1.Necrotizing Pneumonia and Empyema in an Immunocompetent Patient Caused by Nocardia cyriacigeorgica and Identified by 16S rRNA and secA1 Sequencing.
Changmin YI ; Min Jung KWON ; Chang Seok KI ; Nam Yong LEE ; Eun Jeong JOO ; Joon Sup YEOM ; Hee Yeon WOO ; Hyosoon PARK
Annals of Laboratory Medicine 2014;34(1):71-75
No abstract available.
Aged
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Bacterial Proteins/genetics
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Empyema/complications/diagnosis/*microbiology
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Humans
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Immunocompromised Host
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Male
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Nocardia/classification/*genetics/isolation & purification
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Phylogeny
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Pneumonia/complications/diagnosis/*microbiology
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Positron-Emission Tomography
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RNA, Ribosomal, 16S/analysis
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Sequence Analysis, DNA
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Tomography, X-Ray Computed
2.The First Case of Catheter-related Bloodstream Infection Caused by Nocardia farcinica.
Sang Taek HEO ; Kwan Soo KO ; Ki Tae KWON ; Seong Yeol RYU ; In Gyu BAE ; Won Sup OH ; Jae Hoon SONG ; Kyong Ran PECK
Journal of Korean Medical Science 2010;25(11):1665-1668
Nocardia farcinica is an emerging pathogen in immunocompromised hosts. Even though several species of Nocardia have been reported as causative pathogens of catheter-related blood stream infections (CRBSI), CRBSI caused by N. farcinica has not been reported. A 70-yr-old man with a tunneled central venous catheter (CVC) for home parenteral nutrition was admitted with fever for two days. Norcardia species was isolated from the blood through CVC and peripheral bloods and identified to N. farcinica by 16S rRNA and rpoB gene sequence analyses. This report emphasizes the rapid and correct identification of causative agents in infectious diseases in the selection of antimicrobial agents and the consideration of catheter removal.
Aged
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Bacterial Proteins/genetics/metabolism
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Blood/microbiology
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Catheter-Related Infections/*diagnosis/microbiology/nursing
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Catheterization, Central Venous/*adverse effects
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Humans
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Immunocompromised Host
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Male
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Nocardia/classification/genetics/*isolation & purification
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Nocardia Infections/*diagnosis
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Parenteral Nutrition/nursing
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Polymerase Chain Reaction
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RNA, Ribosomal, 16S/genetics/metabolism
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Sequence Analysis, DNA