The DEVIEMED programme (Joint programme of Vietnam and Germay) realization showed the state of caries among 210 children aged 6-12 years old with congenital defect of palatine clef and hare-lip treated at Hue Central Hospital in 1999-2004 year period. The prevalence of caries in children with palatine clef and hare lip was 70.5%, prevalence of los teeth 18.4%, of stoped teeth 6.2%. The detection, management dental congenital defect and the dental care services needed to improve at all levels.
Dental Caries ; Cleft Lip ; Cleft Palate ; Child ; Therapeutics

48 cases of facial skin cancer (18 males, 30 females, aged 8-83 years) were admitted in Hue Central Hospital in 1996 – 2003 period. Among them, basocell cancers were common and leading causes on the face and neck areas. The disease occurred mainly in > 50 years old age, more common in female than in male, in rural people than in urban and most occurred in the centre of the face. Sun irradiation was the mainly important risk factor. Clinically, basocell cancer on the face was detected late with slow progress, little gland and no far metastasis. Basocell cancers had got good prognosis. Large removal the surrounding tissues and using local flap flexibly according the concrete site gave good outcomes functionally and esthetically.
Skin Neoplasms ; Case reports ; Maxillofacial Abnormalities ; Therapeutics

Objective To evaluate the antitumor activity both in vitro and in vivo of saponin–phospholipid complex of Panax notoginseng. Methods The in vitro cytotoxic effect of saponins extract and saponin–phospholipid complex against human lung cancer NCI-H460 and breast cancer cell lines BT474 was examined using MTS assay. For in vivo evaluation of antitumor potential, saponin and saponin–phospholipid complex were administered orally in rats induced mammary carcinogenesis by 7,12-dimethylbenz(a)anthracene, for 30 days. Results Our data showed that saponin–phospholipid complex had stronger anticancer effect compared to saponin extract. The IC50 values of saponin–phospholipid complex and saponin extract for NCI-H460 cell lines were 28.47 μg/mL and 47.97 μg/mL, respectively and these values for BT474 cells were 53.18 μg/mL and 86.24 μg/mL, respectively. In vivo experiments, administration of saponin, saponin–phospholipid complex and paclitaxel (positive control) effectively suppressed 7,12-dimethylbenz(a) anthracene-induced breast cancer evidenced by a decrease in tumor volume, the reduction of lipid peroxidation level and increase in the body weight, and elevated the enzymatic antioxidant activities of superoxide dismutase, catalase, glutathione peroxidase in rat breast tissue. Conclusions Our study suggests that saponin extract from Panax notoginseng and saponin–phospholipid complex have potential to prevent cancer, especially breast cancer.