1.RADIATION ACCIDENT IN 1963 AND 18 YEARS FOLLOW-UP OF THE 4 SURVIVED CASES
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
In 1963, we treated 6 cases of acute radiation sickness (200-8,000 rad) resulted from an accidental uneven 60Co ?-ray irradiation; two of them died of intestinal type within two weeks. Four cases survived and one of them recovered from septicemic shock. Loss of hair, systemic infection, high fever and bleeding occurred in 5 patients. The essential therapeutic measures were strict isolation, preventive treatment with antiinfection drugs, fresh blood transfusion and sometimes infusion of blood formed elements. Among the survivals 2 received homologous bone marrow transplantation.The general conditions of 4 patients followed up for a period of 18 years are apparently good with transparent lens, normal thyroid function and immunological reactions, except one who had low serum IgG level. Three of them showed subnormal adrenocortical activity and impairment of sex gland function. A girl patient (400 rad) gave birth to 2 children one of which has retarded intellectual development. Serial EEG changes occurred only in those received high cranial doses. In all the cases persistence of chromosome aberration in peripheral lymphocytes was observed. With high doses (above 10,000 rad) remote regional effects led to amputation of one leg in one patient and pathological fracture of the femur in another.
2.THE EFFECT OF THE COMBINATION OF MEXILETINE AND PROPRANOLOL ON VENTRICLE EXTRASYSTOLE
Chinese Pharmacological Bulletin 1987;0(01):-
A combination of Mexiletine and propranolol was administered in 40'patients suffering from ventricle extrasystole. The results suggest that the effect of the combination is superior to that of mexiletine administered alone
3.The effects of oxygen free radicals on hyperoxia induced-damages of rabbit aortic endothelial cell
Hai-Tao YUAN ; Niu TIAN ;
Chinese Journal of Pathophysiology 1986;0(04):-
The changes of morphology, ATP and malonaldehyde (MDA) contents, xanthine oxidase (XO) activity as well as the glutathione peroxidase (GSH-px) activity of rabbit aortic endothelial cells under hyperoxia (100% O_2) for 0-72 hours were studied. We found that cellular morphological changes including swelling, shape variation after hyperoxia were time-dependent; after a temporarily increasing (24hr)(P
5.Effect of ANH and autologous transfusion on the onset-duration-recovery profile of pipecuronium
Xinhuan NIU ; Yuke TIAN ; Zhijun CHEN
Chinese Journal of Anesthesiology 1997;0(11):-
35%.The patients were premedicated with intramuscular phenobarbital 0.1g and atropine 0.5 mg. In group B and C 8-12 ml?kg-1 of blood was withdrawn from cubital vein in 10-15 min and equal volume of 6% hydroxyethyl was infused at the same speed simultaneously before anesthesia. In group C the blood shed during operation was collected and anticoagulated for reinfusion. Anesthesia was induced with fentanyl 4-6?g?kg-1 , propofol 2 mg?kg-1 and pipecuronium 0.1 mg?kg-1.The patients were mechanically ventilated after tracheal intubation and PETCO2 was maintained at 25-35 mm Hg. Anesthesia was maintained with 1%-3% isoflurane and intermittent iv boluses of fentanyl and pipecuronium. Lactated Ringer's solution was infused at 10-12 ml?kg-1.h-1 during operation in all patients. ECG, NIBP, SpO2, PETCO2 and CVP were monitored throughout anesthesia. Plasma protein, Hct and Hb were measured before and after ANH and after reinfusion of the shed blood. Neuromuscular function was assessed using a train-of-four stimulation (TOF). Onset time, peak effect time (when T1 decreased to 0), duration of action (from the end of pipecuronium injection to recovery of T1 to 25% of the control) of intubation dose and maintenance dose and recovery index (recovery of T1 from 25 % - 75%) were recorded.Results Demographic data including sex, age, body weight and height were not significantly different among the three groups. The vital signs were stable in the three groups. Plasma total protein and albumin concentrations, Hb and Hct decreased significantly after ANH in group B and C and were significantly lower than those in group A. After autologous transfusion there was no significant difference in plasma protein concentration and Hb between group A and B. Hb and Hct were significantly higher in group C than those in group A and B (P
6.C_3 POLYMORPHISM IN CHINESE POPULATION IN SHAANXI
Mingzhan XUE ; Xiaohong NIU ; Tian LIN
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(01):-
273 chinese have been studied with high voltage electrophoresis and immumofixation to survey the polymorphism of the third component of human complement in Shaanxi Provice Two C_3 phenotypes were found in this population, they are C_3SS and C_3FS The frequencies of C_3SS and C_3FS are 98.53% and 1.47% respectively. The frequency of C_3S gene is 0.9926 and C_3F gene 0.0073. These results are similar to other studies in China and this group was in Hardy-Weinberg equilibrium. Compared with Negro and Caucasian, the chinese population in Shaanxi Province has a significant difference in C_3 polymorphism.
7.Parents' attitude toward children with disabilities learning in regular class
Yubai NIU ; Zewen LIU ; Bao TIAN
Chinese Journal of Rehabilitation Theory and Practice 2005;11(1):72-73
Objective To investigate the parents' attitude toward the handicapped children learning in regular class.MethodsThe Questionnaire of the Parents' Attitude Toward Learning in Regular Class was used to measure the attitude of 240 parents of handicapped children and 480 of normal children. ResultsThe attitude of parents of handicapped children was much more positive than that of parents of normal children. The attitude of parents of deaf children is much more positive than that of parents of mental retarded (MR) children. The attitude of parents of normal children who were studying with the deaf children was much more positive than that of parents of normal children who were studying with the MR children. There was no significant difference among parents of different education levels, occupation and sex. ConclusionHandicapped children learning in regular class need more attention from parents.
8.Parents' attitude inventory for handicapped children learning in regular class
Yubai NIU ; Zewen LIU ; Bao TIAN
Chinese Journal of Rehabilitation Theory and Practice 2005;11(2):154-156
ObjectiveTo workout a scale of parents' attitude towards handicapped children learning in regular class.MethodsQuestionnaire on the parents' attitude toward learning in regular class was designed and administered to 240 parents of handicapped children and 480 parents of normal children.ResultsThe questionnaire was consisted of 34 valid items and proved to be a reliable and valid instrument.ConclusionThis questionnaire is an innovation on testing attribute to some limitation, but the normal formulation has to be depended on future study.
9.The value of Tei index for evaluation on chronic heart failure
Jing LIN ; Ming KONG ; Haomiao SUN ; Xiaohong TIAN ; Wenjuan NIU
Chinese Journal of Primary Medicine and Pharmacy 2013;20(14):2161-2162
Objective To explor the value of Tei index for evaluation the cardiac function of patients with chronic heart failure(CHF).Methods Tei index in 60 patients with CHF(CHF group) and 30 normal controls(control group) were evaluated and compared with the levels of NT-ProBNP and the NYHA class,and the sensitivity and specificity of Tei index for CHF diagnosis were appraised.Results (1) Tei index in CHF group was significantly higher than that in control group.When Tei index was more than and equal to 0.45,the sensitivity,specificity,positive predictive value,and negative predictive value of Tei index for diagnosing CHF were 85.6%,90.4%,89.8% and 78.0%.(2)There was a remarkable positive correlation between Tei and Log NT-ProBNP(r =0.84,P < 0.01).(3)There were significant differences in Tei index among NYHA Ⅱ,Ⅲ,Ⅳ class [(0.47 ± 0.06),(0.56 ± 0.08),(0.64 ±0.13)].Conclusion Tei index can be used to diagnose CHF and evaluate the degree of it.
10.The method of hole drainage surgery in clinical for the treatment of stable subdural hematoma
Zhihe TAO ; Shaobin TIAN ; Jinsong CHEN ; Hongquan NIU
Chinese Journal of Postgraduates of Medicine 2013;36(z1):15-16
Objective Investigate the effective treatment for the stable subdural hematoma.Methods About the patients need for surgical treatment,for the treatment of hole drainage surgery,and according to the retrospective to be analyzed.Results The 68 cases of patients with surgical indications,under local anesthesia to surgery with the method of hole drainage surgery,achieve the desired results and objectives.Conclusions The hole drainage surgery is a simple way,and little chance of complications.As long as select the appropriate cases,during the surgery with standardized operation and at the end of surgery use standardized management,select the method of hole drainage surgery to treat the stable subdural hematoma is feasibility.