1.Kilovoltage radiotherapy for companion animals: dosimetric comparison of 300 kV, 450 kV, and 6 MV X-ray beams
Jaehyeon SEO ; Jaeman SON ; Yeona CHO ; Nohwon PARK ; Dong Wook KIM ; Jinsung KIM ; Myonggeun YOON
Journal of Veterinary Science 2018;19(4):550-556
Radiotherapy for the treatment of cancer in companion animals is currently administered by using megavoltage X-ray machines. Because these machines are expensive, most animal hospitals do not perform radiotherapy. This study evaluated the ability of relatively inexpensive kilovoltage X-ray machines to treat companion animals. A simulation study based on a commercial treatment-planning system was performed for tumors of the brain (non-infectious meningoencephalitis), nasal cavity (malignant nasal tumors), forefoot (malignant muscular tumors), and abdomen (malignant intestinal tumors). The results of kilovoltage (300 kV and 450 kV) and megavoltage (6 MV) X-ray beams were compared. Whereas the 300 kV and 6 MV X-ray beams provided optimal radiation dose homogeneity and conformity, respectively, for brain tumors, the 6 MV X-rays provided optimal homogeneity and radiation conformity for nasal cavity, forefoot, and abdominal tumors. Although megavoltage X-ray beams provided better radiation dose distribution in most treated animals, the differences between megavoltage and kilovoltage X-ray beams were relatively small. The similar therapeutic effects of the kilovoltage and 6 MV X-ray beams suggest that kilovoltage X-ray beams may be effective alternatives to megavoltage X-ray beams in treating cancers in companion animals.
Abdomen
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Animals
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Brain
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Brain Neoplasms
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Friends
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Hospitals, Animal
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Humans
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Nasal Cavity
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Pets
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Radiotherapy
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Therapeutic Uses
2.Echocardiographic assessment of coronary artery flow in normal canines and model dogs with myocardial infarction.
Nohwon PARK ; Jaehwan KIM ; Miyoung LEE ; Soyun LEE ; Sunhye SONG ; Seungjun LEE ; Soyoung KIM ; Yangwoo PARK ; Kidong EOM
Journal of Veterinary Science 2014;15(1):149-155
This study was conducted to evaluate the usefulness of coronary arterial profiles from normal dogs (11 animals) and canines (six dogs) with experimental myocardial infarction (MI) induced by ligation of the left coronary artery (LCA). Blood velocity of the LCA and right coronary artery (RCA) were evaluated following transthoracic pulsed-wave Doppler echocardiography. The LCA was observed as an infundibular shape, located adjacent to the sinus of Valsalva. The RCA appeared as a tubular structure located 12 o'clock relative to the aorta. In normal dogs, the LCA and RCA mean peak diastolic velocities were 20.84 +/- 3.24 and 19.47 +/- 2.67 cm/sec, respectively. The LCA and RCA mean diastolic deceleration times were 0.91 +/- 0.14 sec and 1.13 +/- 0.20 sec, respectively. In dogs with MI, the LCA had significantly (p < 0.01) lower peak velocities (14.82 +/- 1.61 cm/sec) than the RCA (31.61 +/- 2.34 cm/sec). The RCA had a significantly (p < 0.01) rapid diastolic deceleration time (0.71 +/- 0.06 sec) than that found in the LCA (1.02 +/- 0.22 sec) of MI dogs. In conclusion, these profiles may serve as a differential factor for evaluating cardiomyopathy in dogs.
Animals
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Blood Flow Velocity/*veterinary
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Coronary Vessels/surgery/*ultrasonography
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Dog Diseases/*diagnosis
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Dogs/*physiology
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Echocardiography, Doppler, Pulsed/standards/*veterinary
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Female
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Male
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Myocardial Infarction/diagnosis/*veterinary