1.Effects of Hibiscus sabdariffa Linn. Aqueous Extract on Oxidative Stress and T Lymphocyte Population in Spleen of Streptozotocin-induced Diabetic Rats
Nor Malia Abd Warif ; Asyraf Akmal Ayob ; Wan Marahaini Wan Razali ; Siti Balkis Budin ; Satirah Zainalabidin ; Jamaludin Mohamed
Malaysian Journal of Health Sciences 2014;12(1):15-21
Disturbances in immune system contribute to chronic infection among diabetic patients. Hibiscus sabdariffa L. (roselle)
fruit extract has been scientifi cally proven to possess antioxidant, antidiabetic and antiinfl ammatory properties. The
aim of this study was to investigate the effects of H. sabdariffa fruit extract against oxidative stress parameter and
T lymphocyte population in spleen of streptozotocin (STZ) induced diabetic rats. Male Sprague-Dawley rats were injected
with 45 mg/kg STZ to induce diabetic condition and further treated with 100 mg/kg H. sabdariffa fruit aquoeus extract
daily for 28 days. Spleen was harvested to determine the oxidative stress indicators and quantifi cation of T lymphocytes.
The results showed a signifi cant decreased in the number of spleen cells and spleen weight in the diabetic rats compared
with control rats. However, there were no signifi cant changes in the level of malondialdehyde (MDA), protein carbonyl and
superoxide dismutase (SOD) activity the percentage of spleen CD3+ CD4+ and CD3+ CD8+ T lymphocytes amongst groups
of study. In addition, histology observation showed no pathological alteration in spleen histology of diabetic rats. The
fi ndings suggested that aqueous extract of H. Sabdariffa fruit supplementation has no effect on the oxidative stress and
the percentage of CD3+ CD4+ and CD3+ CD8+ T lymphocytes in spleen of diabetic rats
2.Dietary Intake, Levels Of Trace Elements And Intelligence Quotient (Iq) Among Huffaz Students From Selected Tahfiz Schools In Selangor
Farah Wahida IBRAHIM ; Santibuana Abd RAHMAN ; Nor Malia Abd Warif ; Ahmad Rohi GHAZALI ; Faisal ARIFFIN ; Ismarulyusda ISHAK ; Nur Farahin Abdul Rahman ; Dzalani HARUN ; Hanis Mastura YAHYA ; Sabri MOHAMAD
Malaysian Journal of Health Sciences 2018;16(Special Issue (Article)):129-136
Tahfiz education has been well accepted by Muslims in Malaysia. Memorizing the Quran through rote learning can assistin improving the brain ability to process, store information and build memory. In addition, dietary intakes were reportedto contribute in the process of memorizing the Quran and to increase the levels of intelligence (IQ) among huffaz students.This cross-sectional study was conducted to measure and to determine the correlation between IQ and dietary intakeas well as between IQ and the level of trace elements among students in selected tahfiz schools and non-tahfiz school inSelangor. Questionnaires were used to obtain demographic data. Dietary intake was assessed via 3 days dietary record.Levels of trace elements in the nail samples were analyzed by using ICP-MS. Test for intelligence using WASI-II wasconducted to measure the students’ IQ. The results showed that there was a moderate positive correlation between IQ andcarbohydrate (r = 0.425, p < 0.001, a weak positive correlation between IQ and energy (r = 0.260, p < 0.05), vitaminB6 (r = 0.189, p < 0.05), vitamin B12 (r = 0.207, p < 0.05) and vitamin C (r = 0.211, p < 0.05). The levels of traceelements in nail samples showed no correlation with IQ, whereas there were moderate positive correlations between IQand dietary zinc (r = 0.375, p < 0.001) as well as between IQ and dietary iron (r = 0.303, p < 0.001). There was also amoderate positive correlation between IQ and the level of memorization (r = 0.375, p < 0.001). The results of stepwisemultiple linear regression showed that al-Quran memorization influence the level of IQ by 20 %. As a conclusion, dietaryintake of certain nutrients including energy, vitamins and selected trace elements can potentially improve memorizationactivities and also IQ.