1.The relationship of Type A behavior and defense style in doctors
Chinese Journal of Behavioral Medicine and Brain Science 2001;10(2):137-138
Objective To explore the relationship between Type A Behavior and Defense Style. Method 49 medical students and 34 doctors were investigated by the Defense Style Questionnaire (DSQ) and Type A Behavior Questionnaire (TABQ). Results Immature and middle defense styles were more used by Type A subjects than Type B and Type M subjects (P<0.05). TABQ total score was significantly associated with immature and middle defense styles (P<0.001 or P<0.05). Conclusion Immature and middle defense styles were associated with Type A Behavior.
2.Relationship between carotid arteries atherosclerosis and subclinical hypothyroidism in patients with type 2 diabetes mellitus
Ning YANG ; Yuan XU ; Donglei ZHANG
Chinese Journal of Postgraduates of Medicine 2013;(16):13-15
Objective To investigate the relationship between carotid arteries atherosclersis and subclinical hypothyroidism in patients with type 2 diabetes mellitus (T2DM).Methods From January to December 2010,408 patients with T2DM were enrolled in this study.The patients were divided into euthyroidism group (376 patients) and subclinical hypothyroidism group (32 patients).The incidence of carotid arteries atherosclerosis in two groups was compared and the risk factors were analyzed by Logistic regression analysis in patients with T2DM.Results There was no significant difference in age,course of disease,body mass index,fasting plasma glucose,total cholesterol,high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol,triacylglycerol and glycosylated hemoglobin between two groups (P > 0.05).The incidence of carotid arteries atherosclerosis in subclinical hypothyroidism group was higher than that in euthyroidism group [81.2% (26/32) vs.61.4% (231/376)],and the difference was significant (P =0.026).Logistic regression analysis showed that age and thyroid stimulating hormone (TSH)were risk factors (OR =1.178 and 1.227,P =0.000 and 0.019) and HDL-C was protective factor (OR =0.284,P =0.003) in T2DM with carotid arteries atherosclerosis.Conclusion Higher incidence of carotid arteries atherosclerosis is found in T2DM patients with subclinical hypothyroidism and increased TSH are independent risk factors that has not previously been described.
3.A study of platelet parameter changes in patients with Graves disease
Ning YANG ; Yuan XU ; Donglei ZHANG
Chinese Journal of Postgraduates of Medicine 2009;32(25):31-33
feature of GD that has not previously been described.
4.Endoscopic treatment of severe acute cholangitis accompanied with multiple organ dysfunction syndrome
Bo YANG ; Shuren MA ; Wenping ZHOU ; Xudong YUAN ; Ning ZHANG
Chinese Journal of Digestive Endoscopy 2009;26(11):565-567
Objective To evaluate the endoscopic managements of acute cholangitis of severe type (ACST) accompanied with multiple organ dysfunction syndrome (MODS). Methods A total of 122 ACST patients accompanied with MODS from January 2000 to October 2008 underwent endoscopic treatment in two time periods. In critical phase, emergent endoscopic retrograde cholangiopancreatography (ERCP) plus en-doscopic naso-biliary drainage (ENBD) were performed to correct critical situation of the patients. After sta-bilization, endoscopic sphincterotomy (EST) plus stone removal, EST plus stent placement, or laparoscopy was performed according to the causes of ACST. Results Emergent endoscopic managements succeeded in all patients of critical phase. At third day post-operation, a reduction in white blood cell count, serum total bilirubin, body temperature, and rate of patients with shock, mental symptoms and purulent bile juice was a-chieved. Recovery rate of dysfunction organs was 60.2% at one week after emergent procedure, and 82. 6% at 2 weeks post-operation. Selective EST plus stone removal was performed in 36 patients with a success rate n one session at 91.7%. Laparoscopic cholecystectomy was performed in 85 patients with a success rate of 95.3%. Stent was placed in 16 patients with an effective rate of 81.3% at 3 months post the procedure. No severe complication or death occurred during the whole therapeutic course. The 6-month survival rate of 10 cancer cases was 70%. Conclusion Therapeutic ERCP plus ENBD is the first choice for acute severe cholangitis accompanied with MODS, while EST plus biliary lithotomy, or EST plus stent placement, or com-bined laparoscopy are ideal methods for subsequent treatment.
5.CTA features of pure myocardial bridge on the patients without symptom
Mingyuan YUAN ; Huiqun ZHANG ; Rongxian LI ; Zhongping NING ; Xinming LI
Journal of Practical Radiology 2017;33(4):581-584
Objective To analyze the CTA features of asymptomatic myocardial bridge.Methods The CTA images of 69 cases with asymptomatic solitary myocardial bridge were studied retrospectively, and CTA images of 60 cases with symptoms as the contrast group.The type, age, thickness of myocardial bridge, mural coronary artery length and diameter changes of each cases of two groups were analyzed.Results In the study group, 51 cases of 69 (74%) were superficial style, while 18 cases were deep type (26%).In the contrast group, the superficial and deep style were 13 (22%) and 47 (78%) respectively.The mean age,thickness of myocardial bridge,mural coronary artery length and the diameter of mural coronary artery were (53.01±11.17) years old,(1.25±1.16) mm,(21.33±7.32) mm,(2.86±0.45) mm and (51.36±9.31) years old,(1.45±1.87) mm,(20.07±6.60) mm and (1.37±0.41) mm.The rate of type and diameter of mural coronary artery had significant differences between two groups (P<0.05), while other data had no significant differences (P>0.05).Conclusion The CTA features of asymptomatic myocardial bridge are mostly superficial type.The diameter of mural coronary artery on the end systolic is a factor to judge the rate on the occurrence of clinical symptom.
6.Effects of pioglitazone on angiotensin Ⅱ-induced proliferation and collagen expression of adventitial fibroblasts
jia, ZHANG ; ping-jin, GAO ; ning-yuan, FANG
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(09):-
Objective To investigate the effects of pioglitazone on angiotensin Ⅱ(AngⅡ) -induced proliferation and collagen typeⅠ expression of adventitial fibroblasts (AF). Methods The AFs were isolated from rat thoracic aorta. MTT colorimetry and flow cytometry were used to study the effects of pioglitazone on proliferation and cell cycles of AF. The expression of collagen typeⅠ regulated by pioglitazone was examined by the method of Western blot. Results Pioglitazone inhibited the proliferation of AF in a dose-dependent manner, and the most marked effect could be observed at the concentration of 10?10-6 mol/L for pioglitazone (P
7.Analysis and counter measures of working stress related factors of nurses in intensive care unit: report from three top hospitals in Beijing
Xiaohui ZHANG ; Ziwei DAI ; Yuan LI ; Bo NING
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2017;24(4):429-432
Objective To analyze the working stress related factors of nurses in intensive care unit (ICU), and put forward the corresponding counter measures.Methods During January to March 2016, a questionnaire survey was conducted with a commonly used nurses working pressure source scale on 110 ICU nurses in three People's Liberation Army (PLA) 3A grade hospitals in Beijing. The questionnaire survey involved 35 items within 5 main categories, including nursing professional issues, nursing workload and time allocation, working environment and resources, special care for critical patients and inter-personnel relationships between the head of nurses and other nurses. The correlations between the ICU nursing working stress and alternative factors were analyzed.Results Ninety-six nurses said the job was stressful, and 88.5% of them expressed that the degree of pressure was more than medium. The correlation analysis showed that ICU nurse working stress was correlated with 29 items in the survey scale (allP < 0.05), of which the top 6 items the mostly closely related were the frequent working shift (r = 0.58,P = 0.000), low nursing social status (r = 0.54,P = 0.000), less promotion opportunities (r = 0.54,P = 0.000), less opportunities to pursue further study (r = 0.53, P = 0.000), nurse low salary (r = 0.52,P = 0.000) and excessive workload (r= 0.50,P = 0.000).Conclusions ICU nurses face a lot of pressure in their work, the management departments should pay more attention to them, and actively energetically improve the nurse system construction, raise ICU nurses' pride, enhance the quality of nurse care and promote the healthy development of nursing profession.
8.Characteristics of Coronary CT Angiography in Patients With Myocardial Bridge Combining Arrhythmia
Mingyuan YUAN ; Huiqun ZHANG ; Rongxian LI ; Zhongping NING ; Xinming LI
Chinese Circulation Journal 2017;32(6):580-583
Objective: To study the characteristics of coronary CT angiography (CTA) in patients with myocardial bridge (MB) with arrhythmia. Methods: Our study included 2 groups: MB+arrhythmia group,n=31, clinical information as medical record, electrocardiogram (ECG), myocardial enzyme, echocardiography and coronary CTA findings were collected; MB group, n=30, the MB patients were without arrhythmia. Results: In MB+arrhythmia group, all patients were with mere MB, coronary artery disease, valve-structural heart diseases and other systemic diseases were excluded. There were 2/31 patients with ventricular fibrillation, 1 with atrial fibrillation, 5 with supraventricular tachycardia and 23 with ventricular tachycardia; 17/31 patients having deep type MB and 14 having superficial type MB. The myocardial systolic end diameter, diastolic end diameter by retrospective ECG gating and the stenosis at cross section of mural coronary MB by CTA were similar between 2 groups,P>0.05. Conclusion: MB+arrhythmia patients had no specific characteristics in coronary CTA; anatomical CTA feature may partly explain the myocardial ischemic symptom while couldn't clarify arrhythmia occurrence in relevant patients.
9.The treatment of papillary thyroid carcinoma located in the isthmus
Mengyi WANG ; Hongwei YUAN ; Ning ZHANG ; Yuewu LIU
Journal of Endocrine Surgery 2015;9(1):9-12
Objective To investigate the treatment for papillary thyroid carcinoma (PTC) located in the isthmus.Methods 90 patients with PTC located in the isthmus receiving surgery from May 2007 to Dec.2013 were enrolled.Patients' age,muhifocality,capsular invasion,central compartment lymph node metastasis were analyzed and compared with the results of 82 patients who had PTC within the thyroid lobe.Results In patients with PTC located in the isthmus,those with multi foci were older((49.4 ± 9.9)years,P =0.004).Patients with capsular invasion had larger tumor((1.02 ± 0.43) cm,P =0.001).Compared with PTC within the lobe,PTC located in isthmus were more likely to be multifocal (27.8% vs 14.6%,P =0.036)and capsular invasive(42.2% vs.19.5%,P =0.001).Central compartment lymph nodes metastasis rate was higher in patients with PTC located in isthmus but no statistical difference was found(53.3% vs 48.8%,P =0.551).Conclusions PTC located in the isthmus tends to be more aggressive at early stage.Central compartment lymph node metastasis occursearly and can be on both sides.Most patients should receive total thyroidectomy and central compartment lymph node dissection of both sides,but there's no need to dissect lymph node beneath the recurrent laryngeal nerve on the contralateral central compartment.
10.Clinical effects of tolterodine with pelvic floor electrical stimulation in the treatnent of female OAB patients
Ning LIU ; Chunlin LIU ; Chao FENG ; Jinsheng ZHANG ; Yuan QU
Clinical Medicine of China 2012;28(8):867-869
Objective To investigate whether tolterodine combined with pelvic floor electrical stimulation is more effective than tolterodine alone in the treatment of wonen with overactive bladder(OAB) and the underlying mechanism.Methods Seventy-three female patients with OAB were recruited from our hospital during Oct.2009 to Dec.2010 and prospectively studied,of whom 39 cases were given tolterodine(2 mg each time,twice daily for4 weeks)alone while the other 34 cases were given tolterodine combined with pelvic floor electrical stimulation for the treatment of OAB.Data on urgency,incontinence,micturition frequency,nocturia episodes and voided volume were collected before and after 4 weeks' treatment using a week micturition diary.Results The differences of changes of OAB symptoms between the 2 groups had statistical significance (P < 0.05).Patients in the tolterodine combined with pelvic floor electrical stimulation group reported treatment benefit than the tolterodine group in the micturitions and the volume voided per micturition(P < 0.05).There were no difference in the number of urgency episodes per 24 hours,incontinence episodes and nocturnal episodes (P > 0.05).Conclusion A combination of toterodine with pelvic floor electrical stimulation could significantly improve the OAB symptoms,and is a potential therapy for female patients with OAB.