No abstract available.
Nuclear Medicine ; Precision Medicine

PURPOSE: We performed this study to evaluate reliability on interpretation of three phase bone scintigraphy (TPBS) in patients with post-traumatic complex regional pain syndrome (PT-CRPS). METHODS: Based on International Association for the Study of Pain guideline in 1994, 34 patients with PT-CRPS were selected for this study. Two nuclear medicine physicians evaluated identical TPBS according to the uptake pattern, extent and intensity of the lesion, and their agreements (kappa values) were analysed. The final diagnosis based on arbitrary criteria of each physician were compared with those obtained by the criteria for PT-CRPS established in this study, which are hyperactivity on all phases (criteria 1), hyperactivity of whole joints on delayed phase (criteria 2), and hyperactivity of either whole or focal joints on delayed phase (criteria 3). RESULTS: Intra-observer agreements were good for uptake pattern, intensity, and extent on TPBS. Inter-observer agreements were also good, except extent on blood pool phase (0.55). The inter-observer agreements on final diagnosis improved when criteria 1-3 were applied (0.77-0.88), compared to when physician's own criteria were used (0.63). Those also improved from 0.29 to 0.47-0.82 for acute stage, and from 0.37 to 1.0 for chronic stage. The sensitivities of chronic stage were relatively lower to those of acute stage. CONCLUSIONS: Inter-observer's variations in diagnosis of the patients with PT-CRPS using TPBS were observed. These results were attributed to different criteria set by observers. In order to improve agreement on interpretation of TPBS, common positive criteria should be established, especially considering uptake pattern and clinical stages.
Humans ; Joints ; Nuclear Medicine

PURPOSE: This editorial deals with the basic structures of medical papers in general and emphasizes the ethics of authors and reviewers. A majority of the content originated from educational material issued at the 2002 Annual Meeting for the Korean Committee of Medical Journal Editors. Current issues from the publication of the Korean Journal of Nuclear Medicine were also included.
Ethics ; Nuclear Medicine ; Publications

Radionuclide therapy has been continued for treatment of incurable diseases for past decades. Relevant evaluation of absorbed dose in radionuclide therapy is important to predict treatment output and essential for making treatment planning to prevent unexpected radiation toxicity. Many scientists in the field related with nuclear medicine have made effort to evolve concept and technique for internal radiation dosimetry. In this review, basic concept of internal radiation dosimetry is described and recent progress in method for dosimetry is introduced.
Nuclear Medicine ; Radiometry*

We set out to analyse the result of 142 hyperthyroidsm patients, treated with radioiodine from 1987 to 1997, and still on follow-up by the Depar. of Nuclear medicine, Lam Dong General hospital. Among 142 patients studied, there are 123 females, 19 males. Their ages ranged from 19 to 65 years old (mean 35+/-9.8).
Hyperthyroidism ; Nuclear Medicine

700 patients with the hyperthyroidism were examined according to the physical and disease condition. The classfication of age and gender, the evaluation of the clinical, paraclinical features, the thyroid function before and after the radioiodine therapy, the determination of the usual dosage as well as the complication of therapy were implemented.
Hyperthyroidism ; Nuclear Medicine

Radionuclide therapy has been an important field in nuclear medicine. In radionuclide therapy, relevant evaluation of internally absorbed dose is essential for the achievement of efficient and sufficient treatment of incurable disease, and can be accomplish by means of accurate measurement of radioactivity in body and its changes with time. Recently, the advances of nuclear medicine imaging and multi?modality imaging processing techniques can provide chance of more accurate and easier measurement of the measures commented above, in cooperation of conventional imaging?based approaches. In this review, basic concept for internal dosimetry using nuclear medicine imaging is summarized with several check points which should be considered in real practice.
Nuclear Medicine* ; Radioactivity ; Radiometry*

Radionuclide therapy has been an important field in nuclear medicine. In radionuclide therapy, relevant evaluation of internally absorbed dose is essential for the achievement of efficient and sufficient treatment of incurable disease, and can be accomplish by means of accurate measurement of radioactivity in body and its changes with time. Recently, the advances of nuclear medicine imaging and multi?modality imaging processing techniques can provide chance of more accurate and easier measurement of the measures commented above, in cooperation of conventional imaging?based approaches. In this review, basic concept for internal dosimetry using nuclear medicine imaging is summarized with several check points which should be considered in real practice.
Nuclear Medicine* ; Radioactivity ; Radiometry*

There is considerable interest in 188Re due to its favorable properties as a therapeutic radionuclide. 188Re and 99mTc act as a matched pair because of their similar chemical properties, and therefore methods of labeling with 99mTc can be applied to the labeling with 188Re. With appropriately chosen agents as carriers of 188Re, the labeling can be readily carried out using 188ReO4- in the presence of a reducing agent. 188Re radio pharmaceuticals based on 99mTc complexes have been synthesized and are currently being studied for clinical use. Some of them are shown to be suitable for therapeutic use and promising for radiotherapy in nuclear medicine.
Nuclear Medicine ; Radiopharmaceuticals ; Radiotherapy

Several thousands of patients with thyroid diseases were diagnosed and treated using the nuclear medicine techniques: Thyroid Radioiodine Uptake, thyroid related hormones determined by RIA or IRMA, thyroid gland scintigraphy. The effect on such test of the populations used iodine-salt was evaluated by authors, also in 330 patients with thyrotoxicosis were treated by I-131 during from 1998-2000 year. The results indicated that this is one of the best therapeutic methods which should be selected. During the last 20 years, very good achievements of nuclear medicine techniques used in diagnosis and treatment of thyroid diseases were collected at nuclear medicine dep. of Bach Mai hospital, but at the present time the imaging equipment Rectilinear Scanner MB 8100 is old and out of date. It must be changed by single photon emission computer tomography system or gamma camera.
Nuclear Medicine ; Thyroid Diseases