The expression of HB-EGF (heparine binding epidermal growth factor) in cells of mice increased just after partial level removal in hapatectomy and reached maximal value 3 hours later. TGF-A expression in mice cells after 2/3 hepatectomy reduced in comparing with control in 3 first hours later and increased in 6 hours later
Liver ; Hepatectomy ; Mice

Guinea-pig liver cells primitive culture completed with 1.5-50 ng/ml of hFGF-10 promote the biosynthesis of ADN in these cells. The concentration of 25 ng/ml produces the highest effect in primitive culture of guinea-pig liver cells, the stimuli effect to mytosis of hFGF-10 is equal with hFGF-1 and hFGF-7. Heparin did not manifest any influence to the effect of hFGF-10 on guinea-pig primitive cultured cells
Fibroblast Growth Factor 10 ; Liver ; Guinea ; cells ; Culture ; DNA

Adult made IRC white mouse of 21 week age, weighing 22-25 g underwent an operation for removing the liver, which was washed with PBS buffer. Total ARN extracted from clean mouse liver composes of 3 characteristic band 28S, 18S and 5S. Total ARN concentration received was 10Ug/Ul approximatively. Received PCR product is a characteristic band of the size of some 630bp corresponded to the size of mFGF-21. It is a total gene of mFGF-21 with a sequence 100% corresponding to the registered sequence in the gene international data Bank Number NM-020013
Fibroblast Growth Factors ; Mice ; Liver

Trichobakin (TBK) is a type I ribosom inactivating protein (RIP) from the plant Trichosanthes sp. BacKan 8-98 (Cucurbitaceae). This study introduces some results of experimental trial of TBK effects in vivo on the ascitic Sarcoma-180 (S-180) cancer cells in Swiss mice. Results: Injection TBK with dose of 40 µg/mice is effective in (1) inhibiting the growth of S-180 cells with rate of 99.9% after 15 days of S-180 cell transplantation, (2) increasing survival of treated mice up to 175% versus controlled mice in the 90 experimental day period
Growth ; Sarcoma ; Neoplasms

Objective: In Viet Nam, tuberculosis (TB) prevalence surveys revealed that approximately 98% of individuals with pulmonary TB have TB-presumptive abnormalities on chest radiographs, while 32% have no TB symptoms. This prompted the adoption of the “Double X” strategy, which combines chest radiographs and computer-aided detection with GeneXpert testing to screen for and diagnose TB among vulnerable populations. The aim of this study was to describe demographic, clinical and radiographic characteristics of symptomatic and asymptomatic Double X participants and to assess multilabel radiographic abnormalities on chest radiographs, interpreted by computer-aided detection software, as a possible tool for detecting TB-presumptive abnormalities, particularly for subclinical TB. Methods: Double X participants with TB-presumptive chest radiographs and/or TB symptoms and known risks were referred for confirmatory GeneXpert testing. The demographic and clinical characteristics of all Double X participants and the subset with confirmed TB were summarized. Univariate and multivariable logistic regression modelling was used to evaluate associations between participant characteristics and subclinical TB and between computer-aided detection multilabel radiographic abnormalities and TB. Results: From 2020 to 2022, 96 631 participants received chest radiographs, with 67 881 (70.2%) reporting no TB symptoms. Among 1144 individuals with Xpert-confirmed TB, 51.0% were subclinical. Subclinical TB prevalence was higher in older age groups, non-smokers, those previously treated for TB and the northern region. Among 11 computer-aided detection multilabel radiographic abnormalities, fibrosis was associated with higher odds of subclinical TB. Discussion: In Viet Nam, Double X community case finding detected pulmonary TB, including subclinical TB. Computer-aided detection software may have the potential to identify subclinical TB on chest radiographs by classifying multilabel radiographic abnormalities, but further research is needed.