No abstract available.
Diabetic Retinopathy* ; Retina*

No Abstract Available.
Central Serous Chorioretinopathy* ; Retina* ; Retinal Detachment* ; Retinaldehyde*

riie snbjects werc 269 patients with uncomplicated gonococcal urethritis, who visited the Veiereal Disease Clinic of Choong-Ku Public Health Center in Fieoul from August to Decernber 1984. ()ni hundred and four of 108 patients treated with 1.anamycin, 2 gm, IM plus anipi illin,3.5 gm, p0 plus probenecid, 1 gm, PO regirrien recovered with 65(62. 5 post-gonococcal urethritis(PGlJ) and 4(3.7%) failed, One hundred and seven of III patients treated with kanamycin, 2 gm, IM plus talarnpicillin, 2 gm, PO plus probenecid, 1 gm, po regimen recovered with 71 (66. 4% ) post-goriococcal urethritis and 4(3. 6%) failed. It is suggeste,d that both these antibiotic comlbination regimens have similarly good effect in the treatment. of gonococcal urethritis.
Ampicillin* ; Humans ; Kanamycin* ; Probenecid* ; Public Health ; Talampicillin* ; Urethritis

We reviewed charts of 148 patients(148 eyes) who were diagnosed with rhegmatogenous retinal detachment and operated from January 1994 to December 1995 and followed for at least 3 months postoperatively at kangnam St. Mary's hospital. We compared preoperative findings, surgical methods, ultimate anatomic success and visual outcome by macular involvement, and evaluated the causes of decrease in visual acuity after operation. Fifty four eyes were A group without involved macula and 94 eyes were B group with involved macula. There were no differences betwetm the two groups according to age, sex distribution, preoperative refractive error and location of retinal breaks. In the eyes with detached macular(B group), the duration and the extent of retinal detachment and the numbers of retinal breaks were more than those of A Group. Postoperatively 52 eyes(96.3%) with spared macular and 84 eyes(89.4%) with detached macular were anatomically reattached. Forty two eyes(77.8%) with spared macula achived visual acuity of 0.3 or better, in contrast to 2.5 eyes(26.6%) with detached macula. The most common causes of decrease in visual acuity after operation were proliferative vitreoretinopathy, macular pucker, cystoid macular edma and subretinal hemorrhage.
Hemorrhage ; Refractive Errors ; Retinal Detachment* ; Retinal Perforations ; Retinaldehyde* ; Sex Distribution ; Visual Acuity ; Vitreoretinopathy, Proliferative

Author performed this experiment to define the most important factor preventing the intimal thickening. An endothelium of abdominal aorta in the rat was denuded by two different wires having same caliver. The degree of injury was limited to the endothelial cells in one, and extended to the internal elastic lamina in another. The results showed that at 72 hours, in the case of superficial injury, the entire injury site was covered by new regenerating cells, but in the case of disruption of the internal elastic lamina, the migrating smooth muscle cell completely reached into the intima and resulted in intemal thickening. Similar findings persisted to 1 week later. Above results suggest the most important factor preventing the intimal thickening in endothelial injury is the depth of the injury which limited within the endothelial cells without extending into the internal elastic lamina and medial smooth muscle cells.
Rats ; Animals

Inspite of technical advances, long term retinal reattachment of proliferative vitreoretinopathy following the successful surgery is often disturbed by the occurrence of cell proliferation and traction. A variety of antimetabolite or anticancer drugs have been tried to use for testing their antiproliferative effects on proliferative vitreoretinopathy. To evaluate the antiproliferative property of 5-FU, we treated with the different concentration of 5-FU(0.5, 1, 5, 10 mg/L) on cultured bovine retinal pigment epithelial cells and performed dose inhibition studies. We also examined the 5-FU treated bovine retinal pigment epithelial cells by inverted microscope daily to evaluate the morphologic change for 5 days. The results were as follows; 1. 5-FU inhibited proliferation of bovine pigment epithelial cells in a dose dependent and a time dependent manner. 2. The drug concentration required for 50% inhibition of cell growth(ID50) was found to be 1.87 mg/L. 3. As the drug concentration increased, the cell density gradually decreased and the degenerative changes such as irregular shape of cells, cytoplasmic vaculoes and cell debris were aggravated. In 10 mg/L of 5-FU treated well, disruption of cell membrane and cell death were noted from the first day of incubation. These results show that 5-FU has a potent antiprolifertive effects in retinal pigment epithelial cell and toxic effet in high dose.
Cell Count ; Cell Death ; Cell Membrane ; Cell Proliferation ; Cytoplasm ; Epithelial Cells* ; Fluorouracil* ; Retinaldehyde* ; Traction ; Vitreoretinopathy, Proliferative

Aphakic or pseudophakic glau-oma is known to be at high risk for failure after filtration surgery. The authors retrospectively investigated the results of trabeculectomy in 14 eyes of 14 patients with glaucoma, seven aphakic and seven pseudophakic eyes, which were followed from six months to three years with an average ot 16.5 months. A conventional trabeculectomy without using antifibrotic agents was performed in all the eyes. The site of conjunctival incision was prepared on the virgin area of the conjunctiva; 8 superonasal, 4 inferonasal and 2 inferotemporal approaches. An average postoperative intraocular pressure reduction was 13.4 mmHg. The number of medications decreased in 11 eyes. A spontaneously developed functioning bleb was found in seven eyes. In other four eyes, the filtering bleb was formed with an aid of massage or needling. The remallllllg three eyes did not show a functioning bleb. Postoperative complications included hyphema in 3 eyes, overfiltration in 2 eyes, choroidal detachment in 1 eye, corneal edema in 1 eye and endophthalmitis in 1 eye.
Aphakia* ; Blister ; Choroid ; Conjunctiva ; Corneal Edema ; Endophthalmitis ; Filtering Surgery* ; Glaucoma ; Humans ; Hyphema ; Intraocular Pressure ; Massage ; Postoperative Complications ; Pseudophakia* ; Retrospective Studies ; Trabeculectomy

A statistical analysis of the diagnostic value for 244 aspiration biopsy cytology(ABC) among a total 1,043 cases from various sites was performed. ABC, using diagnostic terminology similar to that of a surgical pathology reports, was compared to the final tissue diagnosis. For the entire series, a sensitivity of 91.8%, a specificity of 99.3%, a positive predictive value of 98.9%, a negative predictive value of 94.8%, and an efficacy of the test of 96.3% were shown. There were 8 false negative and 1 false positive diagnosis. The diagnostic accuracy was 89.8%. Those results indicate that the ABC is a considerably highly accurate procedure that should be routinely employed.
Biopsy, Needle ; Child* ; Diagnosis ; Glomerulonephritis, IGA* ; Humans ; Immunoglobulin A* ; Intranuclear Inclusion Bodies ; Meningioma ; Pathology, Surgical ; Sensitivity and Specificity

Seventy-six patients who visited Kang-Nam St. Mary's Hospital with keratoconus from 1982 to 1987 were reviewed retrospectively. At the time of diagnosis, the age-specific prevalence were greatest in the younger groups, with the rate for males being somewhat greater than that for females and the rate of bilateral involvement was greater than that of unilateral involvement. Of 126 eyes with. keratoconus, 76 achieved visual acuity of 0.3 or better with hard contact lens at the time of diagnosis. Thirty-nine received corneal graft and 38(97%) achieved visual acuity of 0.3 or better with correction. Keratoplasty can be delayed or avoided in many keratoconus patients by using contact lens, especially the specially designed lenses. Also keratoconus eyes often need contact lenses after keratoplasty.
Contact Lenses ; Corneal Transplantation ; Diagnosis ; Female ; Humans ; Keratoconus ; Keratoplasty, Penetrating ; Male ; Prevalence ; Retrospective Studies ; Transplants ; Visual Acuity

Seventy-six patients who visited Kang-Nam St. Mary's Hospital with keratoconus from 1982 to 1987 were reviewed retrospectively. At the time of diagnosis, the age-specific prevalence were greatest in the younger groups, with the rate for males being somewhat greater than that for females and the rate of bilateral involvement was greater than that of unilateral involvement. Of 126 eyes with. keratoconus, 76 achieved visual acuity of 0.3 or better with hard contact lens at the time of diagnosis. Thirty-nine received corneal graft and 38(97%) achieved visual acuity of 0.3 or better with correction. Keratoplasty can be delayed or avoided in many keratoconus patients by using contact lens, especially the specially designed lenses. Also keratoconus eyes often need contact lenses after keratoplasty.
Contact Lenses ; Corneal Transplantation ; Diagnosis ; Female ; Humans ; Keratoconus ; Keratoplasty, Penetrating ; Male ; Prevalence ; Retrospective Studies ; Transplants ; Visual Acuity