1.Isolation of Flavonoids from Excoecaria cochinchinensis Lour. var. cochinchinensis
Journal of Medicinal Materials - Hanoi 2003;8(4):103-107
The remedy Excoecaria cochinchinensis Lour. var. cochinchinensis (Euphorbiaceae) has been commonly used in folk medicine for the treatment of itches, furuncles, allergies. Previous reports have examined the chemical composition of the leaves, two compounds have been isolated and identified as gallic acid (FAD1) and ellagic acid (FAD 2). This study was carried out for the isolation and identification of the other chemical constituents. The leaves of E. cochinchinensis Lour. var. cochinchinensis were collected at Ha Noi city and Thai Binh province. The ethyl acetate extract of the leaves were successively chromatographed on silica gel G 60 and Sephadex LH-20 columns to afford two compounds named FAD 7 and FAD 8. The spectral analysis performed on EIMS, 1H-NMR and 13C-NMR has identified FAD7 as kaempferol 7-0-glycoside, and FAD 8 as kaempferol. These two flavonols were isolated from the leaves of the plant for the first time.
Plants
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Medicine, Traditional
;
Biochemistry
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Flavonoids
2.Influence of the iodized salt program in community on the determination of thyroid gland function by using radioimmunoassay and immunometric assay
Journal of Preventive Medicine 2002;12(1):36-40
The study was conducted on 82 simple goiter patients and 91 Basedow patients after at least one year using iodized salt daily. The results showed that the uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and Basedow patients decreased after 2 and 24 hours taking an oral dose of radioactive iodine. Especially, the decrease was 40-50% in simple goiter patients. The concentration of T3, T4, TSH in the sera was as following: in the simple goiter patients, the concentrations of T3 and TSH were slightly decreased, and the T4 serum concentration was increased. However, all the values were still within the normal range of euthyroidism. In Basedow patients, the concentrations of T3, T4, and TSH have not changed.
Iodine
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Radioimmunoassay
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Thyroid Gland
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Sodium Chloride, Dietary
3.Influence of use of iodine containing salt in the publicity on the thyroid function by some tests of nuclear medicine
Journal of Vietnamese Medicine 1998;6(2):1-5
The study was conducted in 82 simple goiter patients and 91 patients with Basedow’s disease after at least one year using iodized salt daily. The result showed:- The uptake of radioactive iodine (RAIU) by the thyroid gland of simple goiter and patients with Basedow’s disease decreased after 2 and 24 hours taking an oral dose of radioactive iodine, specially in simple goiter patients decreased 40-50%. -The serum concentrations of T3, T4, TSH were following: in simple goiter patients, the serum concentrations of T3 and TSH were little decreased and the T4 serum concentration was increased. However, all the values were still in the normal range of euthyroidism. In patients with Basedow’s diseased the serum concentrations of T3,T4,TSH have not been changed
Nuclear Medicine
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Thyroid Function Tests
4.Effect of green bean (vigra radiata wilczek) on lipid peroxidation in vitro and in vivo
Ha Thi Nguyen ; Huyen Thi Thu Nguyen
Journal of Medical Research 2007;49(3):83-90
Background: Lipid peroxidation is considered that is one of the causes of pathological processes. Green bean is not only a food of high economic value but also a good medicine. Objective: To investigate the effects of green bean on (1) the lipid peroxidation in mitochondria of rat liver cell, (2) the index in blood of rabbits exposed to radiation: the activities of antioxidant enzymes (SOD, GPx), concentrations of MDA and TAS. Subjects and methods: In vitro experimental model was used to estimate the effects of green bean on lipid peroxidation in mitochondria of rat liver and in vivo experimental model was used to investigate the effects of green bean on the activities of free radicals in blood of rabbits exposed to radiation. Results and Conclusions: (1) Total green bean decreased the lipid peroxidation in mitochondria of rat liver cell without dependence onagents induced lipid peroxidation such as Fe3+.ADP/NADPH or Cumene hydroperoxid, (2) Green bean concurrently inhibited the decreased activities of SOD, GPx, TAS and the increased concentration of MDA in blood of rabbits radiated with 5 Gy dose. \r\n', u'\r\n', u'\r\n', u'
Antioxidants
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Lipid Peroxidation
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5.Some comments about sex and average age of cerebral palsy
Journal of Practical Medicine 2003;466(11):54-57
In studying 155.633 subjects living in Ha Tay, among them 238 suffered from cerebral palsy, 54% of cases are male, 46% female. Gender ratio male/female: 1.16, varying with age groups. The highest 1.9 in under 10 years of age group. The lowest 0.2 of > 50 years of age group. Cerebral palsy patients mean age are 18.2 versus 28.3 of normal population in this survey. Average age and maximal age of cerebral palsy patients in Ha Tay are lower than those of the patients in developed countries
Cerebral Palsy
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Brain
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Brain Diseases
6.To evaluate the density on the upper part of femurs on elders by unigamma-plus
Journal of Practical Medicine 2005;505(3):35-37
A study on 90 people ( 62 male and 30 female) who had history of bone fracture due to serious trauma was conducted in Friendship Hospital. The result showed that: the age and BMI is equivalent between two groups. The bone mineral density in males is higher than that in females, the bone mineral density is highest on neck of femur and lowest on trochiter. The rate of osteomalacia on the upper part of femur was 31.5%. The density of the neck of femur in male group is higher than female ones. Weight, BMI and sport playing are factors related to crease bone density. Age, smoking and alcohol drinking are factors that lessen the bone density. For the elders, it is nesesay to measure the bone density in order to have preventive methods and appropriate treatment, avoid bone facture later.
Femur
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Aged
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Bone Density
7.The treatment of active chronic B hepatitis using lamivudine
Journal of Medical and Pharmaceutical Information 2004;0(7):28-31
This randomized, placebo-controlled clinical study evaluated the efficacy of lamivudine in 44 Vietnamese patients with histologically documented chronic hepatitis B for one-year. The patients were randomly assigned to receive 100 mg of lamivudine (22 patients) orally once daily or placebo (22 patients). The patients underwent liver biopsies before entering the study and after completing the assigned treatment regimen. At the end of therapy, the percentage of serum HBVDNA negativation was higher in the lamivudine group (86.4%) than in the control group (22% P<0.05). The rate of HBe/antiHBe seroconversion was statistically different between 2 groups (35.2% in the lamivudine group compared to 12.5% in the controls). 95.5% of the patients received lamivudine had normal alanine aminotransferase levels (versus 18.2% in the placebo). Median change in HAI score was >2 points of improvement versus placebo. Lamivudine is less side effects, safety, and favorable
Hepatitis B, Chronic
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Lamivudine
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Hepatitis B
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Therapeutics
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drugs
8.Effectiveness of community based campaign for larvae reduction in Ben Tre province
Journal of Practical Medicine 2005;512(5):57-61
A community based campaign for larvae reduction was organized in 3 communes Hoa Loc, An Thoi, Tan Trung of Mo Cay district, Ben Tre province in 2002. The results: the model of campaign expressed clearly the effectiveness and feasibility in larvae and mosquitos density’ reduction immediately after implementing. Furthermore, launching three to four campaigns times per year can maintain its effectiveness in long time. To gain the most effectiveness, all methods were urged implementing for changes in people’s behaviours and close combination between government, health training communication and regulations
Larva
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Epidemiology
9.Observation on the result of treament of thyroid nucleus tumor by infection of ethanol in to the tumor through skin
Journal of Practical Medicine 2003;469(12):46-47
From 1998 to 2002, 117 patients (99 females, 18 males, aged 17-69) with thyroid nucleus tumors at Hospital 7 in Hai Duong and Hospital Buu Dien I in Hanoi was given percutaneous injected ethanol. Among 82/117 patients (70.1%) good results and 29/117 (24.8%) moderate results achieved. With mononucleus tumor 67 patients had got good results, 15 with moderate results and 2 without results. With polynucleus tumor, 15 patients had got good results, 14 moderate results and 4 without result. The treatment was safe complications were not severe and easy to manage
Ethanol
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Thyroid Gland
;
Neoplasms
10.Herpes simplex virus encephalitis: case report
Ho Chi Minh city Medical Association 2003;8(3):169-170
A case of herpes simplex viral encephalitis was clinically determined and EEC imaging examination was carried out. The condition was well responsive with acyclovir. Acychovir was well tolerated, effective and safe.
Encephalitis Viruses
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Herpes Simplex
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Encephalitis, Herpes Simplex