes in the animals as in man. 2. Bacterial toxins such as typhoid, D.P.T. and cholera vaccines and anticancer drugs such as busulfan and endoxan reduced the positive rates of Y-body both in mononuclear leukocytes and in polymorphonuclear leukocytes. 3. Benzene known as bone marrow toxin reduced the positive rate of Y-body in mononuclear leukocytes, but not that in polymorphonuclear leukocytes. Quinine known as general protoplasmic poison reduced the positive rate of Y-body not only in mononuclear leukocytes but also in polymorphonuclear leukocytes. 4. Antibiotics such as tetracycline and chloramphenicol and steroid hormones such as estrogen, testosterone and prednisolone had no effects on the positive rate of Y-body both in mononuclear leukocytes and in polymorphonuclear leukocytes.
Animals ; Anti-Bacterial Agents ; Bacterial Toxins ; Benzene ; Bone Marrow ; Busulfan ; Chloramphenicol ; Cholera Vaccines ; Cyclophosphamide ; Cytoplasm ; Estrogens ; Guinea ; Interphase ; Leukocyte Count ; Leukocytes* ; Leukocytes, Mononuclear ; Neutrophils ; Prednisolone ; Quinacrine Mustard ; Quinine ; Rabbits* ; Rats ; Testosterone ; Tetracycline ; Typhoid Fever ; Y Chromosome

This study was carried out to investigate the effect of Mycoplasma on sperm motility. It was suspected that a GUT infection due to Mycoplasma could be a possible cause of infertility. Human fresh spermatozoa from 57 healthy medical students were mixed and diluted with Mycoplasma groups. 37 specimens to T-mycoplasmas and 20 specimens to M. hominis were exposed with varying concentration from 10,000 to 1,000,000 colonies/ml of broth, respectively. Spermatozoal motility scale devised by Emmens and pH by pH paper were checked at serial time of hours in vitro. The following results were obtained. 1. There is no significant effect on sperm motility in pH change by Mycoplasma. 2. The sperm motility of control groups among pure semen, semen with normal saline and semen with broth solution were no statistically significant differences (p>0.05). 3. The statistically significant decreased sperm motility was watched in T-mycoplasmas experimental groups than that of control groups. The motility was much decreased with higher concentration of organisms (p<0.05). 4. The statistically significant decreased sperm motility was also watched in M. hominis experimental groups than that of control groups (p<0.05) The motility was much decreased with higher concentration of organisms.
Humans ; Hydrogen-Ion Concentration ; Infertility ; Mycoplasma* ; Semen ; Sperm Motility* ; Spermatozoa* ; Students, Medical ; Ureaplasma

A clinical observation was made on 30 patients of urologic surgery using the intestinal segment who had been admitted to the Department of Urology, Chungnam National University Hospital from May, 1976 to April, 1982. The results are as follows; 1. The age distribution of the most of cases were fifth and sixth decades (66.7%), and the male to female ratio was 3.3 to 1. 2. Majority of underlying diseases was bladder tumor (76.6%). The other causes were neurogenic bladder (10.0%), Vesicovaginal fistula (10.0%) and contracted bladder (3.3%). 3. Of the 30 cases of urinary diversion, 24 cases were ureteroileocutaneostomy with or without total cystectomy, 3 cases were ureterocolocutaneostomy with total cystectomy, 2 cases were ureteroileocecocutaneostomy with total cystectomy and 1 case was augmented ileocecocystoplasty. 4. Operation mortality was 10%, in which underlying diseases were bladder cancer. 5. Major complications were acute renal failure, septicemia, wound disruption, urine leakage, fecal fistula, ileus, bleeding, pneumonia and evisceration. 6. In the 23 cases of bladder cancer 21 cases were transitional cell carcinoma and 2 cases were adenocarcinoma. Most of the former were composed of stage B & C (66.7%) and grade II & III (71.4%). 7. In cases of malignant disease the overall postoperative survival rate at 1, 3 and 5 years of bladder cancer were 73.9%, 50% and 20% respectively.
Acute Kidney Injury ; Adenocarcinoma ; Age Distribution ; Carcinoma, Transitional Cell ; Chungcheongnam-do ; Cystectomy ; Female ; Fistula ; Hemorrhage ; Humans ; Ileus ; Male ; Mortality ; Pneumonia ; Sepsis ; Survival Rate ; Urinary Bladder ; Urinary Bladder Neoplasms ; Urinary Bladder, Neurogenic ; Urinary Diversion ; Urology ; Vesicovaginal Fistula ; Wounds and Injuries

It was suspected that a GUT infection could be a possible cause of infertility. This study was carried out to investigate the effect of Trichomonas vaginalis and Gonococci on sperm motility. Human fresh spermatozoa from 50 healthy medical students were mixed and diluted with Trichomonas vaginalis and Gonococci. 30 specimens to Trichomonas vaginalis and 20 specimens to Gonococci were exposed with varying concentration from 10(4) to 10(6) organisms/ml of broth, respectively. Spermatozoal motility scale devised by Emmens was checked at serial time of hours in vitro. The following results were obtained: 1. The sperm motility of control groups among pure semen, semen with normal saline and semen with broth solution were no significant differences. 2. A significantly decreased sperm motility ensued in Trichomonas vaginalis experimental groups, 106 organisms/ml and broth extract contained metabolite, than control group. 3. There were no significant differences between control groups and experimental groups in Gonococci.
Humans ; Infertility ; Semen ; Sperm Motility* ; Spermatozoa* ; Students, Medical ; Trichomonas vaginalis* ; Trichomonas*

A clinical observation was made on the pediatric patients (under 15 years old) who had been admitted to the Department of Urology, Chungnam National University Hospita1, during the 6 year period from March. 1974 to February, 1980. The results were as follows: 1. During the period, pediatric in-patients were 101 of 825 total urologic in-patients giving a ratio of 12.2%. 2. The proportion of male to female pediatric in-patient was 6:8:1. 3. The school children(6 to 12 years of age) were most frequently seen and giving a rate of 49.5% of pediatric in-patients. 4. The most common disease was genitourinary anomaly giving a ratio of 45.5%. The hydrocele was 22.8%, genitourinary injury 11.9%, tumor 7.9%, renal tuberculosis 2% and others 9.9% 5. The most frequently involved organ was testis and scrotum giving a ratio of 52.4%, followed by urethra 21.8%, kidney 16.8% and bladder 5.0%. 6. Among 86 of 101 cases, 103 operations were performed. The most common operation was hydrocelectomy in 23 cases. The other operations were orchiopexy in 22 cases. chordectomy in 11 cases, urethroplasty in 11 cases, nephrectomy in 7 cases, hernioplasty in 6 cases and others. 7. The most common duration of hospital stay was from 1 to 2 weeks(55.4%).
Chungcheongnam-do ; Female ; Herniorrhaphy ; Humans ; Kidney ; Length of Stay ; Male ; Nephrectomy ; Orchiopexy ; Pediatrics ; Scrotum ; Testis ; Tuberculosis, Renal ; Urethra ; Urinary Bladder ; Urology*

This study was carried out to investigate the effect of sperm motility to some bacteria which were possible cause of infertility by genitourinary tract infection. Human spermatozoa, from 42 cases of healthy medical student, were exposed to E. coli (30 cases) and Staphylococcus aureus (12 cases) varying dilutions from 10(4), 10(5), 10(6) colonies/ml of normal saline and broth solution. Spermatozoal numerical motility scale devised by Emmens was checked at the serial time of hours in Vitro. The following results were obtained: 1. Sperm motilities of control groups among pure semen, semen with normal saline, semen with broth solution and semen with broth extract contained endotoxin were no significant differences. 2. A significantly decreased sperm motility ensued in E. coli experimental groups than control group. And the more concentrated bacteria the more significant decrease of sperm motility was observed. 3. There were no significant differences between control group and experimental groups in Staphylococcus aureus.
Bacteria* ; Humans ; Infertility ; Semen ; Sperm Motility* ; Spermatozoa* ; Staphylococcus aureus ; Students, Medical

144 in-patients with urinary tract tuberculosis during the period from 1965 to 1969 were observed statistically. These patients stand for 8.9% of the in-patients with male to female ratio 59.6%/40.4%. Most frequent age distribution slowed 21 to 30 years with 35.9% and next 31 to 40 years with 31.4%. And lateralization, right to left 49.3% to 41.0% and bilateral 9.7%. 47.8% of patients admitted the hospital within 6 months to 1 year after onset of symptoms, and 9.1% after 5 years. The most frequent subjective complaints was hematuria, dysuria and frequency with 41.6%, and flank pain or dullness, 30.4%. In 49.7% of cases, past history of tuberculosis was noted, of which 31.2% had pulmonary tuberculosis and 20.1% pleurisy. Tubercle bacilli were smeared positive in 49.7%. 66.7% of 102 patients showed subnormal in PSP test with criteria of 50% within 30 minutes and 70% within 2 hours. Of 113 intravenous pyelograms, functional changes revealed non-visualization 46.9%, delayed visualization 27.6%. The itemized classification based on Braasch and Emmett was similar order of frequency as original. Lattimer Grade IV and far advaced case were the most frequent in 30 retrograde pyelograms. Nephrectomy was 95% in 104 operated cases and 92 nephrectomized specimens disclosed all parenchymal tuberculous nodules, tuberculous mucosal lesion in 82%, cavities 70%, calcification 4.3%, and pyonephrosis 17%.
Age Distribution ; Classification ; Dysuria ; Female ; Flank Pain ; Hematuria ; Humans ; Male ; Nephrectomy ; Pleurisy ; Pyonephrosis ; Tuberculosis* ; Tuberculosis, Pulmonary ; Urinary Tract*

A clinical observation was made on the injuries of genitourinary tract of the in-patient in the department of urology, Chungnam National University Hospital during the period from March, 1974 to February, 1978. The results are as follows. 1. Of 403 cases hospitalized, 73 cases were injury of genitourinary tract, giving a ratio of 18.1 %. 2. The most prevalent age was from 21 to 40 for 49.3 %. The sex ratio, male to female, was 3.3:1. 3. There was increasing tendency of genitourinary tract injury annually. 4. Traffic accident, fall or straddle and kick or blow were the most frequent causes of the injury in 23.3 % respectively and the next was iatrogenic in 15.1 %. 5. The urethra was involved most frequently in 45.2 % and the next was bladder in 23.3 % the kidney in 19.2 %, the external genitalia in 8.2 % and the ureter in 4.1 %. 6. Among the 17 cases of bladder injuries, 10 cases were vesico-vaginal fistulas. All 9 patients taken repair of fistula, were cured successfully with first attempt. 7. Operation was performed in 5 cases of 14 renal injuries. 8. Three of 7 bladder ruptures were accompanied with pelvic bone fracture. 9. 10 of 33 urethral injuries were accompanied with pelvic bone fracture. Posterior urethral injury was more common in traffic accident with pelvic bone fracture and bulbous urethral injury was more common in straddle injury.
Accidents, Traffic ; Chungcheongnam-do ; Female ; Fistula ; Genitalia ; Humans ; Kidney ; Male ; Pelvic Bones ; Rupture ; Sex Ratio ; Ureter ; Urethra ; Urinary Bladder ; Urology