We reported a case of nasal malignant granular cell tumor. The patient was a 51 years old man who went to the hospital because of "right nasal intermittent bleeding for half a year". The pathological examination after resection showed malignant granular cell tumor. No recurrence was noted during a year after resection. The etiology and pathogenesis, clinical features, pathological features and treatments of malignant granular cell tumor were reviewed.
Epistaxis ; Granular Cell Tumor ; pathology ; surgery ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Nose ; Nose Neoplasms ; pathology ; surgery

Aged ; Chordoma ; pathology ; surgery ; Humans ; Immunohistochemistry ; Male ; Nose Neoplasms ; pathology ; surgery

Adult ; Female ; Humans ; Male ; Middle Aged ; Neurilemmoma ; pathology ; surgery ; Nose Neoplasms ; pathology ; surgery

Adenocarcinoma/pathology* ; Gene Rearrangement ; Humans ; Nasal Cavity/pathology* ; Nose Neoplasms/surgery* ; Paranasal Sinus Neoplasms/surgery* ; Paranasal Sinuses/pathology*

OBJECTIVE: To summarize clinical features, diagnosis, differential diagnosis, treatment and prognosis of basal cell adenocarcinoma. METHOD: A retrospective study were subjected to one case with basal cell adenocarcinoma of the nasal septum, and the related literature were reviewed. RESULT: Basal cell adenocarcinoma often occurred in the salivary glands and minor salivary glands of salivary palate and other parts. The symptoms mainly presented with a local lump. Major treatment method was radical surgical resection and, if necessary, supplemented by radiotherapy. CONCLUSION Basal cell adenocarcinoma is rare seen in the salivary gland tumors. It has a tendency of low-grade malignancy but need long-term follow-up of a large samples.
Adenocarcinoma ; radiotherapy ; surgery ; Aged ; Humans ; Male ; Nasal Septum ; pathology ; Nose Neoplasms ; radiotherapy ; surgery ; Retrospective Studies

Endoscopy ; Humans ; Male ; Middle Aged ; Myoepithelioma ; surgery ; Nasal Septum ; pathology ; Nose Neoplasms ; surgery

Adult ; Female ; Humans ; Nasal Mucosa ; pathology ; Nose Neoplasms ; diagnosis ; surgery ; Papilloma ; diagnosis ; surgery

Histiocytes/pathology* ; Humans ; Lymphoma, Extranodal NK-T-Cell/pathology* ; Nose Neoplasms/surgery*

OBJECTIVE: To explore the application of inner plate of frontal sinus-epidural approach in the treatment of anterior skull base cranio-nasal communication tumors. METHOD: A study of 6 cranio-nasal communication tumor patients was undertaken. They were treated with lateral rhinotomy-inner plate of frontal sinus-epidural approach to remove tumor. RESULT: The tumors in all the 6 patients were completely resected. The follow-up study during the following 2 years revealed that 5 patients had good facial appearances and showed no tumor recurrence, no cerebrospinal rhinorrhea, no meningoencephalocele, no frontal collapse, and other complications. CONCLUSION The surgical approach in the treatment of Cranio-nasal communication tumors needs to be chosen according to the tumor size, location and nature. Lateral rhinotomy-inner plate of frontal sinus-epidural approach can be carried out independently by the head and neck surgeons. It is a valuable surgical treatment with minimal invasion, short surgery time, little damage to brain, and easy pyrosis of skull base.
Adult ; Epidural Space ; surgery ; Female ; Frontal Sinus ; surgery ; Humans ; Male ; Middle Aged ; Nose Neoplasms ; parasitology ; surgery ; Paranasal Sinus Neoplasms ; pathology ; surgery ; Skull Base Neoplasms ; pathology ; surgery

Objective:To compare the clinical effects and complications of surgery + chemotherapy and radiotherapy + chemotherapy in patients with nasopharyngeal carcinoma recurrence, so as to compare the safety and efficacy of two different therapeutic methods. Methods:A retrospective analysis was performed on 40 patients with recurrent nasopharyngeal carcinoma after radiotherapy and chemotherapy admitted to our hospital from January 2016 to June 2020. Among them, 26 patients were treated with surgery. The recurrent tumor was removed under nasal endoscope, and the frozen resection margin was negative during the operation. Chemotherapy was continued for stage Ⅲ and Ⅳ patients from 3 to 5 weeks after surgery. Fourteen patients received secondary radiotherapy and chemotherapy. Postoperative complications and survival rate were observed. Results:There were 14 patients in the secondary chemoradiotherapy group（control group） and 26 patients in the nasal endoscopic surgery group（observation group）. Among the 26 patients, 19 patients underwent nasal septal mucosal repair, 5 patients underwent temporal muscle flap repair, 2 patients underwent submental flap repair, 2 patients had nasal septal mucosal flap necrosis and cerebrospinal fluid leakage, and the temporal muscle flap was used for secondary repair in the second stage operation, and 8 patients needed cervical lymph node dissection. The patients recovered well after surgery, and the patients in stage Ⅲ and Ⅳ were treated with chemotherapy after 3 weeks to 5 weeks according to the patient's wound condition. There were significant differences in the incidence of complications and 1-, 2-, and 3-year survival rates between the two groups（P<0.05）. Conclusion:Patients with recurrent nasopharyngeal carcinoma can be treated by nasal endoscopic surgery to remove the tumor, and the use of pedicled nasal septal mucosal flap or temporal muscle flap for skull base reconstruction, The operation can effectively prevent major complications such as internal carotid artery rupture and hemorrhage, and improve the survival rate and quality of life of patients. It provides a safe and effective treatment for patients with recurrent nasopharyngeal carcinoma.
Humans ; Plastic Surgery Procedures ; Nasopharyngeal Carcinoma/surgery* ; Retrospective Studies ; Quality of Life ; Skull Base/surgery* ; Nose Diseases/pathology* ; Nasopharyngeal Neoplasms/pathology*