1.Rickets in children from 1 - 6 month old at Hai Phong Children Hospital in two years (2002 - 2003)
Journal of Vietnamese Medicine 2004;304(11):40-47
The study of 122 children were rickets from 1 - 6 month old at Hai Phong Children Hospital from 2002 to 2003. The results: the most of mothers were in shortage of knowledge in rickets. There were many risk factors: mothers keeping their child from sunlight after birth, mothers on diet for the first 3 months, solid food complement before 4 months. Frequent signs of rickets were crying all the time, perspiration, alopecia. Hypocalcemia was found in 80.33%
Rickets
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Child
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Epidemiology
2.Study on pharmacological effects of Vietnamese ginseng leaves
Journal of Medicinal Materials - Hanoi 2005;10(1):27-32
Vietnamese ginseng leaves had the effect on the central nervous system, shortening pentobarbital-induced sleeping time in smaller doses and lengthening pentobarbital- induced sleeping time in larger doses. Vietnamese ginseng leaves extract (600, 1200mg/kg p.o) and its total saponin (200mg/kg p.o) significantly recovered the stress-induced decrease in pentobarbital sleep to the normal level. In the other hand, Vietnamese ginseng leaves extract and its total saponin have the invigoration and antioxidant effects
Plants, medicinal
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Pharmaceutical Preparations
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Panax
3.Studies on Antistress and Antioxidant Effects of Schefflera elliptica (Blume) Harms. Araliaceae
Journal of Medicinal Materials - Hanoi 2003;8(4):114-118
Both ethanol extracts of the bark and leaves of Schefflera elliptica (Blume) Harms (Araliaceae) showed antistress effect on mice at the oral doses of 158 and 167 mg/kg body weight, respectively. The bark proved to be more effective than the leaves, and their efficacity increased with the doses. Both extracts possessed in vitro antioxidant activity at the concentrations of 50-100 mcg/ml, the bark also being more effective than the leaves. The total saponin extract of the bark exhibited antioxidant effects at the levels of 5-25 mcg/ml. So, saponins might be the chemical constituents determining the antioxidant activity.
Plants
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Biochemistry
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Araliaceae
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Therapeutics
4.The characteristics of female employees’ health in agricultural production
Journal of Practical Medicine 2005;530(11):56-58
Study on 5409 female employees who were directly taking part in agricultural production in 3 regions: the North 1794 persons; the Central 1805 persons; the South 1810 persons. 1218 persons were randomized for clinical examination: the North 418 persons, the Central 392 persons and the South 408 persons. 293/1218 persons were selected for examination of worm eggs. Results: the rate of gynecological disease was 19-23%; dermatological disease in the North was rate of 20.11%, the Central 23.97%, the South 37.64%; Muscular disease was 15.5-18.5%. The infection rate of ascaris was 78.5%, the negative rate was only 8.5%. The physical indexes of female employees were in normal limitation of Vietnamese people.
Health
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Agricultural Workers' Diseases
5.Technique of reconstruction of the dental stem defect by the false cast and post
Journal of Vietnamese Medicine 1999;232(1):59-65
50 patients with 50 teeth with dental stem defect due to the endodontis (74%) and other causes received the reconstruction by false cast and post. The primary results found that the rate of good reconstruction was 88%. The shortcomings of technique comprised longer duration of reconstruction and higher cost
Dental Care
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Delivery of Health Care
6.Production of serum against neurotoxin alpha from NAJA KAOUTHIA.
Journal of Preventive Medicine 2002;12(1):17-23
Lethal component of the Naja kaouthia venom had been purified and used as antigen for producing antiserum according to an immunization protocol aiming to be efficient in the production of high affinity antibodies. A strong response was observed on all six immunized horses and tolerance to the antigen did not occur. All antitoxin sera obtained protected against lethality due to the entire venom. The potential production of these six horses is estimated to 4,300 doses/year compared to the estimated national need of 4,800 doses/year for a population of 80 millions.
Neurotoxins
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serum
7.Surveillance of the relationship between arteriosclerosis condition and the changes of some coagulation factors
Journal of Vietnamese Medicine 2003;280(1):46-55
Studying retrospectively 117 cases of atherosclerosis in the Hospital of Hematology and Blood Transfusion in Ho Chi Minh city showed that: atherosclerosis is very common in elderly and the form of calcified plaque accounts for highest rate. Atherosclerosis is usually associated with other pathological status such as CHA, blood lipid disorder, diabetes and obesity
Blood Coagulation Factors
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Arteriosclerosis
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Blood
8.Studies on Antioxidant Activity of Polyscias fruticosa Harms. (Araliaceae)
Journal of Medicinal Materials - Hanoi 2003;8(5):142-146
Extracts from roots and leaves of Polyscias fruticosa Harms. (Araliaceae) and their combination have been studied on lipid peroxidation in mouse brain using an auto-oxidation and a free radical generating system: the Fenton’s reagent (ferrous iron + hydrogen peroxide). All the root, leaf and combined extracts have inhibitory action on peroxidation of lipids and trolox, a water-soluble analogue of vitamin E used as a reference antioxidant compound. The results also indicate that the leaf extract is the strongest of all.
Biochemistry
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Plants
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Plants, Medicinal
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Araliaceae
9.Study on the tocolysis effectiveness of nifedipin on uterine contraction in the management of preterm labor
Journal of Medical Research 2005;36(3):44-52
A clinical trial was performed to evaluate the tocolytic possibility of nifedipin and to propose a treatment regimen for preterm labor in the National Hospital of Gynecol-Obstet from July 2003 to December 2003. There were 40 cases of preterm labor with gestational age 31 weeks and 3 uterine contractions per minute on average. Patients received a 10 mg sublingual loading dose every 20 minutes (maximum dose 40mg), and followed by 20 mg oral dose every 6- 8 hours. Result: the effectiveness in tocolysis of nifedipin is very fast. It took 60-80 minutes to arrest uterine contraction (70- 80%) (including contractions of high frequency and intensity), especially in urgent tocolysis. The lower the frequency and intensity is, the higher and sooner the effectiveness is. 92.5% of delivery were delayed for 48 hours. 82.85% were postponed until 36 weeks, and the mean time of prolonged pregnacy was 39 days. Side-effects were mild and transient and in normotensive pregnant women blood pressure was almost unaffected. This treatment regimen of nifedipin showed the effectiveness in preterm labor. In brief, nifedipin is an effective, safe, convenient and economic tocolytic agent. It may well represent the best suitable tocolytic alternative currently available and can be used widely in Viet Nam.
Obstetric Labor, Premature, Nifedipine, Tocolysis
10.Studies on hepatoprotective activity of Polyscias fruticosa based on antioxidant mechanism
Journal of Medicinal Materials - Hanoi 2004;9(3):85-89
Experimentally, hepatoprotective effect of DinhLang was expressed in mice. The extract of Dinh Lang leaf suppressed the increase of MDA level in brain and in liver of mice suffered from CCl4- induced hepatitis with antioxydant activity stronger than that of mixed extract and extract prepared from the root. Dinh Lang had manifested liver protective effect in tetrachlorurcarbone –induced acute hepatitis. Antioxydant effect expressed in the inhibition against the processes of peroxydation of cell membrane can be one of the mechanism of liver protective effect of Dinh Lang
Antioxidants
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Araliaceae
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liver