Objective To evaluate the diagnostic value of CT enhanced scan and delayed CT scan in hepatic cholangiocarcinoma.Methods CT plain scan,enhanced CT scan and delayed CT scan were perfomed in 21 patients with hepatic cholangiocarcinoma pathollogically proved.Results The lesions were low density in all patients on plain CT,of them,14 patients were cystiform,7 cases were solid with intrahepatic biliary duct expansion within the lesions.Incomplete thin rim-like enhancement of the tumor periphery was seen on CT enhanced scan in 10 cases of 14 cystiform,complete enhancement in 3 cases.There was not any change in the 13 patients on portal venous phase,1 case didn't show enhancement,substantial tumors in 7 patients showed slightly enhancement after 1 minute of CT enhanced scan and delayed enhancement was seen after 3~8 minutes.The intrahepatic biliary duct expansion didn't change.The density of the tumor was equal to the liver of the same level or exceeded.Conclusion The complete or incomplete thin rim-like enhancement of the tumor of cystiform periphery on CT enhanced scan,not any change on portal venous phase or substantial tumors with intrahepatic biliary duct expansion in delayed enhancement are the characteristic signs of hepatic cholangiocarcinoma.

Nutrients have an important role in the progression of digestive tract cancer.The progress is regulated by the aberrant DNA,apoptosis,et al.This review is about the associated genes of methylation,nutrients,and molecular regulating mechanisms in esophageal cancer.

Objective To review outcomes in randomized controlled trials comparing labetalol with other anti hypertensives/placebo/no drug for mild to moderate hypertension in pregnancy.Methods We searched PubMed,China Knowledge Resource Integrated Database and VIP Database and performed a meta analysis of randomized controlled trials of labetalol for hypertension in pregnancy.Data were entered into RevMan software for analysis [relative risk (RR) and its 95％ confidence interval (CI)].Results Seven studies were included in the meta-analysis.Four trials (553 women) compared labetalol with methyldopa for mild to moderate hypertension in pregnancy.Labetalol reduced the risk of severe hypertension (RR=0.52,95％CI:0.31-0.88) and proteinuria (RR=0.57,95％CI:0.36 0.91).The incidence of preterm birth and small-for-gestational-age infants was similar between these two groups.Five trials (720 women) compared labetalol with placebo/no drug for mild to moderate hypertension in pregnancy.Labetalol reduced the risk of severe hypertension (RR=0.29,95％CI:0.16-0.53) and proteinuria (RR-0.73,95％CI:0.56-0.95) and showed no effect on preterm birth and small-for-gestational-age infants.Conclusions The results support the use of labetalol for mild to moderate hypertension in pregnancy.Labetalol is more effective in treating hypertension than methyldopa.However,due to the quality of the included studies,clinical effects of labetalol need to be evaluated in high quality randomized controlled trials.

Objective To analysisthe evaluation clinical effects and complications of retrograde peroneal artery perforators and retrograde posterior tibial artery fascia pedicle flap perforators fascia pedicle flap for the re-pair of the leg and foot skin defect effect. Methods In January 2010 to January 2015,patients with leg and foot skin defect effect in our hospital administrated withperoneal artery perforators and retrograde posterior tibial artery fascia pedicle flap perforators fascia pedicle skin flap were retrospectively analyzed.Flap survival,necrosis rate, the function of the skin flap and complications were analyzed. Results The one stage flap survival rate of peroneal artery group(84.6%)is higher than the posterior tibial artery group(57.69%),the difference was statistically sig-nificant(P < 0.05). There were no significant difference between the flap function index(pain,activity limita-tion,wearing shoes,functional recovery satisfaction)score and posterior tibial artery group(P>0.05). The occur-rence of hyperplastic scar,itching,pigmentation,skin graft,numbness,skin graft abnormal pain complication rates inperoneal artery group were significantly lower than the posterior tibial artery ,and the difference was statisti-cally significance(P < 0.05). Conclusion Retrograde peroneal artery perforators and retrograde posterior tibial artery fascia pedicle flap perforators fascia pedicle flap can effectively repair skin and soft tissue defect ,retrograde peroneal artery perforators shows with higher survival rate and less complication.

Carcinoma, Squamous Cell ; metabolism ; pathology ; Chemokine CCL2 ; metabolism ; Fibroblast Growth Factor 7 ; metabolism ; Fibroblasts ; metabolism ; pathology ; Gelatinases ; metabolism ; Humans ; Membrane Proteins ; metabolism ; Mouth Neoplasms ; metabolism ; pathology ; Neoplasm Invasiveness ; Neoplasm Metastasis ; Serine Endopeptidases ; metabolism

Arthralgia ; diagnosis ; etiology ; therapy ; Humans ; Medicine, Chinese Traditional ; Syndrome ; Tendon Injuries ; diagnosis ; therapy

Objective To understand the current status of advanced schistosomiasis patients, so as to provide the reference for improving the medical care of them in Shanggao County. Methods The data of advanced patients in Shanggao County were collected from the Information Management System for the Advanced Schistosomiasis Chemotherapy and Assistance in Jiangxi Province and a field survey including the epidemiological investigation physical examinations and B ultrasound examinations was performed in 2014. All the data were analyzed statistically and compared with those in 2010. Results Among the 128 ad?vanced schistosomiasis patients the male female ratio was 2.46 1 the average age was 68.02±6.19 years and the patients old?er than 65 years contributed to 64.84%for the all. The proportions of clinically types of ascites splenomegaly multiple granulo?ma in the colon dwarf general and haemorrhage were 57.81% 12.50% 2.34% 0 26.57% and 0.78% respectively. The ultrasound examinations revealed the average diameter of the main trunk of portal vein was 12.70 ± 1.91mm in 2014 which was significantly broader than that of 12.05 ± 0.34mm in 2010 P < 0.01 . Conclusions The advanced schistosomiasis patents in Shanggao County decreases with years and shows an aging trend. Some advanced schistosomiasis patients are worse therefore the chemotherapy and salvation work still should be strengthened.

Twenty days after the operation of anterior cervical decompression fusion with internal fixation, the fistula was found at the lower end of right neck incision with purulent secretion, the intumescent mucosa was founded at the posterior wall of the esophagus, down about 5 cm of the oesophagostomum. The metal plate sample exposed under the intumescent mucosa. The diagnosed was "neck esophageal fistula".
Decompression, Surgical ; Esophageal Fistula ; surgery ; Humans ; Neck

Objective To investigate lead pollution of drinking water stagnated in household pipe and its characteristic, and provide the scientific basis for safe and health consumption of drinking water. Methods 30 taps in households were randomly chosen as objects. According to the stagnated time the water samples were divided into group A (12-13 hours), group B (7-8 hours) and group C (3-4 hours). The samples were collected in 0 min, 1 min and 2 min after opening taps. Lead levels in the samples were determined by atomic absorption spectrometry (AAS), whose comparative analysis was performed by SPSS software. In total, 320 samples were analyzed. Results In group A, lead concentrations (geometric mean, the same for latter) of water samples in 0 min, 1 min and 2 min were 61.33, 12.27and 5.47 ?g/L respectively, but they were 33.90, 9.13 and 4.59 ?g/L in group B,and 11.37, 6.29 and 4.27 ?g/L in group C. There were significant differences among three groups (P