The effect of radiation therapy, either alone or combined with surgery or chemotherapy is accepted well in the treatment of metastatic carcinoma, multiple myeloma, reticulum cell sarcoma and Ewing's sarcoma. But its effect on osteosarcoma and chondrosarcoma is less clear. The authors reviewed 90 patients treated with radiation therapy, 62 cases with primary bone tumor and 28 cases with multiple myeloma, from 1969 to 1988. There were 20 Ewing's sarcoma, 12 osteosarcoma, 12 chondrosarcoma, 9 Histiocytosis-X and 3 reticulum cell sarcoma among 62 primary bone tumors. And 40 patients with more than three months follow-up were analyzed for the primary response of tumor three months after radiation therapy and the long term effect of the radiation therapy. When the radiation therapy was done alone, the primary response was poor in osteogenic sarcoma, chondrosarcoma, Ewing's sarcoma and reticulum cell sarcoma. But with the multimodal therapy, the primary response was rslatively good in reticulum cell sarcoma and chondrosarcoma. In 15 patients, more than one year follow-up was done. The status of these patients at the last follow-up was poor in all cases trearted with radiation therapy alone than the multimodal therapy except Histiocytosis-X. In multiple myeloma, the effect of radiation therapy for the relief of pain was analyzed. There were complete relief of pain in 14.3%, partial relief in 71.4% and no relief in 10.7%.
Chondrosarcoma ; Drug Therapy ; Follow-Up Studies ; Histiocytosis, Langerhans-Cell ; Humans ; Lymphoma, Non-Hodgkin ; Multiple Myeloma ; Osteosarcoma ; Sarcoma, Ewing

The antihypertensive effect of Minizide(0.5mg prazosin hydrochloride and 0.25mg polythiazide per tablet)was evaluated in 30 patients with essential hypertension with a dosage of one tablet a day for four weeks. The results were as follows : 1) Of 30 patients treated with Minizide, 21 patients(70.0%) achieved normalization of blood pressure and 5 patients(16.7%) had good response. 2) Mean drop in systolic and diastolic pressure were 29.0mmHg and 15.9mmHg respectively in supine position(P<0.005). 3) Mean drop in systolic and diastolic pressure were 28.5mmHg and 16.2mmhg respectively in sitting position(P<0.005). 4) In 14 patients(46.7%) among 30 patients treated with Minizide adverse reactions developed. The most frequent one was postural dizziness(23.3%). 5) Most adverse reactions were transient and tolerable. However, in three patients(two patients with postural dizziness and one patient with dry mouth) the medication was stopped due to adverse reactions.
Blood Pressure ; Dizziness ; Humans ; Hypertension ; Polythiazide ; Prazosin

No abstract available

Cigarette smoke is a complex mixture of 4,000 chemical compounds, including 43 known carcinogens. It is well known that smoke acts as the initiator and promoter in the process of carcinogenesis, and the risk of cancer is directly proportional to the amount and duration of smoking. Tobacco is the cause of 30% of all cancer deaths and one of the major risk factors for coronary heart disease, along with high blood pressure and hyperlipidemia. Cigarette smoking is estimated to be responsible for more than 20% of all coronary heart disease deaths in men over 86 years of age and for approximately 45% of such deaths in men aged less than 65 years. About 80% of mortality from chronic obstructive lung disease is attributable to cigarette smoking, and the age-adjusted death rate for COPD is 10-times higher in current smokers than in nonsmokers. Peptic ulcer disease, osteoporosis, skin wrinkling, and retarded fetal growth are all associated with cigarette smoking. Through passive smoking, 69% of individuals develop eye irritation, 29% have nasal symptoms, 32% have headaches, and 25% develop a cough. The infant admission rate increases with mother’s smoking amount, and the relative risk of lung cancer is 1.8 in smoker’s spouse. Tobacco is the single, chief, avoidable cause of death in our society, and the most important public issue of our time.
Carcinogenesis ; Carcinogens ; Cause of Death ; Coronary Disease ; Cough ; Fetal Development ; Headache ; Humans ; Hyperlipidemias ; Hypertension ; Infant ; Lung Neoplasms ; Male ; Mortality ; Osteoporosis ; Peptic Ulcer ; Pulmonary Disease, Chronic Obstructive ; Risk Factors ; Skin Aging ; Smoke ; Smoking* ; Spouses ; Tobacco ; Tobacco Products* ; Tobacco Smoke Pollution

No abstract available.
Maxillary Sinus* ; Wegener Granulomatosis*

No abstract available.
Antigens, Human Platelet* ; Blood Platelets*

No abstract available.

This study was conducted to evaluate the differences of scores in overall health-promoting behavior between residents in the Seoul area and rural inhabitants : and to examine the relationship between socio-demographic characteristics and the level of practical performance of the six dimension subscales of the Health-Promoting Lifestyles Profile (HPLP). Data were collected by questionnaire survey over a period of 2 months from July 1st to August 31st, 1997. Subjects chosen for this study consisted of 170 individuals, including 85 Seoul dwellers and 85 rural occupants in Korea. These were sampled from the Seoul and the local adult populations, using a random sampling method. However, the actual number of subjects put into the analyses was 151, including 68 Seoul residents and 83 rural inhabitants. Data were analysed by the SAS program. Statistical methods employed for this study were frequency, t-test, one/two-way ANOVA and MANOVA. The results were as follows : 1. It was revealed that there was a statistically significant difference between Seoul dwellers and rural inhabitants in the scores of health promoting life style activities, that is, Seoul area and rural inhabitants ; and to examine the relationship between socio-demographic characteristics and the level of practical performance of the six dimension subscales of the Health-Promoting Lifestyles Profile (HPLP). Data were collected by questionnaire survey over a period of 2 months from July 1st August 31st, 1997. Subjects chosen for this study consisted of 170 individuals, including 85 Seoul dwellers and 85 rural occupants in Korea. These were sampled from the Seoul and the local adult populations, using a random sampling method. However, the actual number of subjects put into the analyses was 151, including 68 Seoul residents and 83 rural inhabitants. Data were analysed by the SAS program. Statistical methods employed for this study were frequency, t-test, one/two-way ANOVA and MANOVA. The results were as follows : 1. It was revealed that there was a statistically significant difference between Seoul dwellers and rural inhabitants in the scores of health promoting life style activities, that is, Seoul occupants had higher scores in overall health promoting life styles than did the local residents. 2. The male population showed higher scores in overall health promoting life styles including self-actualization, health responsibility, interpersonal support and stress management than did the female. 3. The middle aged group (40-49 year old) showed higher scores in overall health promoting life styles than any other age group. 4. The married sample showed higher scores in health responsibility and nutrition than did the unmarried, the divorced, or the widowee/widower. The scores were almost the same between the married and the unmarried group, even though the unmarried group had slightly higher scores in self-actualization, exercise, interpersonal support, and stress management of the HPLP than did the married. 5. Public officials and clerical workers showed higher scores in overall health promoting lifestyles than did the others including house wives, farmers, business-men, or professionals. But in the analysis of mutual interactions of both age and occupation, business-men, merchants, public officials and clerical workers in 40-49 years of age with their health responsibility showed higher scores in overall health promoting lifestyles than did the others, while professionals showed lower scores relatively. While professionals showed lower scores relatively. 6. A person who earned over 1,500,000 Won as a monthly income showed higher scores in overall health promoting life styles than the person who earned under 1,500,000 Won, 7. A statistical significance was not found in the difference between the socio-demographic variables, such as levels of education and HPLP scores in overall health promoting life styles. These findings differed from the existing previous study's results in which the higher educational levels contributed to the health promoting behaviors. Therefore, the author suggested that the level of formal education can not playn and important role in the practical performance of health promoting behaviors, at present, because of the more effective community-based health education through the mass media such as TV and video.
Adult ; Divorce ; Education ; Female ; Health Education ; Humans ; Korea* ; Life Style* ; Male ; Mass Media ; Middle Aged ; Occupations ; Seoul ; Single Person ; Spouses ; Surveys and Questionnaires

No abstract available.
Osteoarthritis*

Dementia as a public health problem looms as an epidemic of the 21st century. The aging population places an increasing number of individuals at risk for dementia. It is predicted that the proportion of the population over 65 years will exceed 14% by 2022 in Korea. This paper aims at summarizing epidemiologic characteristics of dementia in the general population in Korea, which are essential to develop a preventive strategy to this dreadful disease. The prevalence of dementia has been estimated in several studies in Korea and was found to be around 9.5 to 13.0% among individuals aged 65 years and over, which appears a little higher than those reported in other countries. According to the etiologic subtypes, more than half of the cases are reported to be Alzheimer's disease (AD) in most studies, especially in studies conducted in rural areas. These results are similar to those reported in the western countries, with AD being more common. In Asia, it was expected that vascular dementia would be much more common than AD due to the high prevalence of cerebrovascular accidents. Women have a much higher prevalence rate than men in all studies, presumably due to the higher prevalence of AD among the oldest aged 80 and over. These phenomena may be related with the high rate of illiteracy and low level of education among women in this country. Further epidemiologic studies on the subtype and risk factors of dementia are necessary to develop a comprehensive strategy for prevention of this disease in Korea.
Aging ; Alzheimer Disease ; Asia ; Dementia* ; Dementia, Vascular ; Education ; Epidemiologic Studies ; Epidemiology* ; Female ; Humans ; Korea* ; Literacy ; Male ; Prevalence ; Public Health ; Risk Factors ; Stroke