The study involved 30 patients (21 males, 9 females, aged from 18 to 77) who had gastroduodenal ulcer-caused bleeding at the Hospital 103 between October 1999 to July 2000. Common symptoms included dizziness, tar-like stool, fatigue and fast pulse. The patients received Sandostanin 0.1 mg two ampoule mixed in 500 ml isotonic glucose or saline solution intravenous for 4 - 5 hours in consecutive 3 days. Results: Sandostanin (octreotid) is effective for gastroduodenal ulcer-caused bleeding, stops bleeding rapidly even in first day (93.4%), reduce the amount of transfused blood, shorten the stay duration, reduce the relapse, rate of induced sclerotization and operation is lowered. Sandostanin is safe, almost free of adverse effects and should be indicated early.
Peptic Ulcer ; Hemorrhage ; Peptic Ulcer Hemorrhage ; Pharmaceutical Preparations ; therapeutics

Antibiotic resistance is the most important factor leading to the failure of eradication regimens. This review focuses on the prevalence of Helicobacter pylori primary and secondary resistance to clarithromycin, metronidazole, amoxicillin, levofloxacin, tetracycline, and multidrug in Vietnam. We searched the PubMed, EMBASE, Vietnamese National Knowledge Infrastructure, and Vietnamese Biomedical databases from January 2000 to December 2016. The search terms included the following: H. pylori infection, antibiotic (including clarithromycin, metronidazole, amoxicillin, levofloxacin, tetracycline, and multidrug) resistance in Vietnam. The data were summarized in an extraction table and analyzed manually. Finally, Excel 2007 software was used to create charts. Ten studies (three studies in English and seven in Vietnamese) were included in this review. A total of 308, 412, 523, 408, 399, and 268 H. pylori strains were included in this review to evaluate the prevalence of H. pylori primary resistance to amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance, respectively. Overall, the primary resistance rates of amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance were 15.0%, 34.1%, 69.4%, 27.9%, 17.9% and 48.8%, respectively. Secondary resistance rates of amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance were 9.5%, 74.9%, 61.5%, 45.7%, 23.5% and 62.3%, respectively. In Vietnam, primary and secondary resistance to H. pylori is increasing over time and affects the effectiveness of H. pylori eradication.
Amoxicillin ; Asian Continental Ancestry Group ; Bismuth ; Clarithromycin ; Drug Resistance, Microbial ; Drug Resistance, Multiple ; Helicobacter pylori ; Helicobacter ; Humans ; Levofloxacin ; Metronidazole ; Prevalence ; Tetracycline ; Vietnam