1.Electrolyte disorder in heart failure patients
Journal of Practical Medicine 2003;450(4):57-59
At Cho Ray Hospital – Ho Chi Minh city from Dec 2001 to Dec 2002, 228 heart failure cases (96 males, 130 females, aged 58.4317.45) were studied. Their associated conditions were: 14 with diabetes, 5 brain blood infactus, 5 hyperthyroidies, 19 kidney failures. Among 162 patients with electrolyte disorders, 25 were died, the rate of hyponatremia and hyperkalemia was significantly higher in fatal group than in survival group. Hyponatremia was fatal risk factor and it should pay great attention to treat this condition with hypertonic natrium solution
Heart Failure, Congestive
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Cardiovascular Diseases
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Patients
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Electrolytes
2.Results of medical arthropod surveys in the natural conserve zone- Can Gio mangrove forests, Ho Chi Minh city
Chau Van Nguyen ; Hien Thi Do ; Kha Thi Nguyen ; Bich Xuan Phung ; Lien Thi Bich Nguyen ; Binh Thi Huong Nguyen ; Tho Anh Le ; Kiet Tuan Le
Journal of Malaria and parasite diseases Control 2004;0(3):61-68
Background: Can Gio mangrove forest is bio-diversified area. There is few studies on medical arthropod in Can Gio mangrove forest until now. Objective: To study bio-diversified feature and identify species with disease transmitting role. Subject and Method: In 2007, medical arthropod surveys were conducted at 3 sites located in the natural conserve zone- Can Gio mangrove forest. A cross-sectional study was used. Results and Conclusions: A total of samples of 6178 individuals of medical arthropod belonging to 65 species have been collected, including 3 species of flea (Siphonaptera), 1 species of ticks (Ixodidae), 6 species of chiggers (Trombiculidae), 6 species of mites (Gamasoidea), 25 species of flies (Muscoidea) and 24 species of mosquitoes (Culicidae). They belong to 37 genus, 17 families, 3 orders (Siphonaptera, Acarina and Diptera), and 2 classes (Insecta and Arachnida). 20 species having epidemiological role were found in Can Gio mangrove forest. The rate of Anopheles epiroticus biting human at night indoor, outdoor and daytime indoor is rather high, especially at the end of dry season at centre of the forest.
Mangrove forest
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medical arthropod
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species
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genus
3.Detection of virulence, specific genes and antibiotic resistance of isolated Salmonella spp. strains from rabbits infected with salmonellosis
Huynh Van CHUONG ; Nguyen Minh TUAN ; Nguyen Thi Nhu ANH ; Le Thi Lan PHUONG ; Nguyen Xuan HOA
Korean Journal of Veterinary Research 2023;63(2):e16-
Salmonella spp. are pathogens involved in most salmonellosis in rabbits. This study examined Salmonella disease in rabbits raised in Thua Thien Hue, Vietnam. Two hundred and 56 rectal swabs of rabbits were taken, and a carrier rate of 33.98% was found. In addition, all the isolated Salmonella spp. strains were 100% motile; positive for H2S, catalase, Voges Proskauer, coagulase, citrate, maltose, and dextrose; and negative for indole, methyl red, urease, oxidase, sucrose, and lactose. The Kirby-Bauer method showed that these Salmonella strains were susceptible to doxycycline (93.2%), tetracycline (84.1%), and levofloxacin (65.9%). On the other hand, they were highly resistant to streptomycin (95.5%), ampicillin (93.2%), colistin (40.9%), and gentamicin (34.1%). Furthermore, polymerase chain reaction used to screen for virulence and specific genes of Salmonella strains showed that all Salmonella strains isolated carried InvA, fimA, and Stn.
4.Applied research into the production process of gama - Globulin from Human Plasma and Standard gama - Globulin with Rich of Anti \u2013 HBs
Phan Trung Do ; Duong Tuan Pham ; Hien Thi Do ; Thuy Thi Tran ; Thin Duy Ngo ; Phuc Hanh Hoang ; Hai Xuan Le ; Tri Anh Nguyen
Journal of Medical Research 2008;0(1):67-71
Introduction: The need for gama \u2013 globulin, especially gama - globulin - anti \u2013 HBs, is huge in Vietnam. A number of patients cannot to afford use them due to the high price as they are imported. Meanwhile, Vietnam has high quality input sources for producing gama \u2013 globulin. \r\n', u'Objectives: To study the production process of gama - Globulin from Human Plasma and Standard gama - Globulin with Rich of Anti \u2013 HBs. \r\n', u'Subjects and method: 168 samples of human plasma from voluntary blood donors, which had been screened with for transfusion transmittable infections (TTLs), were chosen as plasma with rich of anti - HBs. The plasma with anti - HBsAg was precipitated with ethanol 25%, pH 6,9 to gain gama - globulin with rich anti - HBs, which was dried by Dutch Ly - 3 - TTE machine. Activation of anti - HBs gama - globulin was identified by a standard method of the degree of antibody specific for anti - HBsAg kit of BIORAD, \r\n', u'Results: The purity of the gama - globulin achieved was 93%, which was almost equal with the results of some foreign researchers (7.8), the activation of anti - HBs was 1:128 dilution degree. The productivity of gama - globulin gaining from 1 litter plasma was 6.0 gram. This new issue was first demonstrated in Vietnam. \r\n', u'Conclusion: We can domestically produce anti-Bs gama - globulin with high degree of activeness (1:128) from human plasma by the precipitating method with ethanol, pH and low temperature. \r\n', u'
Human plasma
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gama - globulin - anti - HBs
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Precipitation of ethanol
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pH and low temperature
5.Viral load suppression and acquired HIV drug resistance in adults receiving antiretroviral therapy in Viet Nam: results from a nationally representative survey
Vu Quoc Dat ; Bui Duc Duong ; Do Thi Nhan ; Nguyen Huu Hai ; Nguyen Thi Lan Anh ; Huynh Hoang Khanh Thu ; Tran Ton ; Luong Que Anh ; Nguyen Tuan Nghia ; Nguyen Vu Thuong ; Khuu Van Nghia ; Tran Thi Minh Tam ; Tran Phuc Hau ; Nguyen Duy Phuc ; Vu Xuan Thinh ; Nguyen Tran Hien ; Truong Thi Xuan Lien ; Silvia Bertagnolio ; Nguyen Thi Thuy Van ; Masaya Kato
Western Pacific Surveillance and Response 2018;9(3):16-24
Objective:
The purpose of this survey was to estimate the prevalence of viral load (VL) suppression and emergence of HIV drug resistance (HIVDR) among individuals receiving antiretroviral therapy (ART) for 36 months or longer in Viet Nam using a nationally representative sampling method.
Methods:
The survey was conducted between May and August 2014 using a two-stage cluster design. Sixteen ART clinics were selected using probability proportional to proxy size sampling, and patients receiving ART for at least 36 months were consecutively enrolled. Epidemiological information and blood specimens were collected for HIV-1 VL and HIVDR testing; HIVDR was defined by the Stanford University HIVDR algorithm.
Results:
Overall, 365 eligible individuals were recruited with a mean age of 38.2 years; 68.4% were men. The mean time on ART was 75.5 months (95% confidence interval [CI]: 69.0–81.9 months), and 93.7% of the patients were receiving non-nucleoside reverse transcriptase inhibitor-based regimens. Of the 365 individuals, 345 (94.7%, 95% CI: 64.1–99.4%) had VL below 1000 copies/mL and 19 (4.6%, 95% CI: 2.8-–7.5) had HIVDR mutations.
Discussion
Our nationally representative survey found a high level of VL suppression and a low prevalence of HIVDR among individuals who received ART for at least 36 months in Viet Nam. Continued surveillance for HIVDR is important for evaluating and improving HIV programs.
6.Update on antibiotic resistance of common pathogenical bacteria isolated in Hue University of Medicine and Pharmacy Hospital
Dinh Binh TRAN ; Viet Quynh Tram NGO ; Thi Bao Chi LE ; Thi Chau Anh NGUYEN ; Hoang Bach NGUYEN ; Van Bao Thang PHAN ; Thi Khanh Linh NGUYEN ; Nu Xuan Thanh LE ; Thi Dang Khoa NGUYEN ; Thi Tuyen NGUYEN ; Thi Thuy UNG ; Thi Hai DINH ; Thi Ngoc Mai DUONG ; Minh Ngoc HOANG ; Viet Tu NGUYEN ; Le Bich Ngoc HOANG ; Tuan Khoi TRAN ; Doan Hieu TRAN ; Thi Tuyet Ngoc TRAN ; Van An LE
Hue Journal of Medicine and Pharmacy 2023;13(7):66-74
Backgroud: The aim of this study is to update on antibiotic resistance of common pathogenical bacteria isolated in Hue University of Medicine and Pharmacy Hospital (Hue UMP Hospital). Methodology: Use of the agar disk diffusion method to test the susceptibility to antimicrobial agents of 3709 bacterial strains from infected patients hospitalized in Hue UMP Hospital in 2020 - 2022. Results: Among 3709 strains of pathogenical bacteria isolated, S.aureus was found with the rate of 29.9%, followed by E. coli (24.5%), Pseudomonas aeruginasa (17.8%), Enterococcus spp. (11.8%), Klebsiella spp (9.7%) and Acinetobacter spp (4.1%). The proportion of bacterial isolates has changed, but Staphylococcus aureus is still highest rate. S.aureus is resistant to many antibiotics, but MRSA strains have decreased significantly, from 73.3% in 2020 to 62.5% in 2022. Pseudomonas aeruginosa was resistant to some of the group A recommended antibiotics such as ceftazidime, piperacillin-tazobactam with the rate of 56.6% and 48.7%. The percentage of E. coli with ESBL strains (+) was at 28.2% - 30.3%. Enterococus spp strains are still sensitive to vancomycin (83.1% - 91.9%). The rate of Klebsiella ESBL (+) is only 6.9% to 8.2%. The strains of Acinetobacter spp were highly resistant to Piperacillin (100%) and Ceftriaxone (96.5%) but they are still sensitive to imipenems 70 - 71%, highly sensitive to Doxycillin (95.2%) and Cefotaxime (88.4%). Conclusion: Many bacterial strains are resistant to many commonly antibiotics. Providing timely, regular, and effective management of antibiotic resistance patterns for common pathogenic bacteria in hospitals, will help reduce the risk of bacterial resistance.