1. Carbon monoxide’s exposure assessment of workers at ore industry
Nomin E ; Erdenechimeg E ; Naransukh D
Innovation 2015;9(4):59-61
Carbon monoxide comes up from the combustion of gas, wood and coal during the industrial processes and since it’s a tasteless, odorless, colorless gas it can be absorbed into body in a short time resulting acute intoxication.The result of planned inspection with laboratory analysis at Ore industrial workshops and fields located in Darkhan-Uul province conducted by Specialized Inspection Place in 2013 was higher than the permissible level which is indicated in Mongolian national standard of occupational hygiene MNS4990-2000 by 60.2 mg/m3 and was higher than the short time permissible exposing level which is indicated Occupational Safety and Health Agency (OSHA) of USA by 20 ppm, therefore we predicted that there is a pollution of carbon monoxide in present industry and conducted this study.For the determination of carbon monoxide exposure by workshops and departments, the average level of CO for workers was 17 mg/m3, maximum was 57.3 mg/m3, the average level was for dayworkers 44.9 mg/m3, for night workers it was 102mg/m3 and maximum was 427 mg/m3 in RIW. Identifying level of exposure by the type of workers, for servicemen were 96.2-427 mg/m3 for welders was 46.4 mg/m3 and mechanics was 140.5mg/m3 which were higher than others.Comparing the results of present study with the permissible level of Mongolian national standard of occupational hygiene MNS4990-2000, was higher by 50-120mg/m3 and with the 8 hours of time weighted average (TWA) of Occupational Safety and Hygiene Agency (OSHA), was higher by 20-80 ppm.
2.ЖИРЭМСЭН ЭМЭГТЭЙЧҮҮДИЙН ШҮДНИЙ ТУЛГУУР ЭДИЙН ӨВЧИН НЬ ЖИН БАГАТАЙ ДУТУУ НЯРАЙ ТӨРӨХ ЭРСДЭЛТ ХҮЧИН ЗҮЙЛ БОЛОХ НЬ
Nomin G ; Uyanga E ; Suvdanchimeg A ; Oyuntsetseg B
Innovation 2018;12(4):21-23
ХУРААНГУЙ.
Дутуу төрөлт нь анагаах ухаан төдийгүй нийгэм эдийн засгийн тулгамдсан асуудал юм. Дутуу болон жин багатай төрөх нь нярайн эндэгдэлийн тэргүүлэх шалтгааны нэг болж байна. Шүдний тулгуур эдийн үрэвсэлт өвчний үед зарим нянгийн бүрэлдэхүүн хэсгүүд нь жирэмсэлтийн явц ба ургийн хөгжилд нөлөөлж болдог гэдгийг харуулсан судалгааны үр дүнгүүд байдаг. Иймээс жирэмсэн эмэгтэйчүүдийн тулгуур эдийн өвчин нь нярайн дутуу болон жин багатай төрөх эрсдэлт хүчин зүйл болж байгаа эсэхийг судлахад энэхүү судалгааны зорилго оршино. Уг судалгааг эмнэлэгт суурилсан тохиолдол хяналтын загвараар Нийслэлийн Өргөө Амаржих Газар болон Эх Хүүхдийн Эрүүл Мэндийн Үндэсний Төв (ЭХЭМҮТ)-ийн нийт 90 оролцогчийг хамруулан хийж гүйцэтгэлээ. Тохиолдлын бүлэг 30 (37 долоо хоногоос бага тээлттэй, 2500 гр-aaс бага жинтэй нярай) оролцогч, хяналтын бүлэгт 60 (хэвийн тээлттэй) оролцогч хамрагдсан.
Судалгаанд оролцогчдийн шүд цоорох өвчний (ШЦӨ) тархалт хяналтын бүлэгт 99%, эрчим 8.32 ЦЛА/ш, тохиолдолын бүлэгт ШЦӨ тархалт 100%, эрчим 11.33 ЦЛА/ш байв. Амны хөндийн эрүүл ахуйн (АХЭА) үзүүлэлтийг үнэлэхэд хяналтын бүлэгт 2.4 буюу ‘’дунд’’, тохиолдолын бүлэгт 3.2 буюу ‘’муу’’ үнэлгээтэй байлаа. Тулгуур эдийн өвчин, шүдний чулуу (***p<0.008), шүд буйлны эмгэг хөндийн гүн 4-6 мм байх нь (***p<0.006) жин багатай дутуу нярай (ЖБДН) төрөх эрсдэлт хүчин зүйл болж байгаа нь статистик ач холбогдол бүхий үр дүнг үзүүллээ. Буйлны үрэвсэл нь ЖБДН төрөх эрсдэлийг 5.5 дахин нэмэгдүүлж байна. Community Periodontal Index of Treatment Needs (CPITN) үзүүлэлт нь АХЭА үзүүлэлтээс хамааралтай болох нь статистикийн хувьд ач холбогдолтой байлаа (***р<0.000). Тулгуур эдийн өвчин шүдний чулуу, шүд буйлны эмгэг хөндийтэй байх нь ЖБДН төрөх эрсдэлт хүчин зүйл болж байгаа нь судалгааны үр дүнгээс ажиглагдлаа.
3.Periodontitis as a potential risk factor for preterm low birth weight
Nomin G ; Uyanga E ; Suvdanchimeg A ; Oyuntsetseg B
Innovation 2018;12(4):67-
Preterm birth is not only health problem but also one of major socioeconomic issues. Preterm Low Birth Weight (PLBW) is leading causative factor of neonatal mortality. Some researches results showed that during periodontal inflammatory disorder some bacterial components could affect pregnancy and fetal development. Therefore aim of our study is to assess and confirm periodontal disease of pregnant females whether or not risk factor of PLBW.
We performed our study on the First Maternity Hospital and National Centre for Maternal and Child Health of Mongolia by clinical based case control method on 90 participants. Case group has 30 females (<37 weeks of gestation, and Neonates Birth Weight <2500), control group has 60 females (Normal birth) (ratio was 1:2).
Dental caries prevalence on control group was 99%, the mean of DFM/t was 8.32 “average”, prevalence of case group was 100%, and mean of DFM/t was 11.33, which was also “average”. Oral hygiene examination assessment was poor. Study results showed that patients with periodontal disease such as dental calculus (***p<0.008) and periodontal pocket with depth of 4-6mm (***p<0.006) were risk factors for PLBW. Gingivitis is increased to have PLBW baby by 5.5 times. CPITN index was highly associated with dental hygiene index and it was statistically significant. (***p<0.000).
Within the limits of this study poor periodontal health status of mothers may be a potential risk factor for a preterm low birth weight.
4.УРСГАЛ УСНЫ ЧИМЭЭГ ЭМЧИЛГЭЭНД АШИГЛАХ БОЛОМЖ
Dariimaa G ; Lkham-Edrene B ; Enkhjin B ; Nomin G ; Davaadulam E
Innovation 2017;11(2):103-107
In this study we aimed to check a hypothesis about water sound (WS) effect can
stimulate parasympathetic nervous system. A case-control study design was used. The
students in control group did not listen WS, whereas students in case groups had been
influenced under WSE by 3 different ways, including audio, video and shower. Data
base had been obtained by performance of stress test, measurements of systolic and
diastolic pressure, and counts of pulse. For statistical analysis, IBM SPSS 20.0 and Graphpad
prism 7.0 were used. Interestingly, 92% of total students had stress. There were no
differences between groups before WS effect. After WS effect, ANOVA test detected
differences in diastolic pressure (ANOVA, F=6.209, p=0.001), stress score (F=15.21,
p<0.001). Paired test was utilized to compare mean of values between before and post
WS measurements, finding SP (p=0.001), SS (p<0.001) categories. It showed an effective
WS influence. Chi-square test indicated that stress level of all students decreased significantly
(p<0.001). But there were no differences between 3 methods of water therapy. In
conclusion, WS has an effect of stimulation in immune system, useful for some diseases,
in which parasympathetic system decrease and sympathetic system increases.
5.Results of a study on relationship between the dental caries and physical growth among autism spectrum disorder
Nomin-Erdene E ; Delgertsetseg J ; Oyuntsetse B
Innovation 2019;13(1):40-45
Background:
Autism spectrum disorder (ASD) is characterized by impairments in social
interaction and communication, restricted patterns of behavior, and unusual sensory
sensitivities. Symptoms of autism occur in some infants, while some children are diagnosed
in 2-3 years. There was a direct and indirect relationship between the dental caries and the
physical growth among children. The study purpose was to determine the oral health and the
body growth status among children with Autism spectrum disorder.
Methods:
The study population consisted of 53 children, who were diagnosed as “ASD”
and approved by psychiatrist between the age of 3-18. The dental examination was done
under recommendation by WHO (2013) and oral hygiene index was calculated by FedorovVolodkina (1973). Body growth status was evaluated by Kaup and Rohrer’s index. The results
of the study were processed using statistical Stata-21 software.
Results:
The prevalence of dental caries among all children with Autism spectrum disorder
was 88.6% and mean DMFT score were 2.6±3.0 in the primary dentition, 6.1±3.8 in the mixed
and 4.0±2.3 in the permanent dentition. Children with good oral hygiene index were 32% of
all study population and poor were 68%. When we assessed the body growth status, normal
weight children were 52.8%, overweight children were 18.9% and lower weight was 28.3% of
all study poptulation.
Conclusion
We have found that the oral health and the body growth status among
children with ASD were poor.
6.Total phenolic content, antioxydant activity of thalictrum squarrosum steph.ex willd.
Tsend-Ayush B ; Solongo Ts ; Nomin M ; Pvrewdorj E ; Enkhjargal D ; Solongo A
Mongolian Journal of Health Sciences 2025;85(1):41-45
Background:
Since ancient times, humans have used medicinal plants for medicinal purposes, and they have been recognized as beneficial to health. The basis of the treatment of these plants is phytochemical substances and in modern times,
with the development of science and technology, the substances contained in these plants are extracted and medicinal
substances and drugs are produced to treat many diseases. There are more than 800 medicinal plants in Mongolia, and
their chemical structure and properties are studied in detail, biological activity and main features are discovered, and new
medicines are produced. From the Thalictrum squarrosum plant, 25 compounds have been identified, such as triterpenoids
with 17 carbon atoms in the cycloartane type ring, saponins, oleic acid glycosides, phytosterols and their glycosides etc.,
and the structures of 7 new compounds have been determined and the research on phenolic compounds and antioxidant
activity has been limited, which is the basis for this research.
Aim:
Determination of total phenolic content and antioxidant activity of Thalictrum squarrosum.
Materials and Methods:
Total phenolic compounds were determined spectrophotometrically using Folin-Chicolte color
reagent in 1.0 raw material of the Thalictrum squarrosum. Antioxidant activity was determined by DPPH, FRAB and
ABTS in sub-extracts of 4 groups.
Results:
The total phenolic compounds of Thalictrum squarrosum were determined to be 1.9±0.001%. In the study of
biological activity of Thalictrum squarrosum plants, the antioxidant activity of 4 groups of sub-extracts was tested by
DPPH method, and the IC50 of total alkaloids (pH 9-10) was 201.58±0.1 μg/ml, ethyl acetate sub-extract 94.34±0.66
μg/ml, aqueous extract 824.18±0.08 μg/ml, and butanol sub-extract 128.75±0.58 μg/ml. When tested by ABTS method,
the IC50 of total alkaloids (pH 9-10) was 35.83±0.44 μg/ml, ethyl acetate sub-extract 90.45±0.62 μg/ml, aqueous extract
104.19±0.93 μg/ml, dichloromethane sub-extract 156.44±0.48 μg/ml, and butanol sub-extract 170.03±0.61 μg/ml. When
tested for antioxidant activity at 800 μg/ml by the FRAB method, the ethyl acetate sub-extract was 8946.16±14.79 μg/ml,
the dichloromethane sub-extract was 1670.12±39.28 μg/ml, the butanol sub-extract was 4863.97±25.98 μg/ml, and the
total alkaloids (pH 9-10) were 4897.99±58.12 μg/ml.
Conclusion
The ethyl acetate extract of the plant Thalictrum squarrosum has been found to be highly antioxidant active
and total phenolic compound was 1.9±0.001%.
7.Correlation between the individual body constitution in traditional medicine and some biochemical parameters
Xilinqiqige ; Tserentsoo B ; Tsend-Ayush D ; Delgerekhzaya E ; Nomin-Erdene U ; Hao Feng ; Chang Qing ; Dorjbat S ; Siqin
Mongolian Journal of Health Sciences 2025;85(1):159-163
Background:
From the perspective of traditional medicine, researchers believe that the individual’s innate quality has
a reciprocal effect on the physiological level. The study of body-specific quality differences is important for improving
disease risk prediction, diagnosis, and treatment approaches. Therefore, explaining the features of traditional medicine
with some physiological parameters and establishing the relationship between them is clinically significant and important
for predicting disease risk and developing individualized treatment methods, which is the basis of this research.
Aim:
To establish the correlation between an individual’s innate unique constitution and specific biochemical indicators.
Materials and Methods:
The innate unique constitution of individuals was determined using electronic data, and the
relationships between their characteristics and levels of uric acid, creatinine, urea, and glucose in the blood were analyzed.
Results:
A total of 102 participants were included in the study. Among them, the Shar-Khi constitution was the most prevalent, with 28 cases (27.45%), while the Khi-Badgan constitution was the least common, with 13 cases (12.75%). Individuals with the Khi-Shar constitution exhibited the highest urea level at 4.47 ммоль/л, whereas those with the Badgan-Shar
constitution had the lowest at 4.15 ммоль/л. The uric acid level was highest in individuals with the Shar-Khi constitution
at 316.15 µmol/L and lowest in those with the Badgan-Shar constitution at 261.36 µmol/L (p<0.001).
Furthermore, individuals with the Badgan-Khi constitution had the highest creatinine level at 73.51 µmol/L, while those
with the Badgan-Shar constitution had the lowest at 63.97 µmol/L (p<0.001). The blood glucose level was highest in
individuals with the Khi-Badgan constitution at 4.59 ммоль/л and lowest in those with the Khi-Shar constitution at 4.21
ммоль/л. Kidney function indicators, particularly creatinine, significantly correlated with blood glucose levels (r=0.67,
p<0.01). Higher uric acid and creatinine levels were associated with elevated blood glucose levels. These findings suggest
that variations in urea, uric acid, and creatinine levels among different unique constitutions could be utilized to predict
the risk of kidney disease or diabetes.
Conclusion
Depending on the individual characteristics of traditional medicine, kidney and blood sugar parameters
are different and related to each other, and can assess the state of diabetes and kidney disease. Determining the inherent
characteristics of an individual is considered important for improving the diagnosis, treatment, and prevention of diabetes
and kidney disease.