1.Effect of capsaicin on murine lymphocyte functions and lymphoid tissue morphology.
June Chul LEE ; Yeong Min PARK
Immune Network 2001;1(3):203-212
No abstract available.
Capsaicin*
;
Lymphocytes*
;
Lymphoid Tissue*
2.Anterior Decompression Treatment in the Cervical Spine Injuries with Neurologic Deficits
Soon Taek JEONG ; Young June PARK
The Journal of the Korean Orthopaedic Association 1996;31(3):447-454
To evaluate the neurologic and functional improvement of anterior decompression and fusion in patients with cervical spin injury, the clinical records and x-rays of 17 patients who were treated at Gyeong-Sang National University Hospital between January 1989 and December 1993 were analyzed. The results were as follows 1. There were complete injuries of the cord in six cases, incomplete injuries in nine and nerve root injuries in two. All the patients were treated using anterior decompression and autogenous iliac bone graft with cervical plate fixation within 7 days after trauma. 2. The average time lapse from the operation to radiological union was 9.2 weeks(range;7–14 weeks). 3. The prognosis for neurologic recovery mainly depends on the severity of the initial neurologic status. The recoveries of neurologic deficit were complete in four cases, partial in ten and none in three. The motor index improved from 45.6 to 64.6 and the modified Barthel index was 71.2 points at the last follow-up. 4. The clinical results were excellent in nine cases, good in three, fair in two and poor in three. In conclusion, anterior decompression and fusion with bone graft and cervical plate provided early mobilization and rehabilitation, and improved neurological function in a considerable portion of the patient who had neurologic deficits after cervical spine injuries.
Decompression
;
Early Ambulation
;
Follow-Up Studies
;
Humans
;
Neurologic Manifestations
;
Prognosis
;
Rehabilitation
;
Spine
;
Transplants
3.The Importance of Smoking Definitions for the Study of Adolescent Smoking Behavior.
Journal of Korean Academy of Nursing 2006;36(4):612-620
PURPOSE: Smoking is the leading cause of death and smoking initiation rarely occurs after adolescence. Thus research on adolescent smoking is crucial. A consistent definition of smoking is important because inconsistent definitions make comparisons across studies an arduous task. Thus, the aim of the study was to suggest future research directions for smoking definitions after examining pitfalls in the literature. METHODS: In this study the literature on adolescent smoking in the U.S. and South Korea was examined, and three types of smoking definitions were identified. Limitations in the studies are identified and future research directions are suggested. RESULTS: In the U.S. literature, smoking definitions can be categorized into three groups: definitions based on stage models, smoking trajectories, and definitions derived from specific data. In the South Korean literature, various levels of smoking have not been differentiated. CONCLUSIONS: While the literature does not provide a definitive answer regarding the definition of smoking, it suggests three issues to consider for future research. First, multiple measures of smoking are more desirable than a one-time measure. Second, theory- or trajectory-based smoking definitions are more desirable than definitions derived from available data. Finally, regularity and amount of cigarette use should be incorporated in defining smoking behavior.
Adolescent
;
*Adolescent Behavior
;
Behavioral Research
;
*Health Knowledge, Attitudes, Practice
;
Humans
;
Korea
;
Models, Psychological
;
Motivation
;
Smoking/*prevention & control/*psychology
;
*Terminology as Topic
;
United States
4.Comparison of the Clinical Effects of the Different Ventilatory Care Strategies in the Neonates with Acute Respiratory Failure: High Flow Rate - Constant Flow Rate.
June Dong PARK ; Beyng Il KIM ; Jung Hwan CHOI
Journal of the Korean Society of Neonatology 1999;6(2):145-153
PURPOSE: High flow rate (FR) and pressure limit (PL) strategy with time-cycled pressure-limited (TCPL) ventilator is employed routinely in the neonates. Theoretical basis of this strategy is the two-compartment theory that the lung with acute respiratory failure consists of units with different compliance and resistance. But such constant pressure strategy has the risk of ventilator induced lung injury. We compared the ventilatory indices and clinical outcomes of two different strategies, high FR-constant pressure and low FR-constant FR in the ventilator care of the neonates with acute respiratory failure. METHODS: For the neonates born in our hospital and treated with mechanical ventilation from March to August in 1997, two different ventilator strategies were employed randomly with flow control ventilator. In the high-FR group, the FR was fixed at 10 L/ min and the PL was adjusted according to the arterial blood gas analysis (ABGA) results. In the low-FR group, the FR was adjusted to 10 mL/kg of tidal volume. Sixty neonates were enrolled, 32 in high-FR and 28 in low-FR group. Ventilatory indices and clinical outcomes were statistically cornpared in the two groups. RESULTS: Perinatal factors were not different in the two groups. Initial ventilator settings, ABGA results and ventilatory indices were not different. The tidal volume, fraction of inspired oxygen, peak inspired pressure and oxygenation index were higher and dynamic compliance was lower in the high-FR group compared to the low-FR group after 3 to 72 hours of ventilator care. In clinical outcomes, incidences of pulmonary interstitial emphysema, pneumothorax and chronic lung disease were significantly lower in the low-FR group. CONCLUSION: Low-FR with constant FR strategy resulted in better clinical outcomes in the ventilator care of neonates. We conclude that constant FR strategy prevents damage of the better compliant lung units and decreases the incidence of acute and chronic complications of ventilator care.
Blood Gas Analysis
;
Compliance
;
Emphysema
;
Humans
;
Incidence
;
Infant, Newborn*
;
Lung
;
Lung Diseases
;
Oxygen
;
Pneumothorax
;
Respiration, Artificial
;
Respiratory Insufficiency*
;
Tidal Volume
;
Ventilator-Induced Lung Injury
;
Ventilators, Mechanical
5.Infection Control Program in Yonsei Medical Center.
Eun Suk PARK ; Young Suk KIM ; June Myung KIM
Korean Journal of Nosocomial Infection Control 1999;4(1):51-57
No Abstract available.
Infection Control*
6.A Simple Storage and Retrieval System for Pathologic Diagnoses Using the Apple II(R) Computer.
Sang Sook LEE ; Chi Hwan LEE ; June Sik PARK
Korean Journal of Pathology 1986;20(2):184-186
The coding and filing of pathologic diagnoses have been heavy tasks; however with the availability of inexpensive microcomputer, a system may be developed that permits storage and retrieval to be performed efficiently. With Apple II(R) computer system and SNOP coding, a simple program using dBASE-II and QUICKCODE computer program can be created to include the following informations: accession number, chart number, sex and age of patients and 2 diagnosis codes. Once SNOP coding is carried out by medical staff, a secretary or clerk can enter the informations into the microcomputer. Data may be searched on any combination of the above parameters.
7.Effect of low dose ethanol on experimental hepatocarcinogenesis.
Sang Chul PARK ; Sahng June KWAK ; Kye Yong SONG
Journal of the Korean Cancer Association 1991;23(2):161-168
No abstract available.
Ethanol*
8.Effect of Psychosocial Work Environment and Self-efficacy on Mental Health of Office Workers.
Kyung Ja JUNE ; Eun Suk CHOI ; Mi Jin PARK
Korean Journal of Occupational Health Nursing 2013;22(3):228-239
PURPOSE: This study aims to assess the effects of psychosocial work environment and self-efficacy on stress, depression, and burn-out among office workers. METHODS: Survey data were collected from 331 office workers who worked in one workplace from April 10 to 30, 2012. The impact of psychosocial work environment and self-efficacy on stress, depression, and burn-out was analyzed with hierarchical multiple regression using SAS version 9.3. RESULTS: Work-family conflicts and emotional demands were identified as main factors influencing mental health. Other work environment factors influencing mental health were role clarity for stress, possibilities for development, meaning-of work, social support-from supervisors and job insecurity for depression, and social community at work for burn-out. Self-efficacy was correlated with most psychosocial work environment and factor with independent influence on stress and depression. The final models including general characteristics, psychosocial work environment, and self-efficacy accounted for 34%, 44%, and 36% for stress, depression, and burn-out respectively. CONCLUSION: To promote mental health in office workers, there is a need to decrease work-family conflicts and emotional demands and to improve work organization and job contents, social support, and self-efficacy.
Depression
;
Mental Health
;
Social Work
9.Femoral lengthening and deformity correction by the ilizarov method.
Hui Wan PARK ; Jun Seop JAHNG ; Soo Bong HAHN ; Byeong Mun PARK ; Young June PARK
The Journal of the Korean Orthopaedic Association 1993;28(6):2206-2214
No abstract available.
Congenital Abnormalities*
;
Ilizarov Technique*
10.Expression of Surfactant-D Protein and TNF-alpha in the Interaction of Pneumocystis Carinii and Alveolar Macrophages in Pneumocystis Carinii Pneumonia.
Kun Young KWON ; Kwan Kyu PARK ; Chang Kwon PARK ; Young June JEON ; Eun Sook CHANG
Korean Journal of Pathology 1999;33(9):684-694
Alveolar macrophages participate in the host defense against P. carinii, but the mechanisms in degradation and clearance of the organism from lung has not been well established. We observed the transmission and scanning electron microscopic features and evaluated the expression of TNF-alpha and Surfactant-D in the interaction of P. carinii with alveolar macrophages. Expression of TNF-alpha and Surfactant-D in the experimentally induced P. carinii pneumonia in rat was examined by immunohistochemistry and immunoelectron microscopy. Electron microscopically, the alveolar macrophages phagocytized trophozoites and cysts of P. carinii micro-organisms. Immunohistochemically TNF-alpha was strongly expressed in the cytoplasms of alveolar macrophages. Postembedding immunogold labeling for Surfactant-D protein was expressed on the pellicles of trophozoites and cysts, P. carinii micro-organisms in the cytoplasms of macrophages, free floating surfactant materials and multilamellar bodies of type II epithelial cells. We conclude that alveolar macrophages interacted with P. carinii micro-organisms respond with increased expression of TNF-alpha. TNF-alpha may bind to P. carinii and exert a direct toxic effect upon the micro-organisms. Surfactant-D protein may augment binding of P. carinii to the alveolar macrophages and enhance the clearance of the micro-organisms.
Animals
;
Cytoplasm
;
Epithelial Cells
;
Immunohistochemistry
;
Lung
;
Macrophages
;
Macrophages, Alveolar*
;
Microscopy, Immunoelectron
;
Pneumocystis carinii*
;
Pneumocystis*
;
Pneumonia
;
Pneumonia, Pneumocystis*
;
Rats
;
Trophozoites
;
Tumor Necrosis Factor-alpha*