1.Dermoid cyst in the floor of the mouth
Jagadish H. Chandra ; Priyanka K Shetty, ; Veena K. M. ; Nitin Gonsalves
Pacific Journal of Medical Sciences 2017;17(1):61-65
Dermoid cysts are rare developmental benign lesions that arise as a result of ectodermal differentiation of multipotent cells. Histologically the cysts are classified as dermoid, epidermoid and teratoid cysts depending on the presence of adnexal structures and derivatives of germ layers. When dermoid cysts appear in the floor of the mouth they can cause difficulty in deglutition and respiration. The differential diagnosis of dermoid cyst could be infection, ranulaor tumor. Intraoral or extra oral approach for enucleation is the method of treatment. Dermoid cysts have a good prognosis with low malignancy and recurrence rate. A case report of a dermoid cyst in the floor of the mouth is presented in this paper along with clinical, histopathological evaluation and the treatment.
2.Impact of post-hepatectomy biliary leaks on long-term survival in different liver tumors:A single institute experience
Devesh Sanjeev BALLAL ; Shraddha PATKAR ; Aditya KUNTE ; Sridhar SUNDARAM ; Nitin SHETTY ; Kunal GALA ; Suyash KULKARNI ; Mahesh GOEL
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(4):451-457
Background:
s/Aims: A postoperative biliary leak is one of the most morbid complications occurring after a liver resection, the longterm impact of which remains unknown.
Methods:
Retrospective analysis of consecutive liver resections performed from 1 January 2011 to 31 December 2021. Primary endpoint of disease-free survival (DFS) was compared between patients with and without a bile leak, stratifying for tumor type. Survival curves were plotted using Kaplan–Meier estimates, and differences between them were analyzed using the log–rank test.
Results:
In toto, 862 patients were analyzed, and included 306 (35.5%) hepatocellular carcinomas, 212 (24.6%) metastatic colorectal cancers, and 111 (12.9%) cholangiocarcinomas (69 intrahepatic cholangiocarcinomas, 42 hilar cholangiocarcinomas). Occurrence of a bile leak was associated with significantly poorer DFS only in patients with cholangiocarcinoma (median DFS 9.9 months vs. 24.9 months, p = 0.013), and further analysis was restricted to this cohort. A Cox regression performed for factors associated with DFS detriment in patients with cholangiocarcinoma showed that apart from node positivity (hazard ratio [HR]: 2.482, p = 0.033) and margin positivity (HR: 2.65, p = 0.021), development of a bile leak was independently associated with worsening DFS on both univariate and multiple regression analyses (HR: 1.896, p = 0.033).
Conclusions
Post-hepatectomy biliary leaks are associated with significantly poorer DFS only in patients with cholangiocarcinoma, but not in patients with hepatocellular carcinoma or metastatic colorectal cancer. Methods to mitigate this survival detriment need to be explored.
3.Impact of post-hepatectomy biliary leaks on long-term survival in different liver tumors:A single institute experience
Devesh Sanjeev BALLAL ; Shraddha PATKAR ; Aditya KUNTE ; Sridhar SUNDARAM ; Nitin SHETTY ; Kunal GALA ; Suyash KULKARNI ; Mahesh GOEL
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(4):451-457
Background:
s/Aims: A postoperative biliary leak is one of the most morbid complications occurring after a liver resection, the longterm impact of which remains unknown.
Methods:
Retrospective analysis of consecutive liver resections performed from 1 January 2011 to 31 December 2021. Primary endpoint of disease-free survival (DFS) was compared between patients with and without a bile leak, stratifying for tumor type. Survival curves were plotted using Kaplan–Meier estimates, and differences between them were analyzed using the log–rank test.
Results:
In toto, 862 patients were analyzed, and included 306 (35.5%) hepatocellular carcinomas, 212 (24.6%) metastatic colorectal cancers, and 111 (12.9%) cholangiocarcinomas (69 intrahepatic cholangiocarcinomas, 42 hilar cholangiocarcinomas). Occurrence of a bile leak was associated with significantly poorer DFS only in patients with cholangiocarcinoma (median DFS 9.9 months vs. 24.9 months, p = 0.013), and further analysis was restricted to this cohort. A Cox regression performed for factors associated with DFS detriment in patients with cholangiocarcinoma showed that apart from node positivity (hazard ratio [HR]: 2.482, p = 0.033) and margin positivity (HR: 2.65, p = 0.021), development of a bile leak was independently associated with worsening DFS on both univariate and multiple regression analyses (HR: 1.896, p = 0.033).
Conclusions
Post-hepatectomy biliary leaks are associated with significantly poorer DFS only in patients with cholangiocarcinoma, but not in patients with hepatocellular carcinoma or metastatic colorectal cancer. Methods to mitigate this survival detriment need to be explored.
4.Impact of post-hepatectomy biliary leaks on long-term survival in different liver tumors:A single institute experience
Devesh Sanjeev BALLAL ; Shraddha PATKAR ; Aditya KUNTE ; Sridhar SUNDARAM ; Nitin SHETTY ; Kunal GALA ; Suyash KULKARNI ; Mahesh GOEL
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(4):451-457
Background:
s/Aims: A postoperative biliary leak is one of the most morbid complications occurring after a liver resection, the longterm impact of which remains unknown.
Methods:
Retrospective analysis of consecutive liver resections performed from 1 January 2011 to 31 December 2021. Primary endpoint of disease-free survival (DFS) was compared between patients with and without a bile leak, stratifying for tumor type. Survival curves were plotted using Kaplan–Meier estimates, and differences between them were analyzed using the log–rank test.
Results:
In toto, 862 patients were analyzed, and included 306 (35.5%) hepatocellular carcinomas, 212 (24.6%) metastatic colorectal cancers, and 111 (12.9%) cholangiocarcinomas (69 intrahepatic cholangiocarcinomas, 42 hilar cholangiocarcinomas). Occurrence of a bile leak was associated with significantly poorer DFS only in patients with cholangiocarcinoma (median DFS 9.9 months vs. 24.9 months, p = 0.013), and further analysis was restricted to this cohort. A Cox regression performed for factors associated with DFS detriment in patients with cholangiocarcinoma showed that apart from node positivity (hazard ratio [HR]: 2.482, p = 0.033) and margin positivity (HR: 2.65, p = 0.021), development of a bile leak was independently associated with worsening DFS on both univariate and multiple regression analyses (HR: 1.896, p = 0.033).
Conclusions
Post-hepatectomy biliary leaks are associated with significantly poorer DFS only in patients with cholangiocarcinoma, but not in patients with hepatocellular carcinoma or metastatic colorectal cancer. Methods to mitigate this survival detriment need to be explored.
5.A comparative analysis of distal locked and unlocked long proximal femoral nail antirotation (PFNA-II) in the fixation of stable intertrochanteric fractures.
Atmananda HEGDE ; Vikrant KHANNA ; Prajwal MANE ; Chethan SHETTY ; Nitin JOSEPH
Chinese Journal of Traumatology 2023;26(2):111-115
PURPOSE:
Long proximal femoral nail anti-rotation (PFNA-II) is a preferred implant in recent years for fixation of pertrochanteric fractures, especially in osteoporotic patients. The purpose of this study is to prospectively investigate the effect of distal locking in long PFNA-II fixation of stable intertrochanteric fractures.
METHODS:
A total of 58 patients with isolated stable intertrochanteric fractures and treated in our hospital during the study period of 2017-2019 by distal locked or unlocked long PFNA-II fixation were included in this study. Patients who had multiple injuries or open fractures were excluded. There were 40 female and 18 male patients, with 33 affecting the left side and 25 the right side. Of them, 31 belonged to the distal locked group (group A) and 27 to the unlocked group (group B). Surgical procedures and implants used in both groups were similar except for the distal locking of the nails. General data (age, gender, fracture side, etc.) showed no significant difference between two groups (all p > 0.05). The intraoperative parameters like operative time, radiation exposure and follow-up parameters like functional and radiological outcomes were recorded and compared. Statistical tests like the independent samples t-test Fischer's exact and Chi-square test were used to analyze association.
RESULTS:
The distribution of the fractures according to AO/OTA classification and 31A1.2 type of intertrochanteric fractures were most common in our study. All the included fractures united and the average functional outcome in both groups were good and comparable at the end of one year. The operative time (mL, 107.1 ± 12.6 vs. 77.0 ± 12.0, p < 0.001) and radiation exposure (s, 78.6 ± 11.0 vs. 40.3 ± 9.3, p < 0.001) were significantly less among the patients in group B. Fracture consolidation, three months after the operative procedures, was seen in a significantly greater proportion of patients in group B (92.6% vs. 67.7%, p = 0.025). Hardware irritation because of distal locking bolt was exclusively seen in group A, however this was not statistically significant (p = 0.241).
CONCLUSION
We conclude that, in fixation of stable intertrochanteric fractures by long PFNA-II nail, distal locking not only increases the operative time and radiation exposure but also delays the fracture consolidation and increases the chances of hardware irritation, and hence is not required.
Humans
;
Male
;
Female
;
Fracture Fixation, Intramedullary/methods*
;
Bone Nails
;
Treatment Outcome
;
Retrospective Studies
;
Hip Fractures/etiology*
;
Femoral Fractures/etiology*
6.Preoperative estimation of humerus intramedullary nail length using clinical landmarks.
Atmananda S HEGDE ; Chethan B SHETTY ; Nitin JOSEPH ; Prajwal MANE ; Samarth THAKKAR
Chinese Journal of Traumatology 2023;26(5):256-260
PURPOSE:
Intramedullary interlocking nailing is one of the accepted methods of treating humerus diaphyseal fractures. Appropriate nail length and diameter are of paramount importance to achieve a stable fracture fixation. Estimating the nail length can be as challenging in certain cases as it is important. This study aims to provide an easy-to-use formula utilizing clinical measurements from contra lateral arm to accurately estimate humeral nail length.
METHODS:
This descriptive cross-sectional study was conducted at 3 tertiary care hospitals in Mangalore, India. Patients above the age of 18 years coming to the outpatient department with elbow, shoulder or arm complaints requiring radiological investigation from July 2021 to July 2022 were included. Patients with fractures or dislocations of upper limbs, malunited or non-united fractures of upper limbs, congenital or developmental deformities and patients with open growth plates were excluded. Patients' variables (like age and gender), radiological humerus length and contralateral arm clinical measurements were recorded. An independent samples t-test was used for univariate analysis, and linear regression analysis was done to estimate the desired nail length using the clinical measurement of the humerus (cm) in both genders separately. The significance level was set at p < 0.05.
RESULTS:
Our study included 204 participants of which 108 were male and 96 were female. The formula for predicting humeral nail length in males is (-2.029) + (0.883 × clinical measurement). The formula for females is 1.862 + (0.741 × clinical measurement). A simplified formula to determine humeral nail length is 0.9 clinical length - 2 cm (in males) and 0.7 × clinical length + 2 cm (in females).
CONCLUSION
To improve the stability of fixation with intramedullary nails it is imperative to select the appropriate nail length. There have been studies that devised reliable methods of determining nail lengths in the tibia and femur using preoperative clinical measurements. A similar clinical method of determining humeral nail length is lacking in the literature. Our study was able to correlate radiological lengths of the humerus medullary canal with clinical measurements performed using anatomical landmarks to arrive at a formula. This allows for a reliable and easy nail length determination preoperatively.
Humans
;
Male
;
Female
;
Adolescent
;
Cross-Sectional Studies
;
Bone Nails
;
Humerus/surgery*
;
Fracture Fixation, Intramedullary/methods*
;
Humeral Fractures/surgery*
;
Treatment Outcome