This paper presents a preparation method and quality control standards of Hungqiduotang Granules. Meanwhile, the experiment result of primary studys on its preparation stability shows that the process and prescription is simple and reasonale, and the stability of granules is good.

Object To optimize the best technical parameters through controlling the different factors. Methods Taking spherical degree and pill weight as index, the above factors were observed by orthogonal test. Results PEG4000 as matrix, methyl silicon oil as refrigerant. Internal and external diameter of burette are 4 1 mm and 6 1 mm, dropping into the refrigerant that composed of 40 ℃—50 ℃,10 ℃—30 ℃,0 ℃—4 ℃ by 20 ℃—30 ℃ droppings per minute. Conclusion The highest finished product with good quality can be got through this process.

The content, range, mode and method of medical equipment management were explained by associating hospi- tal actuality. The value of scientific management can be directed and improved economic benefit and social effect too, which are an important construction of hospital efficiency.

Aimed at problems in current audio-visual-oral English teaching for medical students,such as the inconsistency between teaching materials and training objectives,the lack of flexibility and effectiveness in teaching methods and inadequacy of comprehensiveness and objectiveness in assessment methods,the paper analyses and explores audio-visual-oral medical English teaching in three aspects,namely teaching curriculum-setting up topic for each unit based on the contents of medical courses and designing various teaching tasks according to three-step procedure of extensive listening-intensive listening-derivative discussion,teaching methods-adopting pictorial method in teaching medical English vocabulary,macro-micro listening method and interpretation for imitation method,and assessment methods-applying a combination of formative assessment and summative assessment.

There has been great progress in seizure control with the development of antiepileptic drugs,but 30％ of epileptic children are refractory to antiepileptic drugs.In order to control intractable epilepsy and improve neurodevelopment prognosis,the non-drug therapy such as surgery,vagus nerve stimulation and ketogenic diet (KD) can be taken.Despite its indisputable effectiveness,the functioning of the KD has not been explained.Now the antiepileptic mechanism and neuroprotective mechanisms are studied mainly.It is reported that KD is effective in variety of refractory epilepsy,and recent studies have shown that KD promising in the treatment of children with autism.Although KD is effective,it is worth further study that including its mechanism,recipe,clinical application,and so on.

Cell Line, Tumor ; Cell Proliferation ; drug effects ; Flow Cytometry ; methods ; Humans ; Point Mutation ; Stomach Neoplasms ; genetics ; pathology ; Tumor Suppressor Protein p53 ; genetics ; pharmacology

Humans ; Laryngeal Diseases ; prevention & control ; Larynx ; Pharyngeal Diseases ; prevention & control ; Pharynx ; Pulmonary Disease, Chronic Obstructive ; prevention & control

Objective To investigate the effects of leptin on the oxidative damage in human retinal pigment epithelial (RPE) cells.Methods Human RPE cells (ARPE-19) were cultured in vitro,and randomly divided into control group and insulin resistance group.RPE cells were treated with 0,10,100 ng/mL leptin for 24,48,72 hours respectively.Then the levels of reactive oxygen species (ROS) expression in RPE cells were detected by 2',7'-dichlorofluorescin-diacetate (DCFH-DA),and the levels of 8-hydroxy-2′-deoxyguanosine (8-OHdG) expression in RPE cells were observed by immunocytochemistry (ICC),and the levels of human 8-oxoguanine DNA glycosylase 1 (hOGG1) expression in lysate were measured by Western blot.Results After 24,48,72 hours,the level of ROS (Control group:F=37.136,37.178,49.634; P＜0.05.Insulin resistance group:F=9.822,28.881,71.150;P＜0.05),8-OHdG (Control group:F =88.643,390.920,1039.276; P ＜ 0.05.Insulin resistance group:F =273.311,299.155,82.237;P＜0.05) and hOGGl (Control group:F=470.062,1073.113,295.456;P＜0.05.Insulin resistance group:F =240.032,592.389,527.760 ; P＜0.05) expression increased significantly with the increase of leptin concentration in control group and insulin resistance group.Under the same leptin concentration,the level of 8-OHdG has a trend that it was higher in the insulin resistance group than the control group.After 24 hours,the difference of hOGGl expression between control group and insulin resistance group was not significant (F=23.392,P＞0.05).After 72 hours,the level of hOGGl expression was significantly higher in the insulin resistance group than the control group (F=129.394,P＜0.05).The level of hOGGl expression was significantly higher at 48 hours than that at 24 hours and 72 hours (P＜ 0.05).Conclusion Leptin could induce the oxidative damage of RPE cells in normal and insulin resistance status.With the increase of leptin concentration and time extended,the degree of oxidative damage and its repair were both increased.The degree of oxidative repair increased with the increase of leptin concentration,but decreased with time extended.

Objective:To investigate the therapeutic effect of Chinese medicine combined with small dose of antidepressant on prospermia.Methods:150 cases of prospermia conformed to the diagnostic criteria were divided into 3 groups according to their wishes,50 cases in each group.Group I were treated with Zhibai Gujing Decoction,group Ⅱ with Sertraline hydrochloride,and group Ⅲ with Zhibai Gujing Decoction plus Sertraline hydrochloride,for 4 consecutive weeks.The ejaculatory latency,satisfaction degrees of sexual life,and the adverse effect of the medicine were observed.Results:After treatment,the ejaculatory latency was significantly prolonged and the satisfaction degree of sexual life was significantly increased in the 3 groups(P

Objective To establish the quality standard for Zhilining pill. Methods TLC was employed to identify Radix Sophorae Flavescentis and Radix Aucklandiae while the content of dehydroandrographolide in Zhilining pill was detemined by HPLC. Results TLC findings of Radix Sophorae Flavescentis and Radix Aucklandiae showed the spots of same colors as those developed in the corresponding places of control medical materials. Good liner was observed when the samplesize of dehydroandrographolide was within the range of 0.062～1.550 ?g (r =1.000 0). The average recovery rate was 98.00% with RSD=0.90%. Conclusion The method is simple, accurate, stable, reliable and with good reproducibility, which can be used for the quality control of Zhilining pill.