1.Standardization of the product of ketoprofen gel
Pharmaceutical Journal 2004;44(1):21-24
In this study, gel ketoprofen, which has been used as an non-steroidal anti-inflammatory agent, was standardized on appearance, weight uniformity, pH, particulate matter, viscosity, identification, and assay. By using UV spectrophotometry, ketoprofen was quantified using methanol as its solvent. This method was accurate, sensitive, precise, and reproducible
Anti-Inflammatory Agents
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Ketoprofen
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Pharmaceutical Preparations
2.Standardization of erythromycine gel product
Pharmaceutical Journal 2004;44(6):23-26
Gel erythromycin 4% (type 10g) was compounded in 3 lot at Pharmacy Department of the School of Medicine and Pharmacy Can Tho. The method: Carring out test on 3 lot of product aim to build the criteria, each lot was tested minimum 3 times for criteria including apperance, vicosity, pH, particulate matter, weight uniformity, identification and assay. The result: The draft of test criteria for gel erythromycin was buitt to contribute introduce this subject into phamacopoeia. Additionaly, quantitative determination of erythromycin in the gel product was carried out by microbiological method
Erythromycin
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Pharmaceutical Preparations
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Gels
3.Study on technique of manufacture of ketoprofen gel
Pharmaceutical Journal 2003;9(6):12-14
Ketoprofen gel is a medical product used to treat musculoosteoarthropathy. Establishing process to make up gel product achieve pharmaceutical quality criteria by formula to create gel product, optimized formula by defined experimentation, investigated about abilities released ketoprifen through membrane compared profenid gel, investigated upset ability of product, then estimated pharmaceutical effect of gel. Initially we investigated stabilization of the products in natural environment, and predicted life-span of the drug is 27 months similar a imported product
Ketoprofen
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Manufactured Materials
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Cosmetic Techniques
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drugs
4.Evaluate on epidemic supervision and propose solutions to protect healthy for soldiers and people in malaria epidemic area.
Ngo Van Ly ; Thuan Khanh Le ; Loc Ba Ly ; Doan Van Nguyen ; Sinh Cong Nguyen ; Tuan Dinh Trinh ; Duc Ai Quach ; Thao Duc Nguyen ; Thuc Duy Nguyen ; Binh Van Nguyen ; Thang Duc Do
Journal of Malaria and parasite diseases Control 2003;0(1):13-24
Background: Coordinating between soldiers and people bring significant results in protecting healthy for soldiers and people in malaria epidemic area.\r\n', u'Objectives: To evaluate epidemic supervision and propose solutions protecting healthy for soldiers and people in malaria epidemic area.\r\n', u'Subjects and methods: A retrospective cross sectional study was carried out on two provinces Binh Phuoc and Dak Lak\r\n', u'Results: there was 4 main disease types were fever, tuberculosis, diarrhea and malaria. Malaria at investigated times still accounted high rate comparing with general fever rate. Malaria risk contained in people living or working in forest and mountain field; free emigrants; armed forces and border guard. These subjects needed to improve regularly protection from malaria. Communication of health education is one of important method to prevent and control malaria.\r\n', u'Conclusion: It is necessary to implement strong methods (such as providing insecticide treated bed nets, indoor residual spray) to prevent and control malaria. \r\n', u'
Epidemic supervision
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healthy
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soldier
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malaria epidemic area.
5.Ethanol extracts of Scutellaria baicalensis protect against lipopolysaccharide-induced acute liver injury in mice
Thanh Nguyen Hai ; Le Anh Tuan ; Huu Nguyen Tung ; Duc Vu Loi ; Kim Dang Thu ; Thanh Bui Tung
Asian Pacific Journal of Tropical Biomedicine 2015;(9):733-738
To investigated the protective potential of ethanol extracts of Scutellaria baicalensis (S. baicalensis ) against lipopolysaccharide (LPS)-induced liver injury. Methods: Dried roots of S. baicalensis were extracted with ethanol and concentrated to yield a dry residue. Mice were administered 200 mg/kg of the ethanol extracts orally once daily for one week. Animals were subsequently administered a single dose of LPS (5 mg/kg of body weight, intraperitoneal injection). Both protein and mRNA levels of cytokines, such as tumor necrosis factor alpha, interleukin-1β, and interleukin-6 in liver tissues were evaluated by ELISA assay and quantitative PCR. Cyclooxygenase-2, inducible nitric oxide synthase, and nuclear factor-κB protein levels in liver tissues were analyzed by western blotting. Results: Liver injury induced by LPS significantly increased necrosis factor alpha, interleukin-1β, interleukin-6, cyclooxygenase-2, inducible nitric oxide synthase, and nuclear factor-κB in liver tissues. Treatment with ethanol extracts of S. baicalensis prevented all of these observed changes associated with LPS-induced injury in liver mice. Conclusions: Our study showed that S. baicalensis is potentially protective against LPS-induced liver injury in mice.
6.Lean mass and peak bone mineral density
Huy G. NGUYEN ; Minh TD. PHAM ; Lan T. HO-PHAM ; Tuan V. NGUYEN
Osteoporosis and Sarcopenia 2020;6(4):212-216
Objectives:
The association between body composition parameters and peak bone mineral density is not well documented. The aim of this study is to assess the relative contributions of lean mass and fat mass on peak bone mineral density (BMD).
Methods:
The study involved 416 women and 334 men aged between 20 and 30 years who were participants in the population-based Vietnam Osteoporosis Study. Whole body composition parameters (eg, fat mass and lean mass) and BMD at the lumbar spine and femoral neck were measured by dual-energy X-ray absorptiometry. The association between lean mass and fat mass and BMD was analyzed by the linear regression model using the Least Absolute Shrinkage and Selection Operator (LASSO).
Results:
Peak BMD in men was higher than women, and the difference was more pronounced at the femoral neck (average difference: 0.123 g/㎠; 95% confidence interval [CI] 0.105–0.141 g/㎠) than at the lumbar spine (average difference 0.019 g/㎠; 95% CI, 0.005–0.036 g/㎠). Results of LASSO regression indicated that lean mass was the only predictor of BMD for either men or women. Each kilogram increase in lean mass was associated with ∼0.01 g/㎠ increase in BMD. Lean mass alone explained 16% and 36% of variation in lumbar spine and femoral neck BMD, respectively.
Conclusions
Lean mass, not fat mass, is the main determinant of peak bone mineral density. This finding implies that good physical activity during adulthood can contribute to the maximization of peak bone mass during adulthood.
7.Lean mass and peak bone mineral density
Huy G. NGUYEN ; Minh TD. PHAM ; Lan T. HO-PHAM ; Tuan V. NGUYEN
Osteoporosis and Sarcopenia 2020;6(4):212-216
Objectives:
The association between body composition parameters and peak bone mineral density is not well documented. The aim of this study is to assess the relative contributions of lean mass and fat mass on peak bone mineral density (BMD).
Methods:
The study involved 416 women and 334 men aged between 20 and 30 years who were participants in the population-based Vietnam Osteoporosis Study. Whole body composition parameters (eg, fat mass and lean mass) and BMD at the lumbar spine and femoral neck were measured by dual-energy X-ray absorptiometry. The association between lean mass and fat mass and BMD was analyzed by the linear regression model using the Least Absolute Shrinkage and Selection Operator (LASSO).
Results:
Peak BMD in men was higher than women, and the difference was more pronounced at the femoral neck (average difference: 0.123 g/㎠; 95% confidence interval [CI] 0.105–0.141 g/㎠) than at the lumbar spine (average difference 0.019 g/㎠; 95% CI, 0.005–0.036 g/㎠). Results of LASSO regression indicated that lean mass was the only predictor of BMD for either men or women. Each kilogram increase in lean mass was associated with ∼0.01 g/㎠ increase in BMD. Lean mass alone explained 16% and 36% of variation in lumbar spine and femoral neck BMD, respectively.
Conclusions
Lean mass, not fat mass, is the main determinant of peak bone mineral density. This finding implies that good physical activity during adulthood can contribute to the maximization of peak bone mass during adulthood.
8.Cost of Hospitalization for Foodborne Diarrhea: A Case Study from Vietnam.
Van Minh HOANG ; Tuan Anh TRAN ; Anh Duc HA ; Viet Hung NGUYEN
Journal of Korean Medical Science 2015;30(Suppl 2):S178-S182
Vietnam is undergoing a rapid social and economic developments resulting in speedy urbanization, changes in methods for animal production, food marketing systems, and food consumption habits. These changes will have major impacts on human exposures to food poisoning. The present case study aimed to estimate hospitalization costs of foodborne diarrhea cases in selected health facilities in Vietnam. This is a facility-based cost-of-illness study conducted in seven health facilities in Northern Vietnam. All suspect cases of foodborne diarrhea, as diagnosed by doctors, who admitted to the studied health facilities during June-August, 2013 were selected. Costs associated with hospitalization for foodborne diseases were estimated from societal perspective using retrospective approach. We included direct and indirect costs of hospitalization of foodborne diarrhea cases. During the study period, 87 foodborne diarrhea cases were included. On average, the costs per treatment episode and per hospitalization day for foodborne diarrhea case were US$ 106.9 and US$ 33.6 respectively. Indirect cost (costs of times to patient, their relatives due to the patient's illness) made up the largest share (51.3%). Direct medical costs accounted for 33.8%; direct non-medical costs (patient and their relatives) represented 14.9%. Cost levels and compositions varied by level of health facilities. More attentions should be paid on prevention, control of foodborne diarrhea cases in Vietnam. Ensuring safety of food depends on efforts of everyone involved in food chain continuum, from production, processing, and transport to consumption.
Adolescent
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Adult
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Age Distribution
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Aged
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Child
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Child, Preschool
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*Cost of Illness
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Diarrhea/*economics/epidemiology
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Female
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Foodborne Diseases/*economics/epidemiology
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Health Care Costs/*statistics & numerical data
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Hospitalization/*economics
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Humans
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Infant
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Infant, Newborn
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Male
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Middle Aged
;
Prevalence
;
Risk Factors
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Sex Distribution
;
Vietnam/epidemiology
;
Young Adult
9.The Vietnam Osteoporosis Study: Rationale and design.
Osteoporosis and Sarcopenia 2017;3(2):90-97
OBJECTIVES: Osteoporosis and fracture impose a significant health care burden on the contemporary populations in developing countries. The Vietnam Osteoporosis Study (VOS) sought to assess the burden of osteoporosis and its comorbidities in men and women. METHODS: The study was designed as a population-based family investigation in which families were randomly recruited from Ho Chi Minh City, Vietnam. Individuals were assessed for bone health, including bone mineral density (BMD) and body composition and trabecular and cortical bone properties by pQCT (peripheral quantitative computed tomography). Fasting blood samples were obtained for the analysis of plasma glucose, glycosylated hemoglobin, and bone turnover markers. Genomic DNA extraction from whole blood samples for further genetic and genomic analyses. RESULTS: We have recruited more than 4157 individuals from 817 families. The average age of participants was 51, with approximately 45% of the individuals aged 50 years and older. Approximately 3% of participants were obese (body mass index ≥ 30 kg/m²), and 21% were overweight. Notably, 11% of participants aged 40 years and older were diabetic. Among those aged 50 years and older, approximately 14% of women and 5% of men had osteoporosis (i.e., femoral neck BMD T-scores ≤−2.5). There were modest correlations between volumetric BMD and areal BMD. CONCLUSIONS: VOS is a major bone research project in Vietnam aimed at comprehensively documenting the burden osteoporosis, its co-occurrence of chronic diseases, and their underlying etiologies. The Study will make important contributions to the literature of bone health worldwide.
Blood Glucose
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Body Composition
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Bone Density
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Bone Remodeling
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Chronic Disease
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Comorbidity
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Delivery of Health Care
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Developing Countries
;
DNA
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Fasting
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Female
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Femur Neck
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Hemoglobin A, Glycosylated
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Humans
;
Male
;
Muscle Strength
;
Osteoporosis*
;
Overweight
;
Sarcopenia
;
Vietnam*
10.Identification of Enterovirus C105 for the first time in New Zealand
Cong Thanh Duong ; Tran Hien Nguyen ; Anh Tuan Nguyen ; Thi Thanh Ha Hoang ; Hong Thang Pham ; Thi THanh Ha Nguyen ; Anh Tuan Le ; Dai Quang Tran ; Hong Tram Tran ; Le Hai Nguyen ; Thi Thu Huong Phan ; Hai Son Vo ; Hoang Duc Bui ; Thien Nga Nguyen ; David Jacka ; Keith Sabin
Western Pacific Surveillance and Response 2015;6(1):52-54
In this report we describe a new approach in HIV sentinel surveillance that was piloted in Viet Nam in 2009 and is currently being rolled out in all provinces. It comprises a brief behavioural questionnaire added to the HIV sentinel surveillance surveys conducted routinely among people who inject drugs, female sex workers and men who have sex with men. Timely reporting of data from this system has resulted in improvements to HIV prevention efforts for most at-risk populations.