1.Angiogenesis of Retina in Diabetic Retinopathy.
Journal of Korean Society of Endocrinology 2001;16(3):339-351
No abstract available.
Diabetic Retinopathy*
;
Retina*
2.Measurement and Analysis of Neurosensory Retinal Detachment in Central Serous Chorioretinopathy Using Heidelberg Retina Tomograph.
Jae Yong HEO ; No Hoon KWAK ; Jin Seong YOO
Journal of the Korean Ophthalmological Society 2000;41(12):2585-2590
No Abstract Available.
Central Serous Chorioretinopathy*
;
Retina*
;
Retinal Detachment*
;
Retinaldehyde*
3.Tre atment of Gonorrhoea with Antibiotic Combinations : Kanamycin plus Ampicillin / Probenecid versus Kanamycin plus Talampicillin / Probenecid.
Chang Hoon KWAK ; Jae Hong KIM ; Joong Hwan KIM
Korean Journal of Dermatology 1985;23(6):745-751
riie snbjects werc 269 patients with uncomplicated gonococcal urethritis, who visited the Veiereal Disease Clinic of Choong-Ku Public Health Center in Fieoul from August to Decernber 1984. ()ni hundred and four of 108 patients treated with 1.anamycin, 2 gm, IM plus anipi illin,3.5 gm, p0 plus probenecid, 1 gm, PO regirrien recovered with 65(62. 5 post-gonococcal urethritis(PGlJ) and 4(3.7%) failed, One hundred and seven of III patients treated with kanamycin, 2 gm, IM plus talarnpicillin, 2 gm, PO plus probenecid, 1 gm, po regimen recovered with 71 (66. 4% ) post-goriococcal urethritis and 4(3. 6%) failed. It is suggeste,d that both these antibiotic comlbination regimens have similarly good effect in the treatment. of gonococcal urethritis.
Ampicillin*
;
Humans
;
Kanamycin*
;
Probenecid*
;
Public Health
;
Talampicillin*
;
Urethritis
4.A Clinical Study on Rhegmatogenous Retinal Detachment by Macular Involvement.
Yong Kwan KWAK ; No Hoon KWAK ; Warne HUH
Journal of the Korean Ophthalmological Society 1996;37(10):1688-1693
We reviewed charts of 148 patients(148 eyes) who were diagnosed with rhegmatogenous retinal detachment and operated from January 1994 to December 1995 and followed for at least 3 months postoperatively at kangnam St. Mary's hospital. We compared preoperative findings, surgical methods, ultimate anatomic success and visual outcome by macular involvement, and evaluated the causes of decrease in visual acuity after operation. Fifty four eyes were A group without involved macula and 94 eyes were B group with involved macula. There were no differences betwetm the two groups according to age, sex distribution, preoperative refractive error and location of retinal breaks. In the eyes with detached macular(B group), the duration and the extent of retinal detachment and the numbers of retinal breaks were more than those of A Group. Postoperatively 52 eyes(96.3%) with spared macular and 84 eyes(89.4%) with detached macular were anatomically reattached. Forty two eyes(77.8%) with spared macula achived visual acuity of 0.3 or better, in contrast to 2.5 eyes(26.6%) with detached macula. The most common causes of decrease in visual acuity after operation were proliferative vitreoretinopathy, macular pucker, cystoid macular edma and subretinal hemorrhage.
Hemorrhage
;
Refractive Errors
;
Retinal Detachment*
;
Retinal Perforations
;
Retinaldehyde*
;
Sex Distribution
;
Visual Acuity
;
Vitreoretinopathy, Proliferative
5.Abnormal Brain CT Findings of Tuberous Sclerosis.
Young Suck RO ; Chang Hoon KWAK ; Jae Hong KIM ; Joong Hwan KIM ; Gi Chul HAN
Korean Journal of Dermatology 1985;23(1):77-82
The lesions of central nervous system in tuberous sclerosis often calcify, especially those present in the perivascular region, allowing the computed tomography to make early and definite diagnosis, even when patients intelligence was normal, seizures were absent, or clinical findings were not specific, We report three cases of tuberous sclerosis, which showed pathognomic subependymal paraventricular calcification in brain CT.
Brain*
;
Central Nervous System
;
Diagnosis
;
Humans
;
Intelligence
;
Seizures
;
Tuberous Sclerosis*
6.Pulmonary Infiltration in Rotaviral Gastroenteritis.
Wan Sup KWAK ; Wang Bock LEE ; Haeng Mi KIM ; Ja Hoon KOO
Journal of the Korean Pediatric Society 1985;28(5):448-454
No abstract available.
Gastroenteritis*
7.Clinical Evaluation of Kefatoconus.
No Hoon KWAK ; Man Soo KIM ; Jae Ho KIM
Journal of the Korean Ophthalmological Society 1989;30(3):351-356
Seventy-six patients who visited Kang-Nam St. Mary's Hospital with keratoconus from 1982 to 1987 were reviewed retrospectively. At the time of diagnosis, the age-specific prevalence were greatest in the younger groups, with the rate for males being somewhat greater than that for females and the rate of bilateral involvement was greater than that of unilateral involvement. Of 126 eyes with. keratoconus, 76 achieved visual acuity of 0.3 or better with hard contact lens at the time of diagnosis. Thirty-nine received corneal graft and 38(97%) achieved visual acuity of 0.3 or better with correction. Keratoplasty can be delayed or avoided in many keratoconus patients by using contact lens, especially the specially designed lenses. Also keratoconus eyes often need contact lenses after keratoplasty.
Contact Lenses
;
Corneal Transplantation
;
Diagnosis
;
Female
;
Humans
;
Keratoconus
;
Keratoplasty, Penetrating
;
Male
;
Prevalence
;
Retrospective Studies
;
Transplants
;
Visual Acuity
8.Clinical Evaluation of Kefatoconus.
No Hoon KWAK ; Man Soo KIM ; Jae Ho KIM
Journal of the Korean Ophthalmological Society 1989;30(3):351-356
Seventy-six patients who visited Kang-Nam St. Mary's Hospital with keratoconus from 1982 to 1987 were reviewed retrospectively. At the time of diagnosis, the age-specific prevalence were greatest in the younger groups, with the rate for males being somewhat greater than that for females and the rate of bilateral involvement was greater than that of unilateral involvement. Of 126 eyes with. keratoconus, 76 achieved visual acuity of 0.3 or better with hard contact lens at the time of diagnosis. Thirty-nine received corneal graft and 38(97%) achieved visual acuity of 0.3 or better with correction. Keratoplasty can be delayed or avoided in many keratoconus patients by using contact lens, especially the specially designed lenses. Also keratoconus eyes often need contact lenses after keratoplasty.
Contact Lenses
;
Corneal Transplantation
;
Diagnosis
;
Female
;
Humans
;
Keratoconus
;
Keratoplasty, Penetrating
;
Male
;
Prevalence
;
Retrospective Studies
;
Transplants
;
Visual Acuity
9.Comparison of the Effect of Cefadroxil and Kanamycin Sulfate in the Treatment of Male Gonorrhoea.
Chang Hoon KWAK ; Young Suck RO ; Young Tae KIM ; Jae Hong KIM ; Joong Hwan KIM
Korean Journal of Dermatology 1984;22(6):599-603
No abstract available.
Cefadroxil*
;
Humans
;
Kanamycin*
;
Male*
10.Effects of 5-fluorouracil on culture of Bovine Retinal Pigment Epithelial cells.
No Hoon KWAK ; Jin Seong YOO ; Warne HUH
Journal of the Korean Ophthalmological Society 1995;36(3):466-472
Inspite of technical advances, long term retinal reattachment of proliferative vitreoretinopathy following the successful surgery is often disturbed by the occurrence of cell proliferation and traction. A variety of antimetabolite or anticancer drugs have been tried to use for testing their antiproliferative effects on proliferative vitreoretinopathy. To evaluate the antiproliferative property of 5-FU, we treated with the different concentration of 5-FU(0.5, 1, 5, 10 mg/L) on cultured bovine retinal pigment epithelial cells and performed dose inhibition studies. We also examined the 5-FU treated bovine retinal pigment epithelial cells by inverted microscope daily to evaluate the morphologic change for 5 days. The results were as follows; 1. 5-FU inhibited proliferation of bovine pigment epithelial cells in a dose dependent and a time dependent manner. 2. The drug concentration required for 50% inhibition of cell growth(ID50) was found to be 1.87 mg/L. 3. As the drug concentration increased, the cell density gradually decreased and the degenerative changes such as irregular shape of cells, cytoplasmic vaculoes and cell debris were aggravated. In 10 mg/L of 5-FU treated well, disruption of cell membrane and cell death were noted from the first day of incubation. These results show that 5-FU has a potent antiprolifertive effects in retinal pigment epithelial cell and toxic effet in high dose.
Cell Count
;
Cell Death
;
Cell Membrane
;
Cell Proliferation
;
Cytoplasm
;
Epithelial Cells*
;
Fluorouracil*
;
Retinaldehyde*
;
Traction
;
Vitreoretinopathy, Proliferative