1.The status of melasma in non- pregnant women
Journal of Practical Medicine 2005;512(5):71-73
Study on 274 non-pregnant women with melasma at the age of 15-67, treated in Hanoi Dermatology Hospital from November 2001 to October 2004. The results: melasma was a common disease in all of age of woman, but it accounted for 86.49% in 25-55 years old group. Melasma with localized lesions in epithelium accounted for high percentage (58.03%) then mixed lesions (20.2%). The lesions occurred in both 2 cheeks among 50.73% of worker and farmer patients. 6.56% of patients with pigment disorder skin disease, 26.64% patients with chronic disease, 19.7% of patients had related factors such as spontaneous abortion, abortion or taking contraceptive pills, 9.72% of patients had endocrine diseases
Melanosis
;
Women
;
Pregnant Women
2.The effects of melasma treatment by hydroquinon combined with sun cream
Journal of Practical Medicine 2004;471(1):19-21
30 patients with check sunburn, aged 18-60 years old treated by hydroquinone 2% in combining with sun protected cream. After 6 moths pigment reduced by 45,6%, mean size of lesion reduced by 78%. 90- 100% of patients had the size of lesion reduced by 13,4% and 61% of patients had the size of lesion reduced by 70-89%.
Therapeutics
;
Melanosis/therapeutic use
;
Hydroquinones
3.Evaluating the effects of chloasma treated by Hydroquinon combined retinoic acid.
Journal of Practical Medicine 2004;474(3):39-40
30 patients with melasma (diagnosed according to Zaumseil, Klaus-Graupe) was treated by applying 2% hydroquinone in combing with 0.05% retinoic. After 6 month treatment, the disease recessed well and very well in 65.6%, the size of pigmented area reduced 87% in average, 15.6% of patients has reduced in 90-100% of size and 65.7% of 70-89%.
Melanosis
;
Therapeutics
;
Hydroquinones
;
Tretinoin
4.The evaluation on treatment results of melasma with hydroquinon
Journal of Practical Medicine 2004;478(4):57-58
30 patients aged 18-60 years old with melasma localized at the epiderm and epiderm plus mesoderm layer topically treated by 2% hydroquinone preparation within 6 months at the Venero-dermatol Institute were evaluated. Good and very good results reached in 42.5%. The size of lesion minimized by > 10% each months, especially 21% in the 2nd month. Mean size of lesion minimized by 75%. In 11.2% of patients, the size of lesion minimized by 90-100% and 56.3% of patients had got the lesion of 70-89% minimized size.
Therapeutics
;
Melanosis
;
Hydroquinones
5.To assess the results of melasma treatment by bleaching hydroquinon in combination with retinoid acid and sun cream
Journal of Practical Medicine 2005;0(12):9-10
Treatment for 30 patients with melasma according to standard of Zaumseil, Klaus-Graupe by bleaching hydroquinon in combination with retinoid acid and sun cream. After 6 months, the result showed that: reduced 70% pigment of injury. Size of average injury reduce 87,1% after treatment. In 16,7% patients, the size reduce 90-100% and in 70%, the size reduce 70-89% after treatment.
Melanosis
;
Therapeutics
;
Hydroquinones
;
Pharmaceutical Preparations
6.Implementation of regulations of occupational disease prevention and control and working safety from 1964
Journal of Practical Medicine 2002;435(11):9-11
An interview of 1950 persons who worked at 37 companies in 7 localities that has high risks of working accidents and occupational disease. Results have shown that the document system was relatively complete to contribute importantly to the health care, detection of occupational disease- and implementation of regime related with working people. The implementation of regulations of working protection for working people suffered the occupational disease was quite well: 86,3% of companies considered in the health care and periodical consultation. The ways of reduction of dust have not properly been considered. Most of working people knew the risk of pulmonary dust, bronchitis and occupational deaf
Occupational Diseases
;
Safety
7.The situation of management and utilization of plant protective chemicals and laborer health
Journal of Practical Medicine 2002;435(11):31-33
1667 laborers were interviewed on using the plant protective chemicals in 16 communes of 8 provinces: §ång Nai, L©m §ång, TiÒn Giang, B×nh D¬ng, B×nh Phíc, Ninh ThuËn, B×nh ThuËn, Kh¸nh Hßa in year 2000. Results: 100% or farm households were using plant protective chemicals. Number and types of plant protective chemicals used are various. The management of plant protective chemicals remained to be not tightly. They are used unsafe and inappropriately, cause effects on the laborer health and toxicity. The incidence of Tb toxicosis is 22.92 per 10,000 people. The incidence of Padan toxicosis is highest.
Chemistry
;
Agrochemicals
;
therapeutics
8.Preventive medicine in Vietnam, achievements during 1991-2000 and strategy during 2001-2010
Journal of Medical and Pharmaceutical Information 1999;(9):3-6
This paper introduced the achievements of preventive medicine during past the years (1991-2000), including the epidemic disease prevention and control, malaria control, HIV/AIDS prevention and control, public nutrition, health quarantine in the border, school based health, strengthen organization and health staff of preventive medicine network research and application of scientific and technological achievements.
Preventive Medicine
;
Achievement
9.To promote military and civilian joining forces for establishing the national defense and public health care system.
Journal of Medical and Pharmaceutical Information 2000;(2):4-5
Military and civilian health joining is a valuable tradition of civilian and military health, developed since the August Revolution and now is developing increasingly. This is the cause of whole health sector. In 1998, the Ministry of Health combined with the Ministry of Defense to implement the program 12: Military and Civilian Health Joining for establishing the national defense and public health care with aims are: control diseases and epidemics, improve the quality of both civilian and military health services, develop efficiently the national health programs, training and scientific researches.
Delivery of Health Care
;
Military Personnel
;
public health
10.Increased Neutrophil Elastase in Affected Lobes of Bronchiectasis and Correlation of Its Levels between Sputum and Bronchial Lavage Fluid
Lam NGUYEN-HO ; Hoang Kim Tu TRINH ; Vu LE-THUONG ; Kieu Minh LE ; Van Thanh Niem VO ; Diem My VU ; Ngoc TRAN-VAN ; James D. CHALMERS
Tuberculosis and Respiratory Diseases 2025;88(2):399-407
Background:
Neutrophil elastase (NE) has been proposed as a potential biomarker for evaluating the severity and prognosis of bronchiectasis. This study aimed to compare bronchial lavage quantification of NE levels and activities with those of sputum.
Methods:
A cross-sectional study was conducted in which 24 Vietnamese adults with bronchiectasis were enrolled from June 2023 to August 2023. All participants underwent bronchoscopy to collect bronchial lavage fluid (BLF) from two bronchial locations: one in the region with the greatest bronchial dilatation and one in the normal bronchi or in patients with all lobes affected, the least abnormal lobe (abnormal BLF [ABLF] and normal BLF [NBLF], respectively). Spontaneously expectorated sputum was also collected.
Results:
Out of 24 cases, the prevalence of mild, moderate and severe bronchiectasis was 14/24 (58.4%), 5/24 (20.8%), and 5/24 (20.8%), respectively. NE concentration and activity were significantly higher in sputum and ABLF than in NBLF (p<0.001). Sputum and ABLF were highly correlated (r=0.841, p<0.001) with no significant difference in NE activity between sputum and ABLF. Higher levels of NE activity were seen in more severe bronchiectasis than in mild bronchiectasis in all samples but were only statistically significant for NE activity in sputum (r=0.418, p=0.042).
Conclusion
NE activity and concentration are elevated in areas of the lung most affected by bronchiectasis. Sputum is a valid surrogate of pulmonary NE levels, as they correlate strongly with ABLF and confirm in a Vietnamese population the relationship between NE activity and disease severity.