In recent years, due to increased drug use global generic drugs in 2019, the industry generated 79 billion U.S. dollars in generic prescription drug revenue worldwide. Until 2026, the global prescribed generics market is expected to exceed 100 billion U.S. dollars.
The study of generic drugs will be based on the list of comparative products approved by the World Health Organization. The World Health Organization has approved the International List of Essential medicines of international comparator products based on the ANNEX-7 and ANNEX-8. That list includes a total of 572 international comparator products.
Generic drugs has an important role in the market of any country, and generic drugs are required to be similar to comparator products in terms of therapeutic activity, quality, and safety. In multi sources generic drug is equivalent to the treatment of the comparable product, allowing the product to be used as a substitute for analysis.
Some results of recent studies of Ibuprofen is mentioned above here.
In 2010 in Madrid, Spain, the study Investigation on the possibility of biowaivers for Ibuprofen was conducted by Covadonga Lvarez, Ignacio Nunenz, Juan J. Torrado and John Gordon. The aim of the study was to investigate the ability of in vitro dissolution to ensure bioequivalence of ibuprofen products. Ibuprofen is a Biopharmaceutics Classification System (BCS) class II drug with low solubility at pH 1.2 and 4.5 and high solubility at pH 6.8. In vivo studies were performed following the updated Declaration of Helsinki, with the approval of the Ethical Committee for Clinical Re- search of the Hospital and the Spanish Agency for Medicines and Health Care Products.
In-vitro evaluation of the pharmaceutical quality of some ibuprofen tablets dispensed in Nigeria, University of Benin, Department of Pharmaceutics and Pharmaceutical Technology, analyzed Florence E. Eichie*, Ikhuoria M. Arhewoh and Oliver C. Ezeobi. The Ibuprofen tablets were assessed according to British Pharmacopoeia (BP), and unofficial standards as recommended by the manufacturers. Of the 19 brands of tablets assessed, 12 brands passed the uniformity of content test while 15 brands passed the disintegration test and only four brands passed the dissolution test. Ibuprofen tablets dispensed in Nigeria varied considerably in their pharmaceutical quality.
In 2015 in Nigeria, Benin City, University of Benin, Department of Pharmaceutics and Pharmaceutical Technology, Studies of comparative UV−HPLC analysis of ten brands of ibuprofen tablets. Those studies investigated the pharmaceutical equivalence of ten brands of ibuprofen tablets (400 mg) purchased from pharmacies in Benin City, Nigeria. According to the results of the study, the weight of the total brand of drugs varies significantly, fluctuates between 6.14-15.93kp due to the action of pressure, and the melting point does not meet the requirements of brands B and G. Drug decomposition brands C, F, H, I meet the requirements, but the solubility indicators D, E, G, I, J inadequate requirements. Brands C and D inadequate requirements for determining the content of ibuprofen in ultraviolet light. However, all brands of drugs approved requirements for HPLC.
In 2020 in Mekelle, Ethiopia, Comparative In Vitro Quality Evaluation of Different Brands of Ibuprofen Tablets Marketed. Studies included seven brands of 400 mg lm coated ibuprofen tablets were randomly purchased from different pharmacies and drug stores in Mekelle. Weight uniformity, hardness, friability, disintegration, dissolution and assay of drug content were performed based on specications stipulated in the British Pharmacopeia (BP) and the United State Pharmacopeia (USP).
All the evaluated products of ibuprofen tablets marketed in Mekelle were within the acceptable compendial limits based on the in vitro results of the study except product IBU-E which failed in the disintegration test.
The aim of the study to determine the in vitro quality of some domestic and imported ibuprofen drugs.

Mongolian health human resources’ main goal is to provide effective and indiscriminate service that is evenly distributed among each individual in country. In order to achieve its goal, the general health policy should focus on its human resources management. This research work was done with document research method and got all the necessary information from databases of Public Health Development Center, Mongolian National statistical agency, Ministry of Health and Ministry of Education Culture and Science. There are 32.4 chief doctors, 37.2 nurses and 24 other health employees assigned to work for 10000 people from the study of 2016. Comparing this study with the previous year’s study, the number of the doctors has gone up by 0.8, but the number of the nurses has gone down by 0.3. Due to the WHO’s statistic, the number of the patients per doctor is considered to be low. The exact population of Mongolia is 3.119.935 in 2016. To compare the population spread through the country, Ulaanbaatar, capital city, has the highest density of population. The number of the hospitals and doctors were enough. Actually it was lower than world standard (500 patients per a doctor). Even the number of the doctors are enough, in remote area, it is not enough. In the whole country there are 309 patients per doctor, 237 patients per doctor in Ulaanbaatar and 433 patients per doctor in isolated areas. In conclusion, the human resource distribution is not even in the public health care.

BACKGROUND. In the worldwide every 40 seconds one person takes their life, annually 1 million people die on Earth by the means of suicide. Regardless of gender it is one of the main 3 causes of death in the population aged between 15-29. There have a tendency to increase of suicide rates with each passing year in the Mongolia. Therefore, our study goal is to determine the utilized methods and to identify some of the factors influencing the escalation of this phenomenon. The data and materials were gathered by quantitative research method from the post-mortem examination reports provided from the central archive of National Institute of Forensic Science according to the descriptive research design. The fact that the bulk of the increasing suicide cases might be attributed to the unemployed and working-age men without any chronic illnesses suggests correlation with gender and socio-economic status.