In the year period of 1998-2002, in the Hospital N07 in Hai Duong province and the Hospital Buu Dien in HaNoi. 117 patients (99 females and 18 males, aged 17-69) who were clinically diagnosed as thyroid nucleous, goiter were undergone a fine needle puncture biopsy. Results showed a consistency between clinical diagnosis and ultrasound in 92.9% of solid form, 93.1% liquid form and in mixt form, the consistency rate was lower 55.5%. Between clinical diagnosis and ultrasound, there was a consistency in the determination of 76% of the number of goiters, and the consistency rate was higher between these 2 diagnostic methods, 81/85 in solid form and 25/27 in liquid form, while in mixt form the technique of fine needle aspiration puncture notified more cases than ultrasound 11 versus 5
Thyroid Gland ; ultrasonography ; Goiter

From 1998 to 2002, 117 patients (99 females, 18 males, aged 17-69) with thyroid nucleus tumors at Hospital 7 in Hai Duong and Hospital Buu Dien I in Hanoi was given percutaneous injected ethanol. Among 82/117 patients (70.1%) good results and 29/117 (24.8%) moderate results achieved. With mononucleus tumor 67 patients had got good results, 15 with moderate results and 2 without results. With polynucleus tumor, 15 patients had got good results, 14 moderate results and 4 without result. The treatment was safe complications were not severe and easy to manage
Ethanol ; Thyroid Gland ; Neoplasms

Background:Asthma is a chronic disease. Its characteristic is a chronic process of infection on respiratory leading to obstructed respiratory airway. In order to evaluate the obstructed respiratory disorder on asthma children, there are many various methods in which two methods are been applied widely: measure respiratory function and measure the resistance of respiratory airway. Objectives:This study aims to learn aboutthe respiratory airway resistance of asthmatic children from 6 to 10 years old at Respiratory Department of Saint-Paul hospital. Subjects and method: A retrospective, cross sectional and descriptive study was conducted on 135 children with asthma hospitalized at the Pulmonary Division at the Hospital Saint - Paul from January to October 2006. Results:- Value through thoracic pulmonary resistance in children asthmatics:The average resistance of the respiratory tract had inspiration: 7.31 \xb1 2.14 hPa.s L -1 . The average resistance of the respiratory tract had expiration: 8.30 \xb1 2.42 hPa.s L -1. There was no significant difference in the resistance of the respiratory tract between boy and girl children. Conclusion: Thoracic pulmonary resistance decreased with age from 6 to 10 years. After the inspiration of Ventolin, resistance of the respiratory tract decreased of 22.2% in the inspiration and 17.5 in expiration. The difference was significant.
Asthma/ pathology ; therapy ; Child

Background: Idiopathic or Immune Thrombocytopenic Pupura (ITP) is a common disease in Vietnamese children. This is a hemostatic disorder disease diagnosed by clinical symptoms combining with tests of platelet quantity in peripheral blood and other tests. Objectives: to study epidemiology, clinical, para-clinical characteristics and their relations in ITP disease. Subjects and methods: This was a prospective and retrospective study. The study included 579 pediatric patients from 3 months to 16 ages who were diagnosed and treated ITP disease in National Pediatric Hospital from 1/1/2003 to 12/31/2004. Results: Data were analyzed, including 191 infants from >3-<12 months (33.0%), 293 children from 1 - 10 ages (50.6%), 95 children >10-<16 ages (16.4%). The male/female ratio was highest in infants and decreased with age (P < 0.001). The disease occurred more in September, October and November with advantage factor being acute respiratory infection before 2 to 3 weeks. Subcutaneous hemorrhage ratio was highest with 557 cases (96.2%), intracranial hemorrhage happened in 7 cases (1.7%). There were differences among age groups about hemorrhage situation. Anemia level did not corresponding with the decrease of the platelet count. Conclusion: Characteristics of ITP depend on the number of platelet and age. \r\n', u'\r\n', u'\r\n', u'
Purpura ; Thrombocytopenic ; Idiopathic/ epidemiology

Background: The intracranial hemorrhage (lCH) in infant due to vitamin K deficiency were been informed a lot at all over the world since the year of 80's. In Viet Nam, in recent years, this disease still most occurs which account for 110-130 children/100000 alive infant. The intracranial hemorrhage (lCH) in infant causes severe neurological, psychiatric sequelae. Objectives: This study aims to analyze the characteristics of epilepsy, changing of electroencephalogram and lesions of brain after intracranial hemorrhage in infant. Subjects and method:A descriptive, cross sectional study was conducted on 97 infant patients with the age ranged from 8 days to 3 months years old whom treated in National Hospital for Peadiatric. Results: Epilepsy was common (45.3%), with generalized seizures in 24.7% , partial seizures in 20.6%. The main intracranial lesions were cerebral cyst and atrophy in right or left hemisphere or both sides. Electroencephalic activity was found impaired in most of patients: Disorder of background waves in 19.6 %, low localized waves in 31%, proxystic ativity with spike in 45.3% and decrease in electroencephalographic amplitude in cystic areas. Conclusion: The epilepsy, abnormal electroencephalographic activities, severe lesions of brain were common after intracranial hemorrhage in infant.
Intracranial Hemorrhages/ diagnosis ; pathology ; therapy ; Infant

Background: Shigella-induced diarrhea has been considered a major health problem leading to high morbidity and mortality. This disease can lead to dire consequences; however, the true burden of the disease, including the costs and sequalae associated with shigellosis is not yet known. Objectives: (1) To describe the health seeking behavior and the way of payment of population when suffering Shigella; (2) To identify and analyze the direct household costs associated with the treatment of diarrhea due to Shigella. Subjects and method: 290 patients of all ages with positive Shigella diarrhea admitted to public health facilities in Nha Trang, Khanh Hoa province in the period from August 2002 to January 2004 were included in the study. The subjects were divided into three age groups, the first 0-5, second 5-18 and the last one was over 18 years old. Patients and their relatives were interviewed at three stages - day 7, day 14 and day 90 - to obtain all the required information. Results: 134 of 290 patients (47%) paid for using the other health care services before admission to the study\u2019s facilities. The average direct cost per episode for the patients at group aged 0-5 was 129,000 VND, group aged 6-18 was 59,267 VND and over 18 years old was 173,531 VND; it was 131.960 VND for three groups. Comparison with the average household expenditure for health care, it was higher in the poorer group and it was lower three times than the richest group. The average direct medical cost per episode was higher the average direct non-medical cost per episode for all groups. Conclusions: The average direct cost per episode of Shigellosis treatment was rather high especially the average direct cost for the treatment at the health facility. It was also high compared with the average expenditure for health per capita so that it becomes large economic burden for households.
Direct cost ; Shigella ; treatment

OBJECTIVES: The prevalence of diabetes mellitus is rapidly increasing in Vietnam, particularly among adults aged over 45 years. This study estimated trends in diabetes and prediabetes prevalence and determined risk factors in Vietnamese adults (over 45 years). METHODS: A cross-sectional study was conducted based on data from an annual diabetes screening program among people aged 45-69 years in an urban city in central Vietnam (Da Nang). Joinpoint regression analyses were performed to calculate the annual percentage change and ptrend-values. Multinomial logistic regression analysis was used to determine risk factors. RESULTS: In total, 3,765 men and 9,149 women were included in this analysis. The age-adjusted prevalence of diabetes and prediabetes in 2017 was 11.4% and 52.9%, respectively. The prevalence of diabetes was higher in men (15.1%) than in women (10.3%), but that of prediabetes was similar in both genders (53.4% vs. 52.8%). The prevalence of prediabetes significantly increased during the study period, whereas no upward or downward trend for diabetes was observed. The prevalence of obesity, abdominal obesity, hypertension, and dyslipidemia showed no obvious trend. Obesity, a high waist-to-hip ratio, hypertension, more severe abdominal obesity, and dyslipidemia were significantly associated with a higher risk of diabetes and prediabetes. CONCLUSIONS Diabetes and prediabetes were more prevalent among people aged over 45 years than in the general population. Da Nang has experienced a marked increase in the prevalence of prediabetes. These findings have significant implications regarding the need for nationwide public health interventions and management aiming at diabetes prevention and control.

A new compound, 3β-acetoxylanosta-7,9(11),24-triene-26-al (3), and seven known compounds (1 – 2 and 4 – 8) were isolated from Ganoderma tropicum (Jung.) Bres. collected in Tay Nguyen, Vietnam. The structures of these compounds were determined by one- and two-dimensional nuclear magnetic resonance spectroscopy, electrospray ionization mass spectrometry (ESI-MS), and high-resolution ESI-MS, and by comparison with literature data. All of the isolated compounds were tested for nitroblue tetrazolium (NBT) reduction activity in Saccharomyces cerevisiae-stimulated RAW 246.7 cells. Among them, compounds 2 – 4 and 6 – 8 enhanced the NBT reduction in a dose-dependent manner.

OBJECTIVES: The prevalence of diabetes mellitus is rapidly increasing in Vietnam, particularly among adults aged over 45 years. This study estimated trends in diabetes and prediabetes prevalence and determined risk factors in Vietnamese adults (over 45 years). METHODS: A cross-sectional study was conducted based on data from an annual diabetes screening program among people aged 45-69 years in an urban city in central Vietnam (Da Nang). Joinpoint regression analyses were performed to calculate the annual percentage change and ptrend-values. Multinomial logistic regression analysis was used to determine risk factors. RESULTS: In total, 3,765 men and 9,149 women were included in this analysis. The age-adjusted prevalence of diabetes and prediabetes in 2017 was 11.4% and 52.9%, respectively. The prevalence of diabetes was higher in men (15.1%) than in women (10.3%), but that of prediabetes was similar in both genders (53.4% vs. 52.8%). The prevalence of prediabetes significantly increased during the study period, whereas no upward or downward trend for diabetes was observed. The prevalence of obesity, abdominal obesity, hypertension, and dyslipidemia showed no obvious trend. Obesity, a high waist-to-hip ratio, hypertension, more severe abdominal obesity, and dyslipidemia were significantly associated with a higher risk of diabetes and prediabetes. CONCLUSIONS Diabetes and prediabetes were more prevalent among people aged over 45 years than in the general population. Da Nang has experienced a marked increase in the prevalence of prediabetes. These findings have significant implications regarding the need for nationwide public health interventions and management aiming at diabetes prevention and control.

A new compound, 3β-acetoxylanosta-7,9(11),24-triene-26-al (3), and seven known compounds (1 – 2 and 4 – 8) were isolated from Ganoderma tropicum (Jung.) Bres. collected in Tay Nguyen, Vietnam. The structures of these compounds were determined by one- and two-dimensional nuclear magnetic resonance spectroscopy, electrospray ionization mass spectrometry (ESI-MS), and high-resolution ESI-MS, and by comparison with literature data. All of the isolated compounds were tested for nitroblue tetrazolium (NBT) reduction activity in Saccharomyces cerevisiae-stimulated RAW 246.7 cells. Among them, compounds 2 – 4 and 6 – 8 enhanced the NBT reduction in a dose-dependent manner.