Objective : To investigate the willingness to receive HIV testing in primary health service institutions (PHSIs) among young students in Wuhan City, so as to provide the evidence for improving the detection of HIV testing among young students. Methods: Fifteen PHSIs were sampled using a stratified random sampling method in 14 districts of Wuhan City, and school students at ages of 15 to 24 years were sampled from each district using a convenience sampling method. Participants' demographics, awareness of AIDS-related knowledge, HIV testing and willingness to receive HIV testing were collected using questionnaires, and factors affecting the willingness to receive HIV testing in PHSIs were identified among school students using a multivariable logistic regression model. Results : A total of 301 questionnaires were allocated, and 299 valid questionnaires were recovered, with an effective recovery rate of 99.34%. The respondents included 143 men (47.83%) and 156 women (52.17%), and had a mean age of (19.36±2.40) years; there were 223 respondents with an educational level of diploma and above (74.58%). The awareness of AIDS-related knowledge was 71.57% among the respondents, and 144 respondents had received AIDS-related health education in PHSIs (48.16%). There were 34 respondents that had received HIV testing (11.37%) and 203 respondents that were willing to receive HIV testing in PHSIs (67.89%). The respondents that were unwilling to receive HIV testing in PHSIs were mainly attributed to considering to be unlikely to get HIV infections (82.29%). Multivariable logistic regression analysis showed that school students who knew AIDS-related knowledge (OR=2.797, 95%CI: 1.583-4.941), knew free HIV counseling and testing services in PHSIs (OR=2.070, 95%CI: 1.123-3.814), and had received AIDS-related health education in PHSIs (OR=2.814, 95%CI: 1.573-5.032) were more willing to receive HIV testing in PHSIs. Conclusions There were 67.89% of school students that were willing to receive HIV testing in PHSIs in Wuhan City, and the willingness to receive HIV testing was correlated with the awareness of risk of HIV infections, and awareness and experience of AIDS control services in PHSIs.

Objective:To investigate the relationship between urate deposition on ultrasound and coronary artery calcification score in maintenance hemodialysis (MHD) patients.Methods:A total of 100 stable MHD patients undergoing hemodialysis for at least one year were enrolled in this study. All the patients had clinical and ultrasound examination at both knees, ankles and first metatarsophalangeal joints. Subgroup analysis was done depending on whether double contour sign (DCS) or tophus was found on ultrasound. The volume of coronary artery calcification (CAC) score were determined by a 64-slice CT. Main statistical analysis methods were t test, chi-square test, Spearman correlation and logistic regression model. Results:Among these 100 patients, DCS was found in 35 (35%) patients and tophus was found in 21 (21%) patients. The serum uric acid level, serum phosphate (P), parathyroid hormone (PTH), C-reactive protein (CRP) and incidence of CAC, CAC score of the DCS positive group [(629±61) μmol/L, (2.4±0.8) mmol/L, (658±56) pg/ml, (9.5±2.1) mg/L, 83%(29/35), (276±37), n=35] was significantly higher than the DCS negative group [(569±68) μmol/L, (2.0±0.6) mmol/L, (536±49) pg/ml, (7.9±3.1) mg/L, 59% (38/65), (219±42), n=65] ( t=4.322 6, P<0.01; t=2.712 6, P<0.01; t=11.293 1, P<0.01; t=2.700 3, P<0.01; t=5.070 1, P=0.024 3; t=6.827 6, P<0.01). The serum uric acid level was positively correlated with urate deposition on ultrasound ( r=0.317, P<0.05), which was positively correlated with CAC score ( r=0.302, P<0.05). The serum uric acid level, urate deposition on ultrasound and CAC score were all positively correlated with CRP ( r=0.298, P<0.05; r=0.345 , P<0.05; r=0.336, P<0.05) . Multivariate logistic regression analysis showed that the serum uric acid level and CRP were independent risk factors for positive DCS in MHD patients [ OR=3.040, 95% CI (1.507, 6.133); OR=3.438, 95% CI(1.822,6.489)]. Positive DCS and CRP were independent risk factors for CAC [ OR=3.504, 95% CI (1.414, 9.684); OR=3.885, 95% CI(1.364, 11.063)]. Conclusion:In MHD patients, positive DCS is related with high serum uric acid level and CRP. Positive DCS and CRP are independent risk factors for CAC.

Objective:To evaluate the reliability and validity of the Reward Probability Index-Chinese version (C-RPI) among individuals with opioid dependence.Methods:A total of 160 individuals with opioid dependence were recruited from the methadone maintenance treatment(MMT) programs in Wuhan.The C-RPI was used in the investigation, and items/exploratory factors and confirmatory factors were adopted to analyze with IBM SPSS 22.0 and AMOS 24.0, respectively.Results:The correlation between each item and the total score of the scale was 0.325-0.657 (all P<0.01) and the item discrimination of the scale was good.Exploratory factor analysis extracted two factors, including reward probability and environmental suppressors, and a load of each item on its factor ranged from 0.519 to 0.744.The fitting indexes of confirmatory factor analysis were as follows: χ 2/ df=1.623, RMR=0.030, RMSEA=0.063, IFI=0.902, TLI=0.885, CFI =0.900.The internal consistency coefficient (Cronbach's α) of the C-RPI was 0.800; and there was no ceiling/floor effect on each dimension and total scale. Conclusion:The classification of dimensions for the C-RPI is reasonable, and the scale has good reliability and validity to measure the ability to obtain environmental rewards for individuals with opioid dependence.