In 2001-2002 period, at the Hospital of Hemotology and Blood Transfusion of Ho Chi Minh, a cross-sectioncal analytic descriptive study was carried out covering 92 cases thrombocyte transfusion for 67 patients with acute myoblastic and lymphoblastic leucemia. The results were analogue with those obstained by foreign authors concerning the indices of assessment of the efficacy of thrombocyte transfusion. The number of thrombocytes in a condensed unit of blood plaquettes obtained on the apparatus of extraction and isolation in comparing with body weight of Viet Nam subject had created optimal doses of thrombocyte transfusion in patients without associated factors increasing the consumption of blood plaquettes and these are the doses possibly attained in Vietnamese blood donor
Leukemia, Lymphocytic, Acute ; Platelet Transfusion ; Blood

OBJECTIVES: The average alcohol consumption per capita among Vietnamese adults has consistently increased. Although alcohol-related disorders have been extensively studied, there is a paucity of research shedding light on this issue among Internet users. The study aimed to examine the severity of alcohol-related disorders and other associated factors that might predispose individuals towards alcohol usage in a sample of youths recruited online. METHODS: An online cross-sectional study was conducted with 1,080 Vietnamese youths. A standardized questionnaire was used. Respondent-driven sampling was applied to recruit participants. Multivariate logistic and Tobit regressions were utilized to identify the associated factors. RESULTS: About 59.5% of the males and 12.7% of the total youths declared that they were actively using alcohol. From the total sample, a cumulative total of 32.3% of the participants were drinking alcohol, with 21.8% and 25.0% of the participants being classified as drinking hazardously and binge drinkers, respectively. The majority of the participants (60.7%) were in the pre-contemplative stage. CONCLUSIONS: A high prevalence of hazardous drinking was recognized among online Vietnamese youths. In addition, we found relationships between alcohol use disorder and other addictive disorders, such as tobacco smoking and water-pipe usage. Our results highlighted that the majority of the individuals are not receptive to the idea of changing their alcohol habits, and this would imply that there ought to be more government effort towards the implementation of effective alcohol control policies.
Adolescent ; Adult ; Alcohol Drinking ; Alcohol-Related Disorders ; Asian Continental Ancestry Group* ; Cross-Sectional Studies ; Drinking ; Humans ; Internet ; Male ; Prevalence ; Risk Factors* ; Smoking ; Surveys and Questionnaires* ; Vietnam

Background: The genus Alpinia is one of the diverse genera in Thua Thien Hue province, in which many species have been used as medicine. But until now, studies on A. vietnamica have rarely been reported. Objectives: The present study was aimed at the determination of microscopic characteristics and chemical compositions as well as evaluating the antioxidant and acetylcholinesterase inhibitory activities of A. vietnamica. Materials and methods: A. vietnamica was collected in Phong Dien district, Thua Thien Hue province. Anatomic structures and powder properties were determined by the microscopic method. Phytochemical screening was conducted by specific chemical reactions. The Folin-Ciocalteau method and the aluminum chloride-flavonoid assay, respectively, were used to quantify the total polyphenol (TPC) and total flavonoid contents (TFC). Antioxidant activity was assessed using the DPPH assay, while acetylcholinesterase (AChE) inhibitory activity was evaluated using the Ellman method. Results: The microscopic characteristics of this species have been described. Phytochemical analysis results revealed the presence of flavonoids, coumarins, and tannins in A. vietnamica. The ethanol extract from the aerial part of A. vietnamica had higher polyphenol and flavonoid contents than the underground part extract. Moreover, this extract also displayed a stronger DPPH radical scavenging and exhibited AChE inhibitory activities. Conclusion: This is the first report on the microscopic characteristics, chemical compositions, and biological activities of A. vietnamica.

Backgroud: The aim of this study is to update on antibiotic resistance of common pathogenical bacteria isolated in Hue University of Medicine and Pharmacy Hospital (Hue UMP Hospital). Methodology: Use of the agar disk diffusion method to test the susceptibility to antimicrobial agents of 3709 bacterial strains from infected patients hospitalized in Hue UMP Hospital in 2020 - 2022. Results: Among 3709 strains of pathogenical bacteria isolated, S.aureus was found with the rate of 29.9%, followed by E. coli (24.5%), Pseudomonas aeruginasa (17.8%), Enterococcus spp. (11.8%), Klebsiella spp (9.7%) and Acinetobacter spp (4.1%). The proportion of bacterial isolates has changed, but Staphylococcus aureus is still highest rate. S.aureus is resistant to many antibiotics, but MRSA strains have decreased significantly, from 73.3% in 2020 to 62.5% in 2022. Pseudomonas aeruginosa was resistant to some of the group A recommended antibiotics such as ceftazidime, piperacillin-tazobactam with the rate of 56.6% and 48.7%. The percentage of E. coli with ESBL strains (+) was at 28.2% - 30.3%. Enterococus spp strains are still sensitive to vancomycin (83.1% - 91.9%). The rate of Klebsiella ESBL (+) is only 6.9% to 8.2%. The strains of Acinetobacter spp were highly resistant to Piperacillin (100%) and Ceftriaxone (96.5%) but they are still sensitive to imipenems 70 - 71%, highly sensitive to Doxycillin (95.2%) and Cefotaxime (88.4%). Conclusion: Many bacterial strains are resistant to many commonly antibiotics. Providing timely, regular, and effective management of antibiotic resistance patterns for common pathogenic bacteria in hospitals, will help reduce the risk of bacterial resistance.

Backgrounds: Fecal occult blood testing (FOBT) is commonly used in colorectal cancer screening programs. Many studies have compared different FOBT methods, but the correlation between traditional red cell microscopy and FOBT remains unclear. Objectives: 1) To evaluate the rate of positive FOBT in patients with different disease groups; 2) To compare the sensitivity and specificity of red blood cells detection in fresh stool by microscopy technique and FOBT. Materials and methods: This was a cross-sectional study involving 120 patients from Hue University of Medicine and Pharmacy Hospital who requested a stool test from 4/2021 to 4/2022. Fresh stool samples were examined for the presence of red blood cells using traditional microscopy and FOBT technique. Results: The overall positivity rate of FOBT was 20%, and in the group of gastrointestinal diseases (n = 24), clinical anemia (n = 21), hepatobiliary diseases (n = 26) and other diseases (n = 49), it was 37.5%, 23.8%, 11.5% and 14.3%, respectively. In comparison with the FOBT technique, microscopic RBC detection had a sensitivity of 33.3% and a specificity of 100%. Conclusions: A high rate of fecal occult blood tests was observed in patients with gastrointestinal disorders. Microscopic erythrocyte detection has low sensitivity and many disadvantages compared to the rapid test. This rapid test should be widely used in clinical practice to aid in the diagnosis of gastrointestinal bleeding